Citations 2
Observer Performance for Detection of Pulmonary Nodules at Chest CT over a Large Range of Radiation Dose Levels
Fletcher, Joel G. , Levin, David L. , Sykes, Anne-Marie , Lindell, Rebecca M. , White, Darin , Suresh, Vighnesh , Yu, Lifeng , Leng, Shuai , Holmes, David R. , Inoue, Akitoshi , Johnson, Matthew P. , Carter, Rickey E. , Sykes, Anne-Marie G , White, Darin B , Kuzo, Ronald S , Suresh, Vighnesh , Yu, Lifeng , Leng, Shuai , Johnson, Matthew P , Carter, Rickey E , McCollough, Cynthia H , Fletcher, Joel G , Inoue, Akitoshi , Kuzo, Ronald S. , McCollough, Cynthia H.
Radiology | September 29, 2020 | Volume: 297 | Issue: 3 | Pages: 699-707
Individualized Delay for Abdominal Computed Tomography Angiography Bolus-Tracking Based on Sequential Monitoring: Increased Aortic Contrast Permits Decreased Injection Rate and Lower Iodine Dose
Gutjahr, Ralf , Lee, Yong S. , Halaweish, Ahmed F., Suresh, Vighnesh , Weber, Nikkole M. , Vrtiska, Terri J., Williamson, Eric E. , Schmidt, Bernhard , Fletcher, Joel G. , McCollough, Cynthia H.
Journal of Computer Assisted Tomography | July 3, 2019 | Volume: 43 | Issue: 4 | Pages: 612-618
Objective The aim of this study was to determine if computed tomography (CT) angiography using an individualized transition delay (CTA-ID) would facilitate reductions in injection rate and iodine dose. Methods The CTA-ID was performed in 20 patients with routine injection rate and iodine dose; 20 patients with injection rate lowered by 1 mL/s; and 40 patients with injection rate lowered by 1 mL/s with 29% less iodine. Routine CTAs in the same or size-matched patients served as controls. Diagnostic image quality and intra-arterial CT numbers were assessed. Results The median transition delay between aortic threshold and CTA-ID image acquisition was significantly longer than with conventional bolus tracking (mean increase, 13.3 seconds; P < 0.0001), with image quality being the same or better. Intra-arterial CT numbers were 200 Hounsfield units or greater for 80 of 80 CTA-ID, but not for 6 of 49 (12%) internal control or for 11 of 80 (14%) size-matched control patients. Conclusion The CTA-ID bolus-tracking software alters transition delays to permit diagnostic CTA examinations despite slower injection rate and less iodine.