Citations 3
Spray Cryotherapy Esophageal Consortium Consensus Recommendations for Liquid Nitrogen Spray Cryotherapy in Barrett's Esophagus and Esophageal Cancer Using a Modified Delphi Process
Shah, Tilak , Ansari, Zaid , Ahmad, Akram I. , Coyle, Walter , Greenwald, Bruce B., Kachaamy, Toufic , Kothari, Shivangi , Sharma, Neil , Smallfield, George , Thakkar, Shyam , Tsai, Franklin , Zhang, Han , Friedland, Shai , Mok, Shaffer , Sedarat, Alireza, Smith, Michael S. , Vashi, Pankaj G., Fukami, Norio , Mok, Shaffer , Smith, Michael , Willingham, Field F , Turshudzhyan, Alla , Kaul, Vivek , Greenwald, Bruce B., Fukami, Norio , Vargo, John Joseph , Willingham, Field F.
American Journal of Gastroenterology | August 26, 2025 | Volume: 121 | Issue: 7 | Pages: 1592-1599
INTRODUCTION: The study aimed to develop consensus recommendations for the safe and appropriate use of liquid nitrogen spray cryotherapy in Barrett's esophagus and esophageal cancer. METHODS: Statements were initially formulated and grouped into categories of indications, training, preprocedure, intraprocedure, and postprocedure recommendations, frequency/timing of repeat procedures, and contraindications. Two investigators assessed the strength of the evidence for each statement using Grading of Recommendations Assessment, Development, and Evaluation methodology. Nineteen experts were invited to participate in a modified Delphi process. For statements that received >80% agreement, minor iterative edits were performed until there was unanimous consensus. If a threshold of 80% agreement was not reached, the statement was modified based on feedback and included in the next Delphi round. Statements were rejected if no consensus was reached after 3 rounds. RESULTS: After 3 Delphi rounds, 41 of 42 statements were accepted either in their original version (n = 11) or after modification based on expert input (n = 30). DISCUSSION: Through a modified Delphi process, we developed expert and evidence-based consensus recommendations to guide safe and appropriate use of liquid nitrogen spray cryotherapy in Barrett's esophagus and esophageal cancer.
S1046 Predicting Histological Diagnosis After Endoscopic Submucosal Dissection With Demographic Characteristics and Endoscopic Lesion Characteristics: An Analysis of a Large Cohort in North America
Gudenkauf, Franciska J. , Aihara, Hiroyuki , Jue, Terry L., Munroe, Craig A., Bhatt, Amit , Kumta, Nikhil A. , Othman, Mohamed O. , Aadam, A. Aziz , Siegel, Amanda B. , Schlachterman, Alexander , Kowalski, Thomas E., Samarasena, Jason , Chang, Kenneth J. , Su, Bailey , Ujiki, Michael , Sharaiha, Reem Z. , Carr‐Locke, David L. , Facg, Tomizawa, Yutaka , Renteln, Daniel von , Karasik, Michael, Patel, Neej, Hanada, Yuri , Song, Louis Wong Kee, Friedland, Shai , Sethi, Amrita , Ngamruengphong, Saowanee , Group, Gastric ESD Study, Bhatt, Amit , Ferri, Lorenzo Edwin , Draganov, Peter V. , Yang, Dennis J. , Grimm, Ian S. , DeWitt, John M. , Bechara, Robert , Fukami, Norio , Nishimura, Makoto , Laszkowska, Monika , Wang, Andrew , Hwang, Joo Ha , Group, Gastric ESD Study
American Journal of Gastroenterology | October 24, 2021 | Volume: 116 | Issue: 1 | Pages: S496-S496
Full-thickness resection device (FTRD) for treatment of upper gastrointestinal tract lesions: the first international experience
Khashab, Mouen A., Sharaiha, Reem Z. , Hajifathalian, Kaveh , Ichkhanian, Yervant , Dawod, Qais, Schmidt, Arthur , Glaser, Nicholas, Vosoughi, Kia , Templeton, Adam W. , Samarasena, Jason , Chehade, Nabil El Hage , Lee, John G., Chang, Kenneth J. , Mizrahi, Meir, Barawi, Mohammed, Irani, Shayan , Friedland, Shai , Korc, Paul , Aadam, A. Aziz , Kowalski, Thomas E., Smallfield, George , Ginsberg, Gregory G. , Kumta, Nikhil A. , Tang, Shou-jiang, Naga, Yehia M. , Amateau, Stuart K. , Kasmin, Franklin, Goetz, Martin , Seewald, Stefan , Kumbhari, Vivek , Ngamruengphong, Saowanee , Mahdev, Srihari, Mukewar, Saurabh , Sampath, Kartik, Carr‐Locke, David L. , Khashab, Mouen A. , Meining, Alexander , Diehl, David L. , Grimm, Ian S. , James, Theodore , Al‐Haddad, Mohammad , Fukami, Norio , Lajin, Michael
Endoscopy International Open | September 22, 2020 | Volume: 08 | Issue: 10 | Pages: E1291-E1301
Abstract Background and study aims The Full-Thickness Resection Device (FTRD) provides a novel treatment option for lesions not amenable to conventional endoscopic resection techniques. There are limited data on the efficacy and safety of FTRD for resection of upper gastrointestinal tract (GIT) lesions. Patients and methods This was an international multicenter retrospective study, including patients who had an endoscopic resection of an upper GIT lesion using the FTRD between January 2017 and February 2019. Results Fifty-six patients from 13 centers were included. The most common lesions were mesenchymal neoplasms (n = 23, 41 %), adenomas (n = 7, 13 %), and hamartomas (n = 6, 11 %). Eighty-four percent of lesions were located in the stomach, and 14 % in the duodenum. The average size of lesions was 14 mm (range 3 to 33 mm). Deployment of the FTRD was technically successful in 93 % of patients (n = 52) leading to complete and partial resection in 43 (77 %) and 9 (16 %) patients, respectively. Overall, the FTRD led to negative histological margins (R0 resection) in 38 (68 %) of patients. A total of 12 (21 %) mild or moderate adverse events (AEs) were reported. Follow-up endoscopy was performed in 31 patients (55 %), on average 88 days after the procedure (IQR 68–138 days). Of these, 30 patients (97 %) did not have any residual or recurrent lesion on endoscopic examination and biopsy, with residual adenoma in one patient (3 %). Conclusions Our results suggest a high technical success rate and an acceptable histologically complete resection rate, with a low risk of AEs and early recurrence for FTRD resection of upper GIT lesions.