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6050 citation(s) found for "Wu, Peter S".

O2‐06‐05: A voxel‐based morphometry study of volumetric MRI in familial Alzheimer's disease
Cash, David, Ryan, Natalie S. , Kinnunen, Kirsi M. , Yeatman, Tom, Malone, Ian B. , Raichle, Marc, Marcus, Daniel S., Ringman, John M. , Thompson, Paul , Salloway, Steven, Correia, Stephen , Villemagne, Victor L. , Mayeux, Richard , Fagan, Anne M. , Cairns, Nigel J., Buckles, Virginia, Moulder, Krista L., Ridgway, Gerard R. , Benzinger, Tammie L.S. , Koeppe, Robert A. , Jack, Clifford R. , Saykin, Andrew J. , Salloway, Steve , Johnson, Keith J. , Sperling, Reisa Anne , Schofield, Peter R. , Masters, Colin L. , Rowe, Christopher Cleon , Martins, Ralph N. , Brickman, Adam M. , Weiner, Michael W. , Bateman, Randall J. , Goate, Alison , Xiong, Chengjie , Morris, John C. , Rossor, Martin N. , Ourselin, Sébastien , Fox, Nick C.

Alzheimer's & Dementia | July 19, 2012 | Volume: 8 | Issue: 4S_Part_7 | Pages: No page available

10.1016/j.jalz.2012.05.658 Get It

P4‐153: Elevated PiB precedes dementia in autosomal‐dominant Alzheimer's disease: PiB, FDG and atrophy in the DIAN cohort
Raichle, Marc, Su, Yi , Marcus, Daniel S. , Ringman, John M. , Mayeux, Richard , Weiner, Michael W. , Fagan, Anne M. , Cairns, Nigel J. , Buckles, Virginia, Moulder, Krista L., Villemagne, Victor L. , Benzinger, Tammie L.S. , Blazey, Tyler , Koeppe, Robert A. , Jack, Clifford R. , Snyder, Abraham Z. , Johnson, Keith J. , Sperling, Reisa Anne , Thompson, Paul M. , Ghetti, Bernardino , Saykin, Andrew J. , Schofield, Peter R. , Masters, Colin L. , Rowe, Christopher Cleon , Fox, Nick C. , Brickman, Adam M. , Martins, Ralph N. , Mathis, Chester A. , Klunk, William E. , Bateman, Randall J. , Goate, Alison , Morris, John C.

Alzheimer's & Dementia | July 19, 2012 | Volume: 8 | Issue: 4S_Part_19 | Pages: No page available

10.1016/j.jalz.2012.05.1857 Get It

O2‐06‐02: FDG metabolism in the DIAN study of autosomal dominant Alzheimer's disease
Marcus, Daniel S. , Raichle, Marc, Correia, Stephen , Weiner, Michael W. , Fagan, Anne M. , Buckles, Virginia, Moulder, Krista L., Mayeux, Richard , Cairns, Nigel J. , Ringman, John M. , Salloway, Stephen , Johnson, Keith A. , Becker, John Alex , Koeppe, Robert A. , Benzinger, Tammie L.S. , Jack, Clifford R. , Thompson, Paul M. , Saykin, Andrew J. , Schofield, Peter R. , Rowe, Christopher Cleon , Fox, Nick C. , Brickman, Adam M. , Ghetti, Bernardino , Masters, Colin L. , Mathis, Chester A. , Bateman, Randall J. , Goate, Alison , Xiong, Chengjie , Martins, Ralph N. , Morris, John C. , Sperling, Reisa Anne

Alzheimer's & Dementia | July 19, 2012 | Volume: 8 | Issue: 4S_Part_7 | Pages: No page available

10.1016/j.jalz.2012.05.655 Get It

IC‐P‐020: A voxel‐based morphometry study of volumetric MRI in familial Alzheimer's disease
Ryan, Natalie S. , Yeatman, Tom, Malone, Ian B. , Raichle, Marc, Marcus, Daniel S. , Ringman, John M. , Salloway, Stephen , Correia, Stephen , Johnson, Keith A. , Villemagne, Victor L. , Mayeux, Richard , Weiner, Michael W. , Fagan, Anne M. , Cairns, Nigel J. , Buckles, Virginia, Moulder, Krista L., Cash, David M. , Ridgway, Gerard R. , Kinnunen, Kirsi M. , Benzinger, Tammie L.S. , Koeppe, Robert A. , Jack, Clifford R. , Thompson, Paul M. , Saykin, Andrew J. , Sperling, Reisa Anne , Schofield, Peter R. , Masters, Colin L. , Rowe, Christopher Cleon , Martins, Ralph N. , Brickman, Adam M. , Bateman, Randall J. , Goate, Alison , Xiong, Chengjie , Morris, John C. , Rossor, Martin N. , Ourselin, Sébastien , Fox, Nick C.

Alzheimer's & Dementia | July 19, 2012 | Volume: 8 | Issue: 4S_Part_1 | Pages: No page available

10.1016/j.jalz.2012.05.052 Get It

IC‐P‐032: Cross‐sectional cerebral volumetric differences and associations with estimated time to age‐at‐onset in familial Alzheimer's disease: Findings from the DIAN study
Leung, Kelvin K., Cardoso, Manuel, Malone, Ian B. , Yeatman, Tom, Nicholas, Jennifer M. , Raichle, Marcus E. , Marcus, Daniel, Ringman, John M. , Salloway, Stephen , Correia, Stephen , Sperling, Reisa, Villemagne, Victor L. , Mayeux, Richard , Weiner, Michael W. , Buckles, Virginia, Moulder, Krista L., Kinnunen, Kirsi M. , Cash, David M. , Liang, Yuying , Cardoso, Manuel, Modat, Marc , Benzinger, Tammie L.S. , Koeppe, Robert A. , Jack, Clifford R. , Thompson, Paul M. , Saykin, Andrew J. , Ghetti, Bernardino , Johnson, Keith J. , Schofield, Peter R. , Rowe, Christopher Cleon , Masters, Colin L. , Brickman, Adam M. , Martins, Ralph N. , Bateman, Randall J. , Goate, Alison , Morris, John C. , Rossor, Martin N. , Ourselin, Sébastien , Fox, Nick C.

Alzheimer's & Dementia | July 19, 2012 | Volume: 8 | Issue: 4S_Part_1 | Pages: No page available

10.1016/j.jalz.2012.05.064 Get It

O2‐06‐01: Disrupted functional connectivity in autosomal dominant Alzheimer's disease: Preliminary findings from the DIAN study
Chhatwal, Jasmeer P. , Johnson, Keith A. , Salloway, Stephen , Ringman, John M. , Marcus, Daniel S. , Correia, Stephen , Rowe, Christopher C., Mayeux, Richard , Weiner, Michael W. , Fagan, Anne M. , Cairns, Nigel J. , Xiong, Chengjie , Moulder, Krista L., Buckles, Virginia, Schultz, Aaron P. , Benzinger, Tammie L.S. , Jack, Clifford R. , Koeppe, Robert A. , Thompson, Paul M. , Saykin, Andrew J. , Schofield, Peter R. , Fox, Nick C. , Brickman, Adam M. , Mathis, Chester A. , Goate, Alison , Masters, Colin L. , Ghetti, Bernardino , Martins, Ralph N. , Bateman, Randall J. , Morris, John C. , Sperling, Reisa Anne

Alzheimer's & Dementia | July 19, 2012 | Volume: 8 | Issue: 4S_Part_7 | Pages: No page available

10.1016/j.jalz.2012.05.654 Get It

P1‐099: Developing a national institutional review board for neurodegenerative diseases
Khachaturian, Ara , Snyder, Peter J. , Carrillo, María C. , Knopman, David S.

Alzheimer's & Dementia | July 19, 2012 | Volume: 8 | Issue: 4S_Part_4 | Pages: No page available

10.1016/j.jalz.2012.05.375 Get It

P1‐015: Brain and hippocampal rates of atrophy in familial Alzheimer's disease mutation carriers: Preliminary findings from the DIAN study
Leung, Kelvin K., Cardoso, Manuel, Malone, Ian B. , Raichle, Marc, Marcus, Daniel, Ringman, John M. , Salloway, Stephen , Correia, Stephen , Sperling, Reisa, Villemagne, Victor L. , Mayeux, Richard , Weiner, Michael W. , Buckles, Virginia, Moulder, Krista L., Kinnunen, Kirsi M. , Cash, David M. , Liang, Yuying , Cardoso, Manuel, Modat, Marc , Benzinger, Tammie L.S. , Koeppe, Robert A. , Jack, Clifford R. , Thompson, Paul M. , Saykin, Andrew J. , Ghetti, Bernardino , Johnson, Keith J. , Schofield, Peter R. , Rowe, Christopher Cleon , Masters, Colin L. , Brickman, Adam M. , Martins, Ralph N. , Bateman, Randall J. , Goate, Alison , Morris, John C. , Rossor, Martin N. , Ourselin, Sébastien , Fox, Nick C.

Alzheimer's & Dementia | July 19, 2012 | Volume: 8 | Issue: 4S_Part_3 | Pages: No page available

10.1016/j.jalz.2012.05.290 Get It

Insignificant effect of secretin in rodent models of polycystic kidney and liver disease
Ye, Hong , Ward, Christopher J. , Chu, Jessica , Masyuk, Tatyana V. , Harris, Peter C. , Chow, Bkc , Torres, Vicente E. , Wang, Xiaofang , LaRusso, Nicholas F. , Harris, Peter C , Torres, Vicente E

American Journal of Physiology-Renal Physiology | July 19, 2012 | Volume: 303 | Issue: 7 | Pages: F1089-F1098

10.1152/ajprenal.00242.2012 | PMID 22811488 Get It

Polycystic kidney (PKD) and liver (PLD) diseases cause significant morbidity and mortality. A large body of evidence indicates that cyclic AMP plays an important role in their pathogenesis. Clinical trials of drugs that reduce cyclic AMP levels in target tissues are now in progress. Secretin may contribute to adenylyl cyclase-dependent urinary concentration and is a major agonist of adenylyl cyclase in cholangiocytes. To investigate the role of secretin in PKD and PLD, we have studied the expression of secretin and the secretin receptor in rodent models orthologous to autosomal recessive ( PCK rat) and dominant ( Pkd2−/WS25mouse) PKD; the effects of exogenous secretin administration to PCK rats, PCK rats lacking circulating vasopressin ( PCKdi/di), and Pkd2−/WS25mice; and the impact of a nonfunctional secretin receptor on disease development in Pkd2−/WS25:SCTR−/−double mutants. Renal and hepatic secretin and secretin receptor mRNA and plasma secretin were increased in both models, and secretin receptor protein was increased in the kidneys and liver of Pkd2−/WS25mice. However, exogenous secretin administered subcutaneously via osmotic pumps had minimal or negligible effects and the absence of a functional secretin receptor had no influence on the severity of PKD or PLD. Therefore, it is unlikely that by itself secretin plays a significant role in the pathogenesis of PKD and/or PLD.
P1‐057: Neuropsychiatric symptoms at baseline predict shorter time to severe dementia in a population‐based sample of incident Alzheimer's disease: The Cache County Dementia Progression Study
Rabins, Peter V., Schwartz, Sarah , Tschanz, JoAnn T. , Corcoran, Chris , Black, Betty S., Fauth, Elizabeth Braungart , Mielke, Michelle M. , Lyketsos, Constantine G.

Alzheimer's & Dementia | July 19, 2012 | Volume: 8 | Issue: 4S_Part_4 | Pages: No page available

10.1016/j.jalz.2012.05.333 Get It