Back to Authors

Pulos, Nicholas

0000-0001-8706-4522

Mayo Clinic

Mayo Clinic

Citations 12

Preliminary Results of Coracoid Excision for Anterior Shoulder Pain in Brachial Plexus Birth Injury
Lee, Ellen Y. , Shin, Alexander Y. , Shaughnessy, William J. , Pulos, Nicholas , Shin, Alexander Y , Pulos, Nicholas

Journal of Pediatric Orthopaedics | July 1, 2025 | Volume: 45 | Issue: 7 | Pages: e631-e636

10.1097/bpo.0000000000002952 Get It

Background: Secondary shoulder deformities are the most frequent sequelae of upper trunk-type brachial plexus birth injury (BPBI). Coracoid process dysplasia was recently described as being associated with glenoid retroversion and was recognized to block successful humeral head relocation. There are little to no reports on coracoid process deformity causing anterior shoulder pain. Our hypothesis is that coracoid process impingement causes anterior shoulder pain in BPBI, which is relieved by coracoid excision. This study presents the short-term results of this new technique in BPBI patients. Methods: A retrospective review identified BPBI patients who underwent coracoid excision from 2000 to 2022. Indications for this procedure include BPBI patients with anterior shoulder pain limiting the range of motion, localized tenderness over a prominent coracoid process, a dysplastic coracoid process seen on imaging, and persistent pain despite activity modification, medication, and therapy. Patient characteristics, preoperative shoulder pain score, range of motion, degree of glenohumeral subluxation, patient-reported outcomes measurement information system (PROMIS) scores for pain interference, and physical and upper extremity function were collected from chart review. Postoperative pain scores, range of motion, and PROMIS scores were collected at an average of 1 year after excision. Results: Five upper trunk BPBI patients, ages 10 to 25 years old, with anterior shoulder pain underwent coracoid excision. All had statistically significant pain relief from 6.5–8.5/10 before to 0–3/10 after the procedure. Forward flexion and external rotation improved by an average of 18 degrees. The pain interference score decreased by 25%. There was a 33% improvement in physical function scores and a 31% increase in upper extremity function scores. No complications or recurrence were observed at 7.5 months to 1 year and 7 months after surgery. Conclusions: Coracoid excision is a simple procedure that can relieve localized shoulder pain caused by coracoid impingement in adolescent/adult BPBI. Continued follow-up of all patients will be undertaken to determine long-term recurrence rates and complications. Level of Evidence: Level IV.
Preoperative Evaluation for Free Functional Muscle Transfer in Upper Extremity Amyoplasia
Sullivan, Mikaela H. , Vilkki, Simo K. , Venkatramani, Hari , Shin, Alexander Y. , Pulos, Nicholas , Shin, Alexander Y , Pulos, Nicholas , Sabapathy, Shanmuganathan Raja

JBJS Case Connector | August 1, 2024 | Volume: 14 | Issue: 3 | Pages: No page available

10.2106/jbjs.cc.24.00038 Get It

Case: A multicenter series of 3 patients with amyoplasia of the upper extremity were indicated for gracilis free functional muscle transfer (FFMT) to restore elbow flexion and found to have an absent gracilis. A final case is discussed detailing standardized evaluation with ultrasound to confirm gracilis before surgical intervention. Conclusion: In amyoplasia, the gracilis muscle may be absent or have fatty infiltration, making this donor muscle inadequate. Preoperative ultrasound to determine the presence of the gracilis is noninvasive and recommended in patients with amyoplasia of the upper extremity being considered for FFMT.
Evaluating the Ability of Brachial Plexus-Injured Patients to Control an Externally Powered (Myoelectric) Hand Prosthesis
Lee, Ellen Y. , NELSON, A. WENDELL , Sampson, Brandon P. , Smither, F. Clay , Pulos, Nicholas , Bishop, Allen T. , Spinner, Robert J. , Shin, Alexander Y. , Shin, Alexander Y , Bishop, Allen T , Pulos, Nicholas

Journal of Bone and Joint Surgery | May 10, 2024 | Volume: 106 | Issue: 24 | Pages: 2375-2382

10.2106/jbjs.23.00938 Get It

Background: Restoration of hand function after traumatic brachial plexus injury (BPI) remains a formidable challenge. Traditional methods such as nerve or free muscle transfers yield suboptimal results. Advancements in myoelectric prostheses, characterized by novel signal acquisition and improved material technology, show promise in restoring functional grasp. This study evaluated the ability of adults with a BPI injury to control an externally powered prosthetic hand using nonintuitive signals, simulating the restoration of grasp with a myoelectric prosthesis. It also assessed the effectiveness of a comprehensive multidisciplinary evaluation in guiding treatment decisions. Methods: A multidisciplinary brachial plexus team assessed adults with compromised hand function due to BPI. The feasibility of amputation coupled with fitting of a myoelectric prosthesis for grasp reconstruction was evaluated. Participants' ability to control a virtual or model prosthetic hand using surface electromyography (EMG) as well as with contralateral shoulder motion-activated linear transducer signals was tested. The patient’s input and injury type, along with the information from the prosthetic evaluation, were used to determine the reconstructive plan. The study also reviewed the number of participants opting for amputation and a myoelectric prosthetic hand for grasp restoration, and a follow-up survey was conducted to assess the impact of the initial evaluation on decision-making. Results: Of 58 subjects evaluated, 47 (81%) had pan-plexus BPI and 42 (72%) received their initial assessment within 1 year post-injury. Forty-seven patients (81%) could control the virtual or model prosthetic hand using nonintuitive surface EMG signals, and all 58 could control it with contralateral uniscapular motion via a linear transducer and harness. Thirty patients (52%) chose and pursued amputation, and 20 (34%) actively used a myoelectric prosthesis for grasp. The initial evaluation was informative and beneficial for the majority of the patients, especially in demonstrating the functionality of the myoelectric prosthesis. Conclusions: The study indicates that adults with traumatic BPI can effectively operate a virtual or model myoelectric prosthesis using nonintuitive control signals. The simulation and multidisciplinary evaluation influenced informed treatment choices, with a high percentage of patients continuing to use the myoelectric prostheses post-amputation, highlighting its long-term acceptance and viability. Level of Evidence: Therapeutic Level IV . See Instructions for Authors for a complete description of levels of evidence.
The role of vascularized bone grafting for scaphoid nonunions in adolescents
Israel, Jacqueline S. , Pulos, Nicholas , Pulos, Nicholas , Bishop, Allen T. , Shin, Alexander Y.

Journal of Hand Surgery (European Volume) | April 25, 2024 | Volume: 49 | Issue: 9 | Pages: 1157-1159

10.1177/17531934241247279 Get It

A total of 26 adolescent patients were treated for scaphoid nonunion with a vascularized bone graft from either the medial femoral condyle or dorsal distal radius. There was an 85% union incidence, improved carpal alignment and a low incidence of complications.
Iatrogenic Nerve Injuries of the Upper Extremity
Crowe, Christopher S. , Shin, Alexander Y. , Pulos, Nicholas , Shin, Alexander Y , Pulos, Nicholas

JBJS Reviews | February 1, 2023 | Volume: 11 | Issue: 1 | Pages: No page available

10.2106/jbjs.rvw.22.00161 Get It

» Iatrogenic nerve injuries may occur after any intervention of the upper extremity. » Causes of iatrogenic nerve lesions include direct sharp or thermal injury, retraction, compression from implants or compartment syndrome, injection, patient positioning, radiation, and cast/splint application, among others. » Optimal treatment of iatrogenic peripheral nerve lesions relies on early and accurate diagnosis. » Advanced imaging modalities (e.g., ultrasound and magnetic resonance imaging) and electrodiagnostic studies aid and assist in preoperative planning. » Optimal treatment of iatrogenic injuries is situation-dependent and depends on the feasibility of direct repair, grafting, and functional transfers.
The Role of Amputation and Myoelectric Prosthetic Fitting in Patients with Traumatic Brachial Plexus Injuries
Cantwell, Sean , Nelson, Andrew W. , Sampson, Brandon P. , Spinner, Robert J. , Bishop, Allen T. , Pulos, Nicholas , Shin, Alexander Y. , Cantwell, Sean R , Shin, Alexander Y , Bishop, Allen T , Pulos, Nicholas , Nelson, Andrew W.

Journal of Bone and Joint Surgery | June 23, 2022 | Volume: 104 | Issue: 16 | Pages: 1475-1482

10.2106/jbjs.21.01261 Get It

Background: A cohort of patients with traumatic brachial plexus injuries (BPIs) underwent elective amputation following unsuccessful surgical reconstruction or delayed presentation. The results of amputation with and without a myoelectric prosthesis (MEP) using nonintuitive controls were compared. We sought to determine the benefits of amputation, and whether fitting with an MEP was feasible and functional. Methods: We conducted a retrospective review of patients with BPI who underwent elective upper-extremity amputation at a single institution. Medical records were reviewed for demographics, injury and reconstruction details, amputation characteristics, outcomes, and complications. Prosthesis use and MEP function were assessed. The minimum follow-up for clinical outcomes was 12 months. Results: Thirty-two patients with BPI and an average follow-up of 53 months underwent elective amputation between June 2000 and June 2020. Among the cases were 18 transhumeral amputations, 12 transradial amputations, and 2 wrist disarticulations. There were 29 pan-plexus injuries, 1 partial C5-sparing pan-plexus injury, 1 lower-trunk with lateral cord injury, and 1 lower-trunk injury. Amputation occurred, on average, at 48.9 months following BPI and 36.5 months following final reconstruction. Ten patients were fitted for an MEP with electromyographic signal control from muscles not normally associated with the intended function (nonintuitive control). Average visual analog scale pain scores decreased post-amputation: from 4.8 pre-amputation to 3.3 for the MEP group and from 5.4 to 4.4 for the non-MEP group. Average scores on the Disabilities of the Arm, Shoulder and Hand questionnaire decreased post-amputation, but not significantly: from 35 to 30 for the MEP group and from 43 to 40 for the non-MEP group. Patients were more likely to be employed following amputation than they were before amputation. No patient expressed regret about undergoing amputation. All patients in the MEP group reported regular use of their prosthesis compared with 29% of patients with a traditional prosthesis. All patients in the MEP group demonstrated functional terminal grasp/release that they considered useful. Conclusions: Amputation is an effective treatment for select patients with BPI for whom surgical reconstruction is unsuccessful. Patients who underwent amputation reported decreased mechanical pain, increased employment rates, and a high rate of satisfaction following surgery. In amputees with sufficient nonintuitive electromyographic signals, MEPs allow for terminal grasp/release and are associated with high rates of prosthesis use. Level of Evidence: Therapeutic Level III . See Instructions for Authors for a complete description of levels of evidence.
CORR Insights®: Machine Learning Can be Used to Predict Function but Not Pain After Surgery for Thumb Carpometacarpal Osteoarthritis
Pulos, Nicholas , Pulos, Nicholas

Clinical Orthopaedics & Related Research | February 5, 2022 | Volume: 480 | Issue: 7 | Pages: 1285-1286

10.1097/corr.0000000000002139 Get It

Application of myoelectric elbow flexion assist orthosis in adult traumatic brachial plexus injury: a retrospective clinical study
Pulos, Nicholas , Berg, Catherine van den, Shin, Alexander Y., van den Berg, Catherine, Kaufman, Kenton R , Pulos, Nicholas , Berg, Catherine van den, Shin, Alexander Y.

Prosthetics & Orthotics International | November 13, 2021 | Volume: 45 | Issue: 6 | Pages: 521-525

10.1097/pxr.0000000000000046 Get It

Background: Adult traumatic brachial plexus injuries (BPIs) can result in severe impairment following penetrating wounds, falls, and motor vehicle accidents or other high-energy trauma. Objective: Quantify functional outcomes of adult patients with a BPI using a myoelectric orthosis to restore elbow flexion. Study design: Retrospective review. Methods: A clinic specializing in the BPI treatment at a large academic medical center tested nineteen adult patients with BPI. These patients had failed to achieve antigravity elbow flexion following their injury and observation or surgical reconstruction. They were provided a myoelectric elbow orthosis (MEO) if they had detectable electromyography signals. Results: There was significant improvement in strength and significant reductions in function and pain when using an MEO. Following initiation of the MEO, 12 of the 19 patients had clinical improvements in muscle strength, 15 patients showed improvement in their DASH, and 13 patients reported improvements in their Visual Analog Scale. Conclusion: The use of an MEO improves elbow flexion strength, increases function, and reduces pain in the majority of patients with BPI and inadequate elbow flexion following observation or surgical reconstruction.
Brachial Plexus Birth Injuries
Pulos, Nicholas , Shaughnessy, William J. , Spinner, Robert J. , Shin, Alexander Y. , Shin, Alexander Y , Pulos, Nicholas

JBJS Reviews | June 8, 2021 | Volume: 9 | Issue: 6 | Pages: No page available

10.2106/jbjs.rvw.20.00004 Get It

» The incidence of brachial plexus birth injury (BPBI) in the United States is declining and now occurs in <1 per 1,000 births. » The gold standard for predicting the need for early intervention remains serial examination. » Early treatment of BPBI with reconstructive surgery requires the ability to perform both interposition nerve grafting and nerve transfers. » Given the heterogeneity of lesions, the evidence is largely limited to retrospective comparative studies and case series.
Multifactorial Wrist Pain Treated with Tenotomy of Anomalous Flexor Carpi Radialis Brevis
Bernstein, Ethan , Leonardelli, Dominic , Pulos, Nicholas , Pulos, Nicholas

JBJS Case Connector | May 18, 2021 | Volume: 11 | Issue: 2 | Pages: No page available

10.2106/jbjs.cc.20.00102 Get It

Case: We present a case of a 33-year-old left hand–dominant/right hand–involved active duty Navy sailor woman with volar radial wrist pain. She underwent scaphoid cyst excision and bone grafting as well as tenotomy. Intraoperatively, she was noted to have a flexor carpi radialis brevis (FCRB) tendon that was transected. After surgery, her 1-year outcomes demonstrated range of motion improved equivalent with her contralateral side, her visual analogue scale (VAS) pain score had decreased to 1, and her QuickDASH and Patient-Rated Wrist Evaluation improved. Conclusions: Our case represents 1-year outcome after surgical release of a FCRB. Our patient's pain and functional scores exceeded the minimal clinically important difference.