Alladi, Suvarna
https://orcid.org/0000-0002-0372-9572
Mayo Clinic
National Institute of Mental Health and Neurosciences
Citations 2
Emerging directions in tauopathy research
Wildsmith, Kristin R., Alladi, Suvarna, Bertucci, Taylor, Bowles, Kathryn R. , Boxer, Adam, Brummet, Jennifer, DeVos, Sarah L., Diaz, Kristophe , Duff, Karen, Duran‐Aniotz, Claudia, Farrell, Kurt, Fontana, Igor C., Franzmeier, Nicolai, Frost, Bess, Petrucelli, Leonard, Rexach, Jessica, Reyderman, Larisa, Rommel, Amy, Bohórquez, Sandra M. Sanabria, Schöll, Michael, Schneider, Anja, Silva, Rohan de , Snyder, Heather M. , VandeVrede, Lawren, Varga, Andrew W, Vogel, Jacob W., Yeh, Felix L. , Yoo, Andrew S., Carrillo, Maria C., Duff, Karen , Bertucci, Taylor , Mahinrad, Simin , Buée, Luc , Alladi, Suvarna , Boche, Delphine , DeVos, Sarah L. , Dreyer, Anna J. , Duran‐Aniotz, Claudia , Durrant, Claire S. , Farrell, Kurt , Fontana, Igor C. , Franzmeier, Nicolai , Frost, Bess , Horie, Kanta , Kaňovský, Petr , Kao, Aimee W. , Mahinrad, Simin , Malpetti, Maura , Morris, Huw R. , Palleis, Carla , Petrucelli, Leonard , Rexach, Jessica E. , Reyderman, Larisa, Rowe, James B. , Bohórquez, Sandra Sanabria , Sato, Chihiro , Schneider, Anja , VandeVrede, Lawren , Varga, Andrew W. , Vogel, Jacob W. , Yoo, Andrew S.J. , Carrillo, María C.
Alzheimer's & Dementia | June 22, 2026 | Volume: 22 | Issue: 6 | Pages: No page available
Abstract The Tau Global Conference 2025, hosted by the Alzheimer's Association, CurePSP, and the Rainwater Charitable Foundation, convened international experts from academia, industry, government, and philanthropy to explore advances and challenges in tauopathy research. The meeting highlighted progress across tau biology, including emerging models of tau regulation, degradation, and propagation; advances in biomarker development for the diagnosis and staging of tauopathies; and evolving therapeutic strategies targeting diverse aspects of tau pathophysiology. Discussions also emphasized the importance of cross‐sector collaboration, and global initiatives to address disparities in tau research. This report synthesizes key insights from the conference and underscores the critical role of interdisciplinary, biomarker‐driven, and globally inclusive approaches in accelerating the translation of tau research into effective clinical applications.
White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): Knowledge gaps and opportunities
Alber, Jessica , Alladi, Suvarna , Barton, David A., Bell, Joanne M., Berman, Sara E., Biessels, Geert Jan , Bos, Isabelle , Bowman, Gene L. , Brai, Emanuele , Callahan, Brandy L. , Corriveau, Roderick A. , Fossati, Silvia , Gottesman, Rebecca F. , Gustafson, Deborah , Hachinski, Vladimir , Hayden, Kathleen M. , Helman, Alex M., Hughes, Timothy M. , Isaacs, Jeremy D. , Jefferson, Angela L. , Kern, Silke , Kwon, Jay C., Lee, Athene , Lockhart, Samuel N. , Murray, Anne M. , Osborn, Katie E. , Price, Brittani R. , Rhodius‐Meester, Hanneke , Rondeau, Jacqueline A., Rosen, Allyson , Scholtzova, Henrieta , Shaaban, C. Elizabeth , Silva, Nárlon Cássio Boa Sorte , Snyder, Heather M. , Swardfager, Walter , Troen, Aron M. , Vemuri, Prashanthi , Wallin, Anders , Wellington, Cheryl L. , Xie, Sharon X. , Hainsworth, Atticus H. , Vemuri, Prashanthi , Gottesman, Rebecca F , Hainsworth, Atticus H , Bae, Hee‐Joon , Beckett, Laurel , Biessels, Geert Jan , Black, Sandra E. , Brickman, Adam M. , Johnson, Sterling C. , Kapasi, Alifiya , Kukolja, Juraj , Power, Melinda C. , Rosene, Douglas L , Schneider, Julie A. , Veluw, Susanne J. van , Wilcock, Donna M.
Alzheimer's & Dementia: Translational Research & Clinical Interventions | April 8, 2019 | Volume: 5 | Issue: 1 | Pages: 107-117
Abstract White matter hyperintensities (WMHs) are frequently seen on brain magnetic resonance imaging scans of older people. Usually interpreted clinically as a surrogate for cerebral small vessel disease, WMHs are associated with increased likelihood of cognitive impairment and dementia (including Alzheimer's disease [AD]). WMHs are also seen in cognitively healthy people. In this collaboration of academic, clinical, and pharmaceutical industry perspectives, we identify outstanding questions about WMHs and their relation to cognition, dementia, and AD. What molecular and cellular changes underlie WMHs? What are the neuropathological correlates of WMHs? To what extent are demyelination and inflammation present? Is it helpful to subdivide into periventricular and subcortical WMHs? What do WMHs signify in people diagnosed with AD? What are the risk factors for developing WMHs? What preventive and therapeutic strategies target WMHs? Answering these questions will improve prevention and treatment of WMHs and dementia.