Lesnick, Timothy G.
https://orcid.org/0000-0002-4126-5924
Mayo Clinic
Department of Quantitative Health Sciences
Citations 211
Thrombogenic microvesicles and white matter hyperintensities in postmenopausal women
Raz, Limor , Jayachandran, Muthuvel , Tosakulwong, Nirubol , Lesnick, Timothy G. , Wille, Samantha, Murphy, Matthew C. , Senjem, Matthew L. , Gunter, Jeffrey L. , Vemuri, Prashanthi , Miller, Virginia M. , Kantarci, Kejal , Jack, Clifford R. , Vemuri, Prashanthi , Senjem, Matthew L , Kantarci, Kejal
Neurology | February 14, 2013 | Volume: 80 | Issue: 10 | Pages: 911-918
A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11
Siddiq, Afshan , Chen, Gary K., Lindström, Sara, Eccles, Diana , Millikan, Robert C., Michailidou, Kyriaki , Beckmann, Lars , Aittomäki, Kristiina , Apicella, Carmel, Investigators, Australian Breast Cancer Tissue Bank, Baglietto, Laura , Bandera, Elisa V. , Beckmann, Matthias W. , Berg, Christine D. , Blomqvist, Carl , Brauch, Hiltrud , Brinton, Louise A. , Bui, Minh , Buring, Julie E. , Campa, Daniele , Carpenter, Jane, Chang‐Claude, Jenny, Chen, Constance, Clavel-Chapelon, Françoise, Cox, Angela , Cross, Simon S. , Czene, Kamila , Deming, Sandra L., Diasio, Robert B. , Diver, W. Ryan , Dunning, Alison M. , Durcan, Lorraine , Ekici, Arif B. , Fasching, Peter A. , Study, Familial Breast Cancer, Fejerman, Laura , Figueroa, Jonine D. , Flesch‐Janys, Dieter, Gaudet, Mia M., Gerty, Susan M. , Rodriguez‐Gil, Jorge L. , Giles, Graham G. , Gils, Carla H. van , Graham, Nikki , Greco, Dario , Hankinson, Susan E. , Hartmann, Arndt, Hein, Rebecca, Heinz, Judith , Hoover, Robert N. , Hu, Jennifer J. , Huntsman, Scott , Irwanto, Astrid , Jacobs, Kevin B. , John, Esther M. , Justenhoven, Christina , Kolonel, Laurence N. , Coetzee, Gerhard A. , Lathrop, Mark, Lee, I‐Min , Lesnick, Timothy G. , Lichtner, Peter , Liu, Jianjun , Lund, Eiliv , Makalic, Enes , Martin, Nicholas G. , McLean, Catriona , Meijers‐Heijboer, Hanne , Meindl, Alfons , Miron, Penelope , Montgomery, Grant W. , Müller‐Myhsok, Bertram , Nickels, Stefan , Nyante, Sarah J. , Olswold, Curtis, Overvad, Kim , Palli, Domenico , Park, Daniel J. , Palmer, Julie R. , Peto, Julian , Rahman, Nazneen , Rivadeneira, Fernando , Schmutzler, Rita K. , Slager, Susan, Southey, Melissa C. , Stevens, Kristen N., Sinn, Hans‐Peter , Ross, Eric A. , Ríboli, Elio , Schumacher, Fredrick R. , Severi, Gianluca , Stone, Jennifer , Sund, Malin , Tapper, William , Thun, Michael J., Travis, Ruth C. , Turnbull, Clare , Uitterlinden, André G. , Waisfisz, Quinten , Wang, Zhaoming , Weaver, JoEllen , Schulz-Wendtland, Rüdiger, Nevanlinna, Heli , Easton, Douglas F., Hunter, David J. , Henderson, Brian E., García‐Closas, Montserrat , Kraft, Peter , Haiman, Christopher A. , Vachon, Celine M. , Zheng, Wei , Purrington, Kristen S. , Couch, Fergus J. , Stram, Daniel O. , Rhie, Suhn K. , Ambrosone, Christine B. , Amiano, Pilar , Investigators, Australian Breast Cancer Tissue Bank, Bernstein, Leslie , Bui, Minh , Buys, Saundra S. , Chasman, Daniel I. , Study, Familial Breast Cancer, Feigelson, Heather Spencer , Fletcher, Olivia , Godwin, Andrew K. , Hall, Per N , Hankinson, Susan E. , Hopper, John L. , Ingles, Sue A. , Isaacs, Claudine , Kaaks, Rudolf , Marchand, Loı̈c Le , Lee, Adam M. , Meindl, Alfons , Monroe, Kristine R. , Pathak, Harsh B. , Pharoah, Paul D.P. , Schmidt, Daniel F. , Press, Michael F. , Ridker, Paul M. , dos‐Santos‐Silva, Isabel , Wang, Xianshu , Wilkens, Lynne R. , Berg, David Van Den , Zheng, Wei , Ziegler, Regina G. , Ziv, Elad , Chanock, Stephen Jacob , Vachon, Celine M. , Nevanlinna, H , Giles, Graham G , Eccles, Diana , John, Esther M , Palli, Domenico , Southey, Melissa C , Martin, Nicholas G , Sinn, Peter , Travis, Ruth C , Wang, Zhaoming , Dunning, Alison M , Cox, Angela , García-Closas, Montserrat , Severi, Gianluca , Makalic, Enes , Ekici, Arif B , Michailidou, Kyriaki , Palmer, Julie R , Kraft, Peter , Zheng, Wei , Figueroa, Jonine D , Nyante, Sarah , Czene, Kamila , Stone, Jennifer , Riboli, Elio , Sund, Malin , Baglietto, Laura , Purrington, Kristen S , Mclean, Catriona , Brauch, Hiltrud , Liu, Jing , Bandera, Elisa V.
Human Molecular Genetics | September 14, 2012 | Volume: 21 | Issue: 24 | Pages: 5373-5384
P1‐122: Effect of lifestyle activities on Alzheimer's biomarkers and cognition
Lesnick, Timothy G. , Przybelski, Scott A. , Roberts, Rosebud O., Lowe, Val J. , Gunter, Jeffrey L. , Petersen, Ronald C. , Vemuri, Prashanthi , Knopman, David S. , Kantarci, Kejal , Senjem, Matthew L. , Boeve, Bradley F. , Jack, Clifford R.
Alzheimer's & Dementia | July 19, 2012 | Volume: 8 | Issue: 4S_Part_4 | Pages: No page available
O3‐12‐04: Rates of PIB accumulation do plateau
Wiste, Heather J. , Weigand, Stephen D. , Lowe, Val J. , Lesnick, Timothy G. , Senjem, Matthew L. , Gunter, Jeffrey L. , Petersen, R.G., Jack, Clifford R. , Vemuri, Prashanthi , Knopman, David S. , Pankratz, V. Shane , Boeve, Bradley F. , Senjem, Matthew L
Alzheimer's & Dementia | July 19, 2012 | Volume: 8 | Issue: 4S_Part_12 | Pages: No page available
Large-scale replication and heterogeneity in Parkinson disease genetic loci
Sharma, Manu , Aasly, Jan , Annesi, Grazia , Brice, Alexis , Broeckhoven, Christine Van , Bozi, Maria , Crosiers, David , Clarke, Carl E , Facheris, Maurizio , Farrer, Matthew J. , Garraux, Gaëtan , Gispert, Suzana, Auburger, Georg , Vilariño‐Güell, Carles , Hicks, Andrew A. , Hattori, Nobutaka , Jeon, Beom S., Lesage, Suzanne , Lill, Christina M. , Lin, Juei-Jueng, Lynch, Timothy , Lichtner, Peter , Lang, Anthony E. , Jasińska‐Myga, Barbara, Mellick, George D. , Morrison, Karen , Opala, Grzegorz, Pramstaller, Peter P. , Pichler, Irene , Park, Sung Sup , Quattrone, Aldo , Ross, Owen A. , Stockton, Joanne , Satake, Wataru , Silburn, Peter A., Theuns, Jessie , Tan, Eng-King, Tomiyama, Hiroyuki , Uitti, Ryan J. , Wirdefeldt, Karin , Xiromerisiou, Georgia , Yueh, Kuo-Chu, Zhao, Yi , Gasser, Thomas , Maraganore, Demetrius M. , Krüger, Rejko , Boyle, R.S, Sellbach, A, Siebert, G., Pickut, Barbara , Engelborghs, Sebastiaan , Meeus, Bram, Deyn, Peter Paul De, Cras, Patrick , Agid, Yves, Anheim, Mathieu , Bonnet, A-M, Broussolle, E. , Corvol, Jean‐Christophe , Destée, A., Durif, F., Lesage, Suzanne , Lohmann, Ebba , Pollak, Pierre, Rascol, Olivier , Tison, François , Viallet, François, Amouyel, Philippe , Loriot, Marie‐Anne , Mutez, Eugénie , Duflot, Aurélie , Legendre, Jean-Philippe, Waucquier, Nawal, Schulte, Claudia , Klein, Christine , Djarmati, Ana, Hagenah, Johann, Lohmann, Katja , Hilker, Rüdiger, Loo, Simone van de, Tsimourtou, Vaïa, Ralli, Styliani, Kountra, Persa, Patramani, Gianna, Vogiatzi, Cristina, Hattori, Nobutaka, Yoshino, Hiroyo , Li, Yuanzhe, Imamichi, Yoko, Gibson, J. Mark , Ialongo, Tàmara, Brighina, Laura , Corradi, B., Piolti, Roberto, Tarantino, Patrizia, Kłodowska-Duda, Gabriela, Boczarska‐Jedynak, Magdalena , Tan, Eng King, Olson, Lars, Westerlund, Marie, Sydow, Olof , Puschmann, Andreas , Lin, J-J , J, Eric Ahlskog, Lesnick, Timothy G. , Rocca, Walter A. , Checkoway, Harvey , Westenberger, Ana , Ioannidis, John P. A. , Bertram, Lars , Hadjigeorgiou, Georgios M. , Mok, Vincent , Rogaeva, Ekaterina A. , Stefanis, Leonidas , Toda, Tatsushi , Wszołek, Zbigniew K. , O’Sullivan, John D. , Sutherland, Greg T. , Dissanayaka, Nadeeka N. , Borg, Michael , Damier, Philippe , Dürr, Alexandra , Tranchant, Christine , Vidailhet, Marie , Tzourio, Christophe , Rieß, Olaf , Berg, Daniela , Dardiotis, Efthimios , Funayama, Manabu , Valente, Enza Maria , Ferraris, Alessandro , Dallapiccola, Bruno , Annesi, Ferdinanda , Belin, Andrea Carmine , Olson, Lars, Galter, Dagmar , Nilsson, Christer C. , Andrade, Mariza de , Lang, Anthony E , Ross, Owen A , Puschmann, Andreas , Klein, Christine , Amouyel, Philippe , Corvol, Jean-Christophe , Mutez, Eugénie , Schulte, Claudia , Brice, Alexis
Neurology | July 12, 2012 | Volume: 79 | Issue: 7 | Pages: 659-667
A limited role for DJ1 in Parkinson disease susceptibility
Maraganore, Demetrius M. , Wilkes, Kristen, Lesnick, Timothy G. , Strain, Kari J., Rocca, Walter A. , Bower, James H., Ahlskog, J. Eric , Lincoln, S., Farrer, Matthew J. , Andrade, Mariza de
Neurology | May 13, 2012 | Volume: 63 | Issue: 3 | Pages: 550-553
Prosthetic joint infection in solid organ transplant recipients: a retrospective case‐control study
Vergidis, Paschalis , Lesnick, Timothy G. , Kremers, Walter K. , Razonable, Raymund R. , Vergidis, Paschalis , Kremers, Walter K
Transplant Infectious Disease | January 20, 2012 | Volume: 14 | Issue: 4 | Pages: 380-386
10.1111/j.1399-3062.2011.00708.x
Abstract:BackgroundThe clinical features and outcome of prosthetic joint infection (PJI) among solid organ transplant (SOT) recipients have not been characterized. We performed a retrospective, matched case‐control study to examine potential risk factors.MethodsWe reviewed cases ofPJIamong transplant recipients who were evaluated at the Mayo Clinic between 1989 and 2009. Cases were matched to non‐infected controls based on transplant type, prosthetic joint type, and order of organ transplantation/joint implantation.ResultsAmong 367 patients with both a joint prosthesis and anSOT, there were 12 cases of infection in those receiving immunosuppression. These occurred in 8 renal recipients, 3 liver recipients, and 1 heart transplant recipient. Six subjects had hip and 6 had knee arthroplasty infections. The observed time to prosthesis failure ranged from 0.5 to 148 months after implantation. Gram‐positive bacteria (staphylococci and streptococci) caused the infection in 8 subjects. Two cases were caused by nontuberculous mycobacteria, whereas the remaining 2 cases were culture‐negative in the setting of antimicrobial use. We did not find a statistically significant association between obesity, diabetes mellitus, or antimicrobial prophylaxis (given in the setting of immunosuppression) and development ofPJI. A marginal association was seen betweensurgical site infectionand the risk ofPJI; however, this did not reach statistical significance.ConclusionIn our series, infection was mainly caused by gram‐positive bacterial pathogens, similar to the commonly encountered organisms in the immunocompetent host, although opportunistic pathogens were also isolated.
Common Breast Cancer Susceptibility Loci Are Associated with Triple-Negative Breast Cancer
Stevens, Kristen N., Vachon, Celine M. , Slager, Susan, Lesnick, Timothy G. , Olswold, Curtis, Fasching, Peter A. , Miron, Penelope , Eccles, Diana , Carpenter, Jane, Winqvist, Robert , Brauch, Hiltrud , Schmidt, Marjanka K. , Cox, Angela , Cross, Simon S. , Sawyer, Elinor J. , Hartmann, Arndt, Beckmann, Matthias W. , Schulz-Wendtland, Rüdiger, Ekici, Arif B. , Tapper, William , Gerty, Susan M. , Durcan, Lorraine , Graham, Nikki , Hein, Rebecca, Nickels, Stephan, Flesch‐Janys, Dieter, Heinz, Judith , Sinn, Hans‐Peter , Konstantopoulou, Irene , Pectasides, Dimitrios , Dimopoulos, Athanasios M., Clarke, Christine L. , Balleine, Rosemary L. , Fredericksen, Zachary, Diasio, Robert B. , Ross, Eric A. , Weaver, JoEllen , Rüdiger, Thomas , Dünnebier, Thomas, Ademuyiwa, Foluso O. , Kulkarni, Swati , Pylkäs, Katri , Jukkola‐Vuorinen, Arja , Ko, Yon‐Dschun, Limbergen, Erik Van, Janssen, Hilde, Peto, Julian , Fletcher, Olivia , Giles, Graham G. , Baglietto, Laura , Verhoef, Senno, Tomlinson, Ian , Kosma, Veli‐Matti , Greco, Dario , Blomqvist, Carl , Irwanto, Astrid , Liu, Jianjun , Blows, Fiona M., Dawson, Sarah‐Jane , Margolin, Sara , Mannermaa, Arto, Martin, Nicholas G. , Montgomery, Grant W. , Lambrechts, Diether , dos‐Santos‐Silva, Isabel , Severi, Gianluca , Hamann, Ute, Easton, Douglas F., Chang‐Claude, Jenny , Yannoukakos, Drakoulis , Nevanlinna, Heli , Dimopoulos, Meletios Α. , Purrington, Kristen S. , Lambrechts, Diether , Vachon, Celine M. , Lee, Adam M. , Godwin, Andrew K. , Ambrosone, Christine B. , Fostira, Florentia , Dimopoulos, Athanasios M., Fountzilas, George , Olson, Janet E. , Pathak, Harsh B. , Försti, Asta , Beesley, Jonathan , Mannermaa, Arto, Pharoah, Paul D.P. , Wang, Xianshu , Couch, Fergus J. , Nevanlinna, H , Lambrechts, Diether , Giles, Graham G , Eccles, Diana , Dimopoulos, Meletios A , Konstantopoulou, Irene , Martin, Nicholas G , Sinn, Peter , Lambrechts, Diether , Cox, Angela , Schmidt, Marjanka K , Severi, Gianluca , Ekici, Arif B , Ademuyiwa, Foluso O , Pylkäs, Katri , Yannoukakos, Drakoulis , Baglietto, Laura , Fletcher, Olivia , Purrington, Kristen S , Brauch, Hiltrud , Sawyer, Elinor J , Liu, Jing
Cancer Research | August 15, 2011 | Volume: 71 | Issue: 19 | Pages: 6240-6249
Abstract Triple-negative breast cancers are an aggressive subtype of breast cancer with poor survival, but there remains little known about the etiologic factors that promote its initiation and development. Commonly inherited breast cancer risk factors identified through genome-wide association studies display heterogeneity of effect among breast cancer subtypes as defined by the status of estrogen and progesterone receptors. In the Triple Negative Breast Cancer Consortium (TNBCC), 22 common breast cancer susceptibility variants were investigated in 2,980 Caucasian women with triple-negative breast cancer and 4,978 healthy controls. We identified six single-nucleotide polymorphisms, including rs2046210 (ESR1), rs12662670 (ESR1), rs3803662 (TOX3), rs999737 (RAD51L1), rs8170 (19p13.1), and rs8100241 (19p13.1), significantly associated with the risk of triple-negative breast cancer. Together, our results provide convincing evidence of genetic susceptibility for triple-negative breast cancer. Cancer Res; 71(19); 6240–9. ©2011 AACR.
Empowerment of Women and Its Association with the Health of the Community
Varkey, Prathibha, Kureshi, Sarah , Lesnick, Timothy G.
Journal of Women's Health | January 20, 2010 | Volume: 19 | Issue: 1 | Pages: 71-76
α-Synuclein, pesticides, and Parkinson disease
Brighina, Laura , Frigerio, Roberta , Schneider, N., Lesnick, Timothy G. , Cunningham, John M. , Farrer, Matthew J. , Lincoln, S., Checkoway, Harvey , Rocca, Walter A. , Maraganore, Demetrius M. , Andrade, Mariza de
Neurology | March 6, 2008 | Volume: 70 | Issue: 16_part_2 | Pages: 1461-1469