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Cowl, Clayton T.

https://orcid.org/0000-0001-6714-0081

Mayo Clinic

Mayo Clinic

Citations 11

Adding employment status in the medical record demonstrates its importance as a social determinant of health
Breeher, Laura E. , Westphal, Samantha, Green, Tammy, Abbas, Alzhraa Salah , Cowl, Clayton T. , Abbas, Alzhraa Salah , Breeher, Laura , Westphal, Samantha, Green, Tammy

JAMIA Open | October 1, 2025 | Volume: 8 | Issue: 5 | Pages: No page available

10.1093/jamiaopen/ooaf108 Get It

Abstract Objective To share findings of a quality improvement initiative to capture employment status in the electronic medical record (EMR) to mitigate the potential impact of work loss on the health of patients by utilizing the results to identify eligible individuals for resources to assist return-to-work efforts. Materials and Methods Patients self-identified employment status through a structured new social determinants of health (SDOH) question within the EMR. An electronic outreach campaign was developed to provide information via the patient portal detailing services within healthcare and the community that could benefit the patients. Results Over the course of 12 months, 2059 patients were identified from the employment SDOH question. Resources to support stay at work and return to work efforts were provided to patients through an automated electronic portal campaign with 87% of patients reading the message and 7% engaging with a healthcare return to work case manager. Discussion Loss of employment has detrimental impacts on individual and population health. Most EMRs do not capture information on employment status. Adding this simple question identified individuals with potential gaps in SDOH, and in this case allowed specific resources to be shared with patients with an illness or injury that was acutely impacting work. Conclusion Medical center decision makers and EMR programmers should consider adding employment status as a social determinant of health.
Impacts of “Race-neutral" GLI-Global Prediction Equations in Occupational Health
Townsend, Mary C., Harber, Philip , Cowl, Clayton T.

American Journal of Respiratory and Critical Care Medicine | May 11, 2025 | Volume: 211 | Issue: Supplement_1 | Pages: A7202-A7202

10.1164/ajrccm.2025.211.abstracts.a7202 Get It

Abstract RATIONALE: The American Thoracic Society (ATS) recently recommended using “race-neutral” GLI-Global prediction equations to interpret spirometry results. However, the unintended consequences for workers have not been fully evaluated. METHODS: We analyzed the impact of adopting GLI-Global on 24 hypothetical subjects, using on-line calculators to examine the effects on 1) larger vs. smaller predicted values; 2) Black, Southeast Asian, Northeast Asian, and White races; and 3) 80%, 100%, and 120% of race-specific predicted forced vital capacity (FVC). RESULTS: Race-specific predicted FVCs decline by group: White > NE Asian > SE Asian > Black, with a difference of 0.84 L between Blacks and Whites. GLI-Global Predicteds are midway between Blacks’ and Whites’. Workers at 80% of race-specific Predicted change the most when GLI-Global is employed: Blacks and SE Asians show declining %Predicted values and Z-scores and an increase in FVCs<LLN, while Whites and NE Asians show increasing %Predicted and Z-scores and a decrease in FVCs<LLN. CONCLUSIONS: Choice of prediction equation for use in occupational health practice differentially affects individuals in several groups: a) When fixed criteria are used for job placement and retention decisions, Black and SE Asian persons may be particularly adversely affected, while Whites and NE Asians will more likely exceed the fixed criteria; b) When fixed criteria are used for disability decisions, Black and SE Asian persons may look increasingly disabled, while White and NE Asian persons may now fail to qualify for disability; and c) Disparate effects are most prominent for persons with lung function measures in the lower portion of the normal range. Since occupational criteria are unlikely to change quickly, clinicians and policymakers should consider the real-world implications of mandating or recommending specific equations.
Mn RETAIN: An early intervention model to identify and support stay at work and return to work for injured and ill employees across industries
Breeher, Laura E. , Omondi, Nancy, Westphal, Samantha, Idossa, Lensa, Green, Tammy, Connell, John, Zabel, Erik W., Trihey, Jakki, Carlson, Amy J., Apaloo, Rita, Sherrard, Cameron, Shahriar, Arif, Valappil, Usha, Pratt, Akiatu, Liedke, Angela, Carlson, Paul J. , Kohlnhofer, Stacy, Jerde, Laura, Cowl, Clayton T. , Breeher, Laura , Westphal, Samantha, Idossa, Lensa, Green, Tammy, Shahriar, Arif, Pratt, Akiatu, Carlson, Pam

WORK: A Journal of Prevention, Assessment & Rehabilitation | December 14, 2024 | Volume: 80 | Issue: 3 | Pages: 1415-1424

10.1177/10519815241290331 Get It

Background The Minnesota Retaining Employment and Talent After Injury and Illness Network (MN RETAIN) is a randomized controlled study designed to evaluate early interventions promoting workforce retention among workers in Minnesota. The study compares a cohort receiving increased support for stay at work and return to work (SAW/RTW) services from healthcare organizations and resources through workforce development to a control cohort provided solely a list of SAW/RTW resources within the state they can access on their own. Objective This manuscript aims to describe the design of the MN RETAIN Phase 2 study and experience to date including enrollment. Target enrollment for Phase 2 of MN RETAIN is 3200 workers with approximately half receiving SAW/RTW services from a Return-to-Work Case Manager (RWTCM) who is embedded within the healthcare team. MN RETAIN is structured to be accessible to all workers within the state, with a focus on equity and reaching historically underserved populations. Methods Phase 2 of the RETAIN model expanded the focus from the southeast region of MN to state-wide coverage. Enrollment and services were designed to acquire a large enough cohort to reach adequate statistical power to detect differences in disability costs and rates of SAW/RTW in participating study subjects. Impact analysis of RETAIN will be performed by the federal evaluator at a future date. Results Characteristics of enrolled participants to date are summarized as well as considerations for sustainability of the program upon study completion. Conclusions To date, the study has reached diverse workers from throughout the state of MN to provide assistance with SAW/RTW.
Abstract 15101: Return-to-Work for Patients in High-Risk Professions Diagnosed With a Sudden Death-Predisposing Genetic Heart Disease
Kulkarni, Veda, Tobert, Kathryn E. , Cowl, Clayton T. , MacIntyre, Ciorsti, Giudicessi, John R. , Ackerman, Michael J. , Bos, J. Martijn

Circulation | June 15, 2023 | Volume: 146 | Issue: Suppl_1 | Pages: No page available

10.1161/circ.146.suppl_1.15101 Get It

Introduction: Sudden cardiac arrest (SCA) and death (SCD) are the most serious sequelae of many genetic heart diseases (GHDs). Increased awareness of this has led to increased detection in employment screenings. For patients in high-risk jobs, premature and potentially unnecessary termination from their profession, rather than “Return-to-Work (RTW),” has become an undesired consequence of this awareness. The objective of this study is to evaluate the outcomes of patients with GHDs in high-risk professions who were allowed to RTW. Methods: We performed a retrospective review of 3,641 working-age patients referred for evaluation of a potential GHD between 6/2000-12/2021 to identify those either in or being recruited into a high-risk profession. A profession was defined as “high-risk” if it is safety-sensitive or required regular medical evaluations. Charts were reviewed for medical history, RTW decision making, and breakthrough cardiac events (BCEs). Results: Overall, 33 patients [(0.9%); 3 females (9%); mean age at diagnosis 25 ± 15 years] had been either put on hold from their high-risk job (n = 15; 45%) or disqualified as a recruit (18; 55%) prior to our evaluation due to their GHD diagnosis. This included 15 military, 10 pilots, 6 law enforcement and first responders, and 2 commercial driver license professionals and recruits. Most patients were diagnosed with Long QT syndrome (n = 23; 70%). After treatment initiation, 14 (93%) professionals and 16 (89%) recruits received physician RTW approval while 3 (9%) patients did not receive RTW approval due to disease severity and/or unwillingness to initiate treatment. Of the remaining 14 professionals that received physician RTW approval, 4 (29%) were not allowed to return to their jobs, while 14/16 recruits (88%) were not permitted to start their career. None of the RTW-approved patients had a BCE after evaluation (160.7 follow-up years). Conclusions: Patients with GHDs in high-risk professions are often terminated due to perceived SCA/SCD risk. However, within our small cohort, the risk of BCEs in optimally treated patients was low. This data suggests that the certification process of individuals in these high-risk and safety-sensitive occupations should be further examined and potentially modified.
Elementary Overview of Heavy Metals
Jannetto, Paul J. , Cowl, Clayton T.

Clinical Chemistry | March 22, 2023 | Volume: 69 | Issue: 4 | Pages: 336-349

10.1093/clinchem/hvad022 Get It

AbstractBackgroundExposure to heavy metals is common as a result of environmental contamination of air, water, and soil as well as accumulation in food, tobacco, herbal medicines, and occupational contact. However, clinically relevant toxicity is much less prevalent. Toxic effects, when they occur, may present with non-specific symptoms, resulting in a very large differential for clinicians to consider.ContentArsenic, cadmium, lead, and mercury are four heavy metals with no biological role in humans. However, these metals are commonly used in industrial applications and consumer products. Since these elements are not biodegradeable, their potential toxic effects may be long-lasting within the environment. These heavy metals have the potential to accumulate in vital organs such as the brain, heart, and kidney where they may disrupt normal cellular functioning and if exposures are repetitive or of high concentration, toxicity may result.SummaryThe objective of this review is to provide an overview of arsenic, cadmium, lead, and mercury physical properties, common sources of exposure, basic toxicokinetics and health effects, and to review clinical guidelines and treatment strategies. Acute and chronic symptoms and recommended laboratory biomarker testing are also discussed.
Reduced Diffusing Capacity in Humidifier Disinfectant-Associated Asthma Versus Typical Asthma: A Retrospective Case Control Study
Pak, Chuiyong , Cowl, Clayton T. , Kim, Jin Hyoung , Kang, Byung Ju , Lee, Taehoon , Jegal, Yangjin , Won, Seung , Kim, Yangho , Ra, Seung Won

Journal of Korean Medical Science | November 1, 2022 | Volume: 37 | Issue: 44 | Pages: No page available

10.3346/jkms.2022.37.e319 Get It

U.S. Occupational Historical Perspective on Race and Lung Function
Townsend, Mary C., Cowl, Clayton T.

American Journal of Respiratory and Critical Care Medicine | May 3, 2022 | Volume: 206 | Issue: 6 | Pages: 789-790

10.1164/rccm.202203-0565le Get It

Health assessment of commercial drivers: a meta-narrative systematic review
Dabrh, Abd Moain Abu , Firwana, Belal , Cowl, Clayton T. , Steinkraus, Lawrence W., Murad, M. Hassan , Abu Dabrh, Abd Moain, Prokop, Larry J. , Murad, M Hassan , Abu Dabrh, Abd Moain

BMJ Open | March 6, 2014 | Volume: 4 | Issue: 3 | Pages: e003434

10.1136/bmjopen-2013-003434 Get It

Background Motor vehicle accidents associated with commercial driving are an important cause of occupational death and impact public safety. Objectives We summarise the evidence regarding the type, prevalence and impact of medical conditions discovered during health assessment of commercial drivers. Evidence review We conducted a systematic review of multiple electronic databases and made a manual search for relevant studies that enrolled commercial drivers in any country and reported the outcomes of health assessment carried out in the context of commercial driving through November 2012. Data were extracted by a pair of independent reviewers and synthesised using a metanarrative approach. Results We identified 32 studies of moderate methodological quality enrolling 151 644 commercial drivers (98% men). The prevalence of multiple health conditions was high (sleep disorders 19%, diabetes 33%, hypertension 23% and obesity 45%). Some conditions, such as sleep disorders and obesity, were linked to increased risk of crashes. Evidence on several other highly relevant medical conditions was lacking. Cost-effectiveness data were sparse. Conclusions Several medical conditions are highly prevalent in commercial drivers and can be associated with increased risk of crashes, thus providing a rationale for health assessment of commercial drivers.
HYPERMANGANESEMIA, HEREDITARY HEMORRHAGIC TELANGIECTASIA, BRAIN ABSCESS: THE HEPATIC CONNECTION
Boeve, B. F., Cowl, Clayton T. , Ellison, Jay W., Kamath, Priyatham, Swanson, Karen L., Kumar, Naveen

Neurology | September 29, 2008 | Volume: 71 | Issue: 14 | Pages: 1118-1119

10.1212/01.wnl.0000326959.44088.e0 Get It

Brain metal concentrations in chronic liver failure patients with pallidal T1 MRI hyperintensity
Klos, Kevin J., Ahlskog, J. Eric , Kumar, Neeraj , Cambern, Sarah J, Butz, James J. , Mf, Burritt, Fealey, Robert D., Cowl, Clayton T. , Parisi, J. E., Josephs, Keith A.

Neurology | December 13, 2006 | Volume: 67 | Issue: 11 | Pages: 1984-1989

10.1212/01.wnl.0000247037.37807.76 Get It