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Shin, Alexander Y.

https://orcid.org/0000-0001-9658-8192

Mayo Clinic

Mayo Clinic

Citations 194

Adult Brachial Plexus Injuries: Treatment in the Acute Phase
Rodriguez, Maria Cristina, Shin, Alexander Y.

Cirugía de Mano y Microcirugía | July 4, 2024 | Volume: 3 | Issue: 1 | Pages: No page available

10.25214/28056272.1678 Get It

Brachial Plexus Injuries are a catastrophic situation that affects patients on many levels. While many treatment options are discussed in the literature, general treatment principles should be applied, especially in the acute phase. In addition to the surgeon's expert knowledge of anatomy and injury characteristics, education of the patient concerning the ramifications of their injury and providing clear expectations of realistic outcomes are imperative for both the surgeon and the patient. A review of the principles of acute surgical treatment will be presented.
Evaluation of the cutaneous blood supply and vascular territories of the wrist
Alder, Kareme D. , Kattil, Punnose , Lachman, Nirusha , Shin, Alexander Y. , Shin, Alexander Y , Kattil, Punnose K , Meaike, Joshua J. , Pulos, Nicholas

Orthoplastic Surgery | May 30, 2024 | Volume: 16 | Issue: C | Pages: 20-30

10.1016/j.orthop.2024.05.002 Get It

ABSTRACT Purpose: To determine and evaluate the distal forearm and wrist's cutaneous blood supply and vascular territories. Methods: Four cadaveric upper extremities were injected with a radiopaque, lead-based contrast agent through the brachial artery. After the lead-based contrast agent set, the cadaveric limbs underwent computed tomographic (CT) scanning to assess the perforators to the cutaneous skin of the distal forearm and wrist. High-resolution axial CT and three-dimensional reconstructions were generated to highlight perforating vessels stemming from their parent arteries. Subsequently, anatomic microdissections were performed to identify and trace the perforating vessels identified on CT. Results: CT analysis and anatomic microdissection demonstrated that the dorsal surface of the distal forearm and wrist are supplied by numerous perforators stemming predominantly from the anterior interosseous artery with some anastomotic contribution from the posterior interosseous, radial, and ulnar arteries. Perforators from the radial and ulnar arteries supply the volar surface. There are large anastomotic networks formed between the perforating vessels. Conclusions: The distal forearm and wrist have a robust anastomotic blood supply that has contributions from the anterior interosseous, posterior interosseous, radial, and ulnar arteries. Clinical relevance: The extensive perforator-derived blood supply to the skin likely accounts for the excellent soft tissue healing potential of the wrist following surgery utilizing multiple incisions. Highlights Distal radius fractures may require multiple incisions for anatomic reduction and fixation.Multiple incisions about the wrist are thought to predispose to wound complications and/or skin breakdown.The distal forearm and wrist have a robust anastomotic blood supply from the anterior interosseous, posterior interosseous, radial, and ulnar arteries.Multiple incisions do not necessarily predispose to wound complications given robust anastamosis.
Evaluating the Ability of Brachial Plexus-Injured Patients to Control an Externally Powered (Myoelectric) Hand Prosthesis
Lee, Ellen Y. , NELSON, A. WENDELL , Sampson, Brandon P. , Smither, F. Clay , Pulos, Nicholas , Bishop, Allen T. , Spinner, Robert J. , Shin, Alexander Y. , Shin, Alexander Y , Bishop, Allen T , Pulos, Nicholas

Journal of Bone and Joint Surgery | May 10, 2024 | Volume: 106 | Issue: 24 | Pages: 2375-2382

10.2106/jbjs.23.00938 Get It

Background: Restoration of hand function after traumatic brachial plexus injury (BPI) remains a formidable challenge. Traditional methods such as nerve or free muscle transfers yield suboptimal results. Advancements in myoelectric prostheses, characterized by novel signal acquisition and improved material technology, show promise in restoring functional grasp. This study evaluated the ability of adults with a BPI injury to control an externally powered prosthetic hand using nonintuitive signals, simulating the restoration of grasp with a myoelectric prosthesis. It also assessed the effectiveness of a comprehensive multidisciplinary evaluation in guiding treatment decisions. Methods: A multidisciplinary brachial plexus team assessed adults with compromised hand function due to BPI. The feasibility of amputation coupled with fitting of a myoelectric prosthesis for grasp reconstruction was evaluated. Participants' ability to control a virtual or model prosthetic hand using surface electromyography (EMG) as well as with contralateral shoulder motion-activated linear transducer signals was tested. The patient’s input and injury type, along with the information from the prosthetic evaluation, were used to determine the reconstructive plan. The study also reviewed the number of participants opting for amputation and a myoelectric prosthetic hand for grasp restoration, and a follow-up survey was conducted to assess the impact of the initial evaluation on decision-making. Results: Of 58 subjects evaluated, 47 (81%) had pan-plexus BPI and 42 (72%) received their initial assessment within 1 year post-injury. Forty-seven patients (81%) could control the virtual or model prosthetic hand using nonintuitive surface EMG signals, and all 58 could control it with contralateral uniscapular motion via a linear transducer and harness. Thirty patients (52%) chose and pursued amputation, and 20 (34%) actively used a myoelectric prosthesis for grasp. The initial evaluation was informative and beneficial for the majority of the patients, especially in demonstrating the functionality of the myoelectric prosthesis. Conclusions: The study indicates that adults with traumatic BPI can effectively operate a virtual or model myoelectric prosthesis using nonintuitive control signals. The simulation and multidisciplinary evaluation influenced informed treatment choices, with a high percentage of patients continuing to use the myoelectric prostheses post-amputation, highlighting its long-term acceptance and viability. Level of Evidence: Therapeutic Level IV . See Instructions for Authors for a complete description of levels of evidence.
The role of vascularized bone grafting for scaphoid nonunions in adolescents
Israel, Jacqueline S. , Pulos, Nicholas , Pulos, Nicholas , Bishop, Allen T. , Shin, Alexander Y.

Journal of Hand Surgery (European Volume) | April 25, 2024 | Volume: 49 | Issue: 9 | Pages: 1157-1159

10.1177/17531934241247279 Get It

A total of 26 adolescent patients were treated for scaphoid nonunion with a vascularized bone graft from either the medial femoral condyle or dorsal distal radius. There was an 85% union incidence, improved carpal alignment and a low incidence of complications.
SP49. Outcomes Of Myoelectric Prosthetic Fitting On Activity Performance In Patients With Traumatic Brachial Plexus Injuries (BPI) After Elective Amputation
Saffari, Tiam M. , Nelson, Andrew W. , Samson, Brandon, Smithers, Clayton, Nelson, Andrew, Pulos, Nicholas , Shin, Alexander Y.

Plastic and Reconstructive Surgery - Global Open | April 19, 2024 | Volume: 12 | Issue: S4 | Pages: 111-112

10.1097/01.gox.0001015760.24131.9f Get It

Design and Development of a Powered Myoelectric Elbow Orthosis for Neuromuscular Injuries
Vignola, Claudio, Bhat, Sandesh G. , Hollander, Kevin W., Kane, Paul H., Miller, Emily J. , Martin, W. Brandon , Shin, Alexander Y. , Sugar, Thomas G. , Kane, Paul, Miller, Emily , Kaufman, Kenton R , Shin, Alexander Y , Bhat, Sandesh G , Kaufman, Kenton R.

Military Medicine | April 3, 2024 | Volume: 189 | Issue: Supplement_3 | Pages: 585-591

10.1093/milmed/usae196 Get It

ABSTRACT Introduction Recovering from neuromuscular injuries or conditions can be a challenging journey that involves complex surgeries and extensive physical rehabilitation. During this process, individuals often rely on orthotic devices to support and enable movement of the affected limb. However, users have criticized current commercially available powered orthotic devices for their bulky and heavy design. To address these limitations, we developed a novel powered myoelectric elbow orthosis. Materials and Methods The orthosis incorporates 3 mechanisms: a solenoid brake, a Bowden cable-powered constant torque elbow mechanism, and an extension limiter. The device controller and battery are in a backpack to reduce the weight on the affected arm. We performed extensive calculations and testing to ensure that the orthosis could withstand at least 15 Nm of elbow torque. We developed a custom software effectively control the orthosis, enhancing its usability and functionality. A certified orthotist fitted a subject who had undergone a gracilis free functioning muscle transfer surgery with the device. We studied the subject under Mayo clinic IRB no. 20-006849 and obtained objective measurements to assess the orthosis’s impact on upper extremity functionality during daily activities. Results The results are promising since the orthosis significantly improved elbow flexion range of motion by 40° and reduced compensatory movements at the shoulder (humerothoracic joint) by 50°. Additionally, the subject was able to perform tasks which were not possible before, such as carrying a basket with weights, highlighting the enhanced functionality provided by the orthosis. Conclusion In brief, by addressing the limitations of existing devices, this novel powered myoelectric elbow orthosis offers individuals with neuromuscular injuries/conditions improved quality of life. Further research will expand the patient population and control mechanisms.
Injury and Biological Factors Impact Shoulder Function following Autogenous Grafting of Spinal Nerves for Pan–Brachial Plexus Reconstruction
Wu, Kitty Y. , Loosbrock, Michelle F., Spinner, Robert J. , Li, Neill Y. , Bishop, Allen T. , Shin, Alexander Y.

Plastic & Reconstructive Surgery | April 2, 2024 | Volume: 154 | Issue: 5 | Pages: 918e-927e

10.1097/prs.0000000000011270 Get It

Background: Shoulder function after spinal nerve grafting in pan–brachial plexus injuries (pan-BPI) is not well described. The authors evaluated shoulder abduction (ABD) and external rotation (ER) after spinal nerve grafting to the suprascapular nerve, axillary nerve, or posterior division of the upper trunk and determined patient characteristics, injury severity and characteristics, and nerve graft factors that influenced outcomes. Methods: A total of 362 patients undergoing pan-BPI reconstruction and spinal nerve grafting for shoulder reanimation in a single institution between 2001 and 2018 were reviewed. Patient demographics, Injury Severity Score (ISS), graft characteristics, strength, range of motion for shoulder ABD and ER, and patient-reported outcomes were recorded. Patients were divided into 3 groups based on recovery of shoulder function: no return, ABD only, and ABD and ER. Results: A total of 110 patients underwent spinal nerve grafting, with 41 meeting inclusion criteria. Seventeen (41.5%) had no return of shoulder function, 14 (34.1%) had ABD alone, and 10 (24.4%) had ABD and ER. Patients with recovery of both ABD and ER were significantly younger (18.6 ± 5.56 years), had lower body mass index (22.4 ± 4.0), and had a lower ISS (10.5 ± 6.24; P = 0.003). Multivariable analysis found that with increasing age (OR, 0.786; 95% CI, 0.576, 0.941) and ISS (OR, 0.820; 95% CI, 0.606, 0.979), odds for return of ABD and ER decreased significantly. Conclusions: In pan-BPI, 24.4% of patients demonstrated return of both ABD and ER after spinal nerve grafting to suprascapular nerve and either axillary nerve or posterior division of the upper trunk. Age, body mass index, and ISS were associated with poorer recovery of shoulder function. Careful patient selection and consideration of age, body mass index, and ISS may improve outcomes of spinal nerve grafting for shoulder reanimation. CLINICAL QUESTION/LEVEL OF EVIDENCE: Risk, III.
The failed adult traumatic brachial plexus reconstruction
Lee, Ellen Y. , Spinner, Robert J. , Shin, Alexander Y. , Shin, Alexander Y , Pulos, Nicholas , Bishop, Allen T.

Journal of Hand Surgery (European Volume) | February 19, 2024 | Volume: 49 | Issue: 11 | Pages: 1298-1312

10.1177/17531934241231170 Get It

Traumatic adult brachial plexus injuries typically cause immediate loss of upper limb function. Timely multidisciplinary treatment in specialized centres often results in a useful helper arm. Both the patient and the surgical team can benefit from an open discussion to set realistic expectations. Surgical reconstruction is customized for each patient, considering their injury factors and functional objectives. Optimizing pain control, adherence to procedure indications and using meticulous surgical techniques help minimize the risk of failing to meet the patient’s goals. The need for potential alternative treatment(s) if the desired result is not achieved should be detailed before the initial reconstruction. This review discusses late treatment options, including tendon transfers, joint fusions, free functioning muscle transfers and prosthetics, for managing the failed primary reconstruction of the traumatic adult brachial plexus.
Global trends and outcomes of nerve transfers for treatment of adult brachial plexus injuries
Crowe, Christopher S. , Spinner, Robert J. , Shin, Alexander Y. , Shin, Alexander Y

Journal of Hand Surgery (European Volume) | February 19, 2024 | Volume: 49 | Issue: 9 | Pages: 1147-1156

10.1177/17531934241232062 Get It

The presentation, management and outcomes of brachial plexus injuries are likely to be subject to regional differences across the globe. A comprehensive literature search was performed to identify relevant articles related to spinal accessory to suprascapular, intercostal to musculocutaneous, and ulnar and/or median nerve fascicle to biceps and/or brachialis motor branch nerve transfers for treatment of brachial plexus injuries. A total of 6007 individual brachial plexus injuries were described with a mean follow-up of 38 months. The specific indication for accessory to suprascapular and intercostal to musculocutaneous transfers were considerably different among regions (e.g. upper plexus vs. pan-plexal), while uniform for fascicular transfer for elbow flexion (e.g. upper plexus +/− C7). Similarly, functional recovery was highly variable for accessory to suprascapular and intercostal to musculocutaneous transfers, while British Medical Research Council grade ≥3 strength after fascicular transfer for elbow flexion was frequently obtained. Overall, differences in outcomes seem to be inherent to the specific transfer being utilized. Level of evidence: III
Complications of operatively treated distal radial fractures
Townsley, Sarah, Shin, Alexander Y. , Townsley, Sarah H. , Shin, Alexander Y , Pulos, Nicholas

Journal of Hand Surgery (European Volume) | February 5, 2024 | Volume: 49 | Issue: 2 | Pages: 215-225

10.1177/17531934231192836 Get It

Distal radial fractures represent the most common fractures of the upper extremity. Operative treatment is performed for approximately one-third of distal radial fractures in the adult population. Complications following operative treatment of distal radial fractures vary depending on the treatment modality and can be stratified into preoperative and postoperative complications. Complications can occur in the near, intermediate and long term. The most common complications seen are tendon irritation and rupture, chronic regional pain syndrome (CRPS), carpal tunnel syndrome, ulnar or radial neuropathy, compartment syndrome, malunion, inadequate fixation or loss of fixation, symptomatic hardware, post-traumatic arthritis, stiffness and infection. Careful planning, treatment and patient selection can help to mitigate these complications. Level of evidence: V