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Bernhisel, Ashlie

https://orcid.org/0000-0002-6692-2281

Mayo Clinic

University of Utah

Citations 8

Program Director Perspectives on Global Ophthalmology Fellowships
Musser, John A., Damento, Gena M., Welk, Grant M., O’Banion, Jacquelyn A., Pettey, Jeff H. , Gilbert, Suzanne , Welk, Grant M. , Bernhisel, Ashlie , Musser, John A., O’Banion, Jacquelyn , O’Brien, Kieran Sunanda

Journal of Academic Ophthalmology | February 27, 2026 | Volume: 18 | Issue: 1 | Pages: No page available

10.62199/2475-4757.1334 Get It

Background: Eight Global Ophthalmology (GO) fellowship programs are available in the United States, and more than 30 U.S. GO fellows are now alumni. There are no standardized learning objectives for these programs, and fellows’ experiences vary widely between institutions. Purpose: To survey GO fellowship program directors in the United States to elucidate differences in learning objectives, duration of time abroad, funding sources, and other differences between GO fellowships. Methods: All program directors at all institutions with current GO fellowship programs in the United States were sent a 25-question questionnaire via email from October through December 2022. The questionnaire included distinct domains regarding the GO fellowship experience, care delivery, didactics, and best practices. Most questionnaire items were quantitative; 3 were qualitative. Responses to the quantitative and qualitative questions items were summarized descriptively. Results: All 10 program directors from the 8 GO fellowship programs that were current at the time of the survey participated. GO fellowship positions at most (88%) institutions were funded, in part, by the billing of care services provided by the fellows, with 50% of programs receiving supplemental funding from donations and 25% from nongovernmental organizations. Non-GO duties at the program home institutions constituted 29.5% of the time spent during the fellowships, on average. Policy advocacy occupies 2.3% of fellowship time, on average. Specific didactic topics covered in the GO programs and director perspectives on the pragmatic best practices for GO outreach varied considerably; however, inclusion of at least some public health topics and ethics appeared to be consistent among all of the programs. Conclusions: These findings provide insights into the landscape of GO fellowship programs in the United States, highlighting variations in funding, formal educational opportunities, and the allocation of time fellows spent working at the program home institution. Establishing standardized core competencies for fellows is recommended.
Analysis of Keratoconus-Related Phenotypes in Two Pcsk1 Mouse Models
Beatty, C. H., Cai, Jingwen, Yu, Hongfang, Sun, Jiong, Heo, Yejin, Baratz, Keith H. , Patel, SI, Estes, Amy, Kuo, Anthony N., Liu, Y, Beatty, Carol, Yu, Hongfang, Heo, Yejin, Bernhisel, Ashlie

Translational Vision Science & Technology | February 4, 2026 | Volume: 15 | Issue: 2 | Pages: 3

10.1167/tvst.15.2.3 Get It

The Ophthalmology Surgical Competency Assessment Rubric for penetrating keratoplasty
Shoukry, Mira , Rivkin, Angeline , Chan, Clara C., Grandin, Juan Carlos, Lotfi, Adriana C., Vanathi, Murugesan, Golnik, Karl C. , Rivkin, Angeline C, Bernhisel, Ashlie , Rivkin, Angeline C, Chan, Clara C. , Vanathi, Murugesan

Indian Journal of Ophthalmology | December 29, 2025 | Volume: 74 | Issue: 1 | Pages: 65-69

10.4103/ijo.ijo_1199_25 Get It

Purpose: Irreversible corneal blindness disproportionately affects low- and middle-income countries where there remains a critical demand for surgeons skilled in corneal transplantation. Penetrating keratoplasty (PK) is a critical skill for ophthalmologists, especially as it remains the most widely performed type of corneal transplant in these parts of the world. Tools to teach and assess trainees in corneal transplantation are needed to help standardize training internationally. Here, we present an Ophthalmology Surgical Competency Assessment Rubric (OSCAR) aimed at assessing the competence and progress of residents in PK. Methods: A team of cornea specialists developed a rubric for PK using previously published OSCARs as a template. The draft included 11 key steps of PK and six global indices, with a grading scale based on a modified Dreyfus model. The rubric was then reviewed for face and content validity by a panel of eight international experts using an iterative feedback process. The draft underwent multiple cycles of feedback and revisions until a consensus was reached among the authors and the international expert panel. Results: The rubric contains 11 essential steps and six global indices with descriptions of expected functioning at four levels of competency (novice, beginner, advanced beginner, and competent). Conclusions: This OSCAR for PK contributes to the global standardization of ophthalmology training, helping to meet the increasing demand for corneal transplant services with high-quality care for all.
Posterior Dislocation of Posterior Lamellar Corneal Graft with Viable Endothelial Cells
Israilevich, Rachel , Trejo‐Lopez, Jorge , Salomão, Diva R. , Israilevich, Rachel N , Trejo-Lopez, Jorge, Starr, Matthew R , Bernhisel, Ashlie , Starr, Matthew R.

RETINAL Cases & Brief Reports | October 14, 2025 | Volume: No volume available | Issue: No issue available | Pages: No page available

10.1097/icb.0000000000001806 Get It

Purpose: To present a case of a dislocated posterior lamellar graft into the vitreous cavity in an eye that was post pars plana vitrectomy. Methods: Retrospective case report Results: A middle-aged man underwent pars plana vitrectomy (PPV), pars plana lensectomy (PPL), and SSIOL fixation following a traumatic eye injury. The patient required subsequent Descemet stripping automated endothelial keratoplasty (DSAEK) for corneal edema, and the posterior lamellar graft was lost intraoperatively into the posterior segment. The graft was surgically retrieved one week later, followed by a successful placement of a new posterior lamellar graft. Histopathological examination of the retrieved graft after one week in the vitreous cavity revealed viable endothelial cells, a novel finding in a posteriorly dislocated DSAEK graft. The newly placed graft remained attached and healed well, with the patient achieving a visual acuity (VA) of 20/80 at three months post-operatively. Discussion: Posteriorly dislocated grafts may be suitable for transplantation to the corneal stroma following prompt retrieval from the vitreous cavity. Prompt retrieval and appropriate surgical techniques are critical for optimizing outcomes in such clinical scenarios.
Keratoconus in Sub-Saharan Africa: A Scoping Review
Rivkin, Angeline , Bernhisel, Ashlie , D'Souza, Haley S, Bernhisel, Ashlie A , D’Souza, Haley S. , Prokop, Larry J.

Cornea | August 6, 2025 | Volume: 44 | Issue: 11 | Pages: 1440-1449

10.1097/ico.0000000000003940 Get It

Purpose: To assess the prevalence, associated conditions, diagnostic and treatment modalities, and provider education regarding the diagnosis and management of keratoconus (KCN) in sub-Saharan Africa (SSA) based on the currently available body of literature. Methods: Peer-reviewed publications from any year and any language were included. The databases included Cochrane Database of Systematic Reviews, Embase, and Ovid. A separate search of African Journals Online was conducted using the same Medical Subject Heading (MeSH) terms as the database search. Additional publications were identified in the references during full-text extraction. The abstracts of all publications were evaluated by two reviewers. The full text was then examined by one reviewer for inclusion. A data extraction tool was used by a single reviewer to document the findings. Results: Sixty-two publications were included in data extraction. Fourteen countries in SSA were represented. Prevalence was reported in eight SSA countries and ranged from 0% to 2.8%. The highest prevalence of 1.2% was found in a cross-sectional study in Banjul, Gambia. Diagnosis in urban areas is often made using slit lamps, although some sites had access to keratometry and/or topography, whereas rural areas use penlight exams alone. Penetrating keratoplasty was reported as an available treatment in 14 manuscripts, glasses and hard contact lenses in 10, and corneal cross-linking in two. Publications discussing provider education reported a knowledge gap. Conclusions: There is a need for increased data on KCN in SSA to better inform public health policy to improve KCN patients’ access to care and quality of life.
The effect of patient age on some new and older IOL power calculation formulas
Sella, Ruti , Reitblat, Olga , Durnford, Kathryn M. , Pettey, Jeff H. , Olson, Randall J. , Hahn, Tara E., Bernhisel, Ashlie , Afshari, Natalie A. , Bernhisel, Ashlie A, Bernhisel, Ashlie A

Acta Ophthalmologica | December 29, 2023 | Volume: 102 | Issue: 5 | Pages: No page available

10.1111/aos.16621 Get It

AbstractPurposeTo assess the accuracy of intraocular lens (IOL) power calculation in different age groups using various IOL calculation formulas.MethodsData from 421 eyes of 421 patients ≥60 years old (ages: 60–69, n = 131; 70–74, n = 105; 75–84, n = 158 and ≥85, n = 27), who underwent uneventful cataract surgery with SN60WF IOL implantation at John A. Moran Eye Center, Salt Lake City, USA, were retrospectively obtained. The SD of the prediction error (PE), median and mean absolute PEs and the percentage of eyes within ±0.25, ±0.50, ±0.75 and ±1.00 D were calculated after constant optimizations for the following formulas: Barrett Universal II (BUII), Emmetropia Verifying Optical (EVO) 2.0, Haigis, Hoffer Q, Hoffer QST, Holladay 1, Kane, Radial Basis Function (RBF) 3.0 and SRK/T. Results were compared between the different age groups.ResultsPredictability rates within 0.25D were lower for the eldest age group compared with the other groups using the EVO 2.0 (33% vs. 37%–53%, p = 0.045), Kane (26% vs. 35%–50%, p = 0.034) and SRK/T (22% vs. 31%–49%, p = 0.002). Higher median absolute refractive errors for all formulas were observed in the oldest group [range: 0.39 D (Haigis, Hoffer QSR)–0.48 D (Kane)], followed by the youngest group [range: 0.30 D (RBF 3.0)–0.39 D (Holladay 1, SRK/T)] but did not reach statistical significance. No significant differences between the groups in the distribution parameter were seen.ConclusionCurrent IOL power calculation formulas may have variable accuracy for different age groups. This should be taken into account when planning cataract surgery to improve refractive outcomes.
Geographic Representation of Authorship in Ophthalmic Research from Low- and Middle-Income Countries
Caleon, Ramoncito L., Nziyomaze, Elie , Imaniriho, Jean Damascene, Manirakiza, Eric , Nsengiyumva, Emmanuel, Sharfi, Duaa, Bernhisel, Ashlie , Teshome, Tiliksew, O’Banion, Jacquelyn , Bernhisel, Ashlie A

Ophthalmic Epidemiology | December 14, 2023 | Volume: 31 | Issue: 5 | Pages: 478-487

10.1080/09286586.2023.2291802 Get It

Suture Fixation to Reduce Graft Detachment in Descemet Stripping Endothelial Keratoplasty
Witsberger, Emily , Oyemade, Kafayat A. , Rauen, Matthew P. , Baratz, Hannah , Bernhisel, Ashlie , Maguire, Leo J., Baratz, Keith H. , Witsberger, Emily M, Baratz, Hannah Q , Bernhisel, Ashlie A, Bernhisel, Ashlie A , Patel, Sanjay V.

Cornea | July 28, 2023 | Volume: 43 | Issue: 4 | Pages: 425-431

10.1097/ico.0000000000003349 Get It

Purpose: The aim of this study was to report the outcomes of graft fixation using interrupted, full-thickness sutures on graft detachment after Descemet stripping endothelial keratoplasty (DSEK). Methods: All DSEK procedures performed at Mayo Clinic, Rochester, MN, from 2015 through 2022 were retrospectively reviewed. Risk factors for graft detachment were defined as previous incisional glaucoma surgery, previous penetrating keratoplasty, or absence of the normal lens–capsule barrier. Cases were categorized into sutured, high-risk grafts; unsutured, high-risk grafts; and unsutured, low-risk grafts. The primary outcome was graft detachment, and secondary outcomes were early graft failure and graft clarity at 12 months after surgery. Results: Demographics between the high-risk groups were similar for sex and age at the time of surgery. Graft detachment occurred in 4 of 97 sutured, high-risk eyes (4.1%) and 24 of 119 unsutured high-risk eyes (20.2%) (P = 0.002). In comparison, graft detachment occurred in 18 of 181 unsutured low-risk eyes (9.9%). The incidence of early graft failure was 2.1%, 5.0%, and 3.3% and late graft failure by 12 months was 9.8%, 12.8%, and 4.2%, respectively. Conclusions: In eyes with high-risk factors for graft detachment, suture fixation of the graft in DSEK decreased graft detachment to a rate at least as low as that in low-risk eyes.