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Frigerio, Roberta

0000-0002-4417-290X

Mayo Clinic

Endeavor Health

Citations 5

Genetic Evidence for a Dual and Opposing Effect of alpha-Synuclein Expression in Preclinical Versus Clinical Parkinson's Disease (P05.059)
Markopoulou, Katerina , Ahlskog, J. Eric , Anderson, Kari, Armasu, Sebastian M. , Cunningham, Julie L. , Frigerio, Roberta , Maraganore, Demetrius M. , Biernacka, Joanna M. , Chung, Sun Ju

Neurology | December 7, 2023 | Volume: 80 | Issue: 7_supplement | Pages: No page available

10.1212/wnl.80.7_supplement.p05.059 Get It

Genetic Evidence for a Dual and Opposing Effect of alpha-Synuclein Expression in Preclinical Versus Clinical Parkinson's Disease (IN2-1.003)
Markopoulou, Katerina , Ahlskog, J. Eric , Anderson, Kari, Armasu, Sebastian M. , Cunningham, Julie L. , Frigerio, Roberta , Maraganore, Demetrius M. , Biernacka, Joanna M. , Chung, Sun Ju

Neurology | December 7, 2023 | Volume: 80 | Issue: 7_supplement | Pages: No page available

10.1212/wnl.80.7_supplement.in2-1.003 Get It

Alpha‐synuclein repeat variants and survival in Parkinson's disease
Armasu, Sebastian M. , Anderson, Kari, Frigerio, Roberta , Aasly, Jan , Annesi, Grazia , Bentivoglio, Anna Rita , Brighina, Laura , Chartier‐Harlin, Marie‐Christine , Goldwurm, Stefano , Jasińska‐Myga, Barbara, Jeon, Beom Seok , Kim, Yun Joong , Krüger, Rejko , Lesage, Suzanne , Markopoulou, Katerina , Mellick, George D. , Morrison, Karen , Puschmann, Andreas , Tan, Eng‐King , Crosiers, David , Broeckhoven, Christine Van , Wirdefeldt, Karin , Maraganore, Demetrius M. , Chung, Sun Ju , Biernacka, Joanna M. , Hadjigeorgiou, Georgios M. , Theuns, Jessie , Wszołek, Zbigniew K. , Elbaz, Alexis , Puschmann, Andreas

Movement Disorders | February 27, 2014 | Volume: 29 | Issue: 8 | Pages: 1053-1057

10.1002/mds.25841 Get It

ABSTRACT Objectives To determine whether α‐synuclein dinucleotide repeat (REP1) genotypes are associated with survival in Parkinson's disease (PD). Methods Investigators from the Genetic Epidemiology of Parkinson's Disease Consortium provided REP1 genotypes and baseline and follow‐up clinical data for cases. The primary outcome was time to death. Cox proportional hazards regression models were used to assess the association of REP1 genotypes with survival. Results Twenty‐one sites contributed data for 6,154 cases. There was no significant association between α‐synuclein REP1 genotypes and survival in PD. However, there was a significant association between REP1 genotypes and age at onset of PD (hazard ratio: 1.06; 95% confidence interval: 1.01‐1.10; P value = 0.01). Conclusions In our large consortium study, α‐synuclein REP1 genotypes were not associated with survival in PD. Further studies of α‐synuclein's role in disease progression and long‐term outcomes are needed. © 2014 International Parkinson and Movement Disorder Society
α-Synuclein, pesticides, and Parkinson disease
Brighina, Laura , Frigerio, Roberta , Schneider, N., Lesnick, Timothy G. , Cunningham, John M. , Farrer, Matthew J. , Lincoln, S., Checkoway, Harvey , Rocca, Walter A. , Maraganore, Demetrius M. , Andrade, Mariza de

Neurology | March 6, 2008 | Volume: 70 | Issue: 16_part_2 | Pages: 1461-1469

10.1212/01.wnl.0000304049.31377.f2 Get It

Education and occupations preceding Parkinson disease
Frigerio, Roberta , Sanft, Kevin R. , Peterson, B. J., Bower, James H., Ahlskog, J. Eric , Grossardt, Brandon R. , Maraganore, Demetrius M. , Rocca, Walter A. , Elbaz, Alexis , Andrade, Mariza de , Grossardt, Brandon R

Neurology | July 12, 2006 | Volume: 65 | Issue: 10 | Pages: 1575-1583

10.1212/01.wnl.0000184520.21744.a2 Get It