Back to Authors

Irastorza, Laura

Mayo Clinic

Palm Beach Digestive Associates Delray Beach FL

Citations 2

Effect of Caffeine on Colonic Manometry in Children
Mehta, Vijay, Hopson, Puanani , Irastorza, Laura, Rizvi, Syed Ahsan, Fernandez, Jenelle , Thomas, Jessina, Nabar, Shruti , Safder, Shaista , Rizvi, Syed Ahsan

Journal of Pediatric Gastroenterology and Nutrition | December 27, 2022 | Volume: 76 | Issue: 1 | Pages: 20-24

10.1097/mpg.0000000000003627 Get It

Objectives:Coffee and caffeinated products have been widely consumed for many centuries. Previous adult studies have suggested that both coffee and decaffeinated beverages induce colonic motility. However, no study has been conducted in pediatrics, and the role of caffeine alone in pediatric colonic motility needs to be explored.Methods:A prospective study of pediatric patients undergoing standard colonic motility testing that were able to consume caffeinated coffee, decaffeinated coffee, and caffeine tablet during colonic manometry. Patients who had a gastrocolonic reflex and high amplitude propagated contractions (HAPCs) in response to intraluminal administration of bisacodyl in the colon were included in the final analyses.Results:Thirty‐eight patients were recruited, 22 of which were excluded, 11 due to abnormal studies (no HAPC seen in response to intraluminal response to bisacodyl), and 11 due to inability to consume all study agents or complete the study. Sixteen patients met criteria for final analyses. Intracolonic bisacodyl produced a larger area under the curve (AUC) compared to all other agents. Caffeinated coffee resulted in a higher AUC, motility index (MI), and time to HAPC compared with decaffeinated coffee (P < 0.05). There was no significant difference between caffeinated coffee and caffeine tablet, or caffeine tablet and decaffeinated coffee.Conclusions:Caffeine is indeed a colonic stimulant; however, other components of caffeinated and non‐caffeinated beverages likely induce colonic response and require further evaluation for possible use as a colonic stimulant.
The Impact of COVID‐19 on Job Prospects and Educational Training for Pediatric Gastroenterology Fellows
Irastorza, Laura, Hopson, Puanani , Ta, Allison , Kemme, Sarah , Mallon, Daniel , Mallon, Daniel , Lee, Christine Kyuyoung

Journal of Pediatric Gastroenterology and Nutrition | January 6, 2021 | Volume: 72 | Issue: 4 | Pages: 514-519

10.1097/mpg.0000000000003037 Get It

ABSTRACTObjectives:The COVID‐19 pandemic has significantly affected graduate medical education with redistribution of trainees, altered clinical care, and decreased research. For graduating trainees, there remains concern that financial stability of health systems will affect the availability of new positions and hiring practices. This survey aims to evaluate the pandemic's impact from pediatric gastroenterology fellows’ perspectives.Methods:An anonymous survey was distributed by e‐mail from June 11 to July 1, 2020 to all North American pediatric gastroenterology and advanced training fellows. The survey was tailored for the fellows’ year of training including questions on education, clinical experience, research, and job outlook.Results:Of the 434 pediatric gastroenterology fellows, 145 completed the survey. Of all respondents, negative impact was reported in 52% on clinical training, 46% research projects, and 41% procedural confidence. A majority (93%) of third‐year respondents had a job contract signed at the time of the survey; however, 18% of those contracts were subsequently altered with 5 respondents having job contracts rescinded due to hiring freezes. Fifty‐four percent of first‐ and second‐year fellow respondents reported concern regarding finding a job with the majority being second‐year fellows (78%).Conclusions:The COVID‐19 pandemic continues to affect the medical system and healthcare professionals. This survey identified significant impact on job acquisition for graduating pediatric gastroenterology fellows and other critical components of training, which are likely applicable to other pediatric trainees. The survey results raise questions about potential strategies to improve medical education and job search success for graduating trainees.