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Shunkwiler, Sara M.

Mayo Clinic

University of Nebraska Medical Center

Citations 2

The apheresis management of patients undergoing transplantation: a concise review
Simmons, Sierra C. , Adamski, Jill , Berg, Mary , Biller, Elizabeth, Fang, Deanna C., Ipe, Tina S. , Shunkwiler, Sara M., Zhao, Yong, Baron, Beverly W. , Pham, Huy P. , AABB, on behalf of the Apheresis Subsection of the, Ipe, Tina S , Pham, Huy P , AABB, on behalf of the Apheresis Subsection of the

Transfusion | January 31, 2019 | Volume: 59 | Issue: 5 | Pages: 1863-1869

10.1111/trf.15153 Get It

The management of anticoagulation in patients undergoing therapeutic plasma exchange: A concise review
Shunkwiler, Sara M., Wool, Geoffrey D. , Ipe, Tina S. , Fang, Deanna C., Biller, Elizabeth, Treml, Angela , Weiss, John, Baron, Beverly W. , Berg, Mary, AABB, On behalf of the Therapeutic Apheresis Subsection of the, Wool, Geoffrey , Ipe, Tina S , Baron, Beverly W , Pham, Huy P. , AABB, On behalf of the Therapeutic Apheresis Subsection of the

Journal of Clinical Apheresis | October 26, 2017 | Volume: 33 | Issue: 3 | Pages: 371-379

10.1002/jca.21592 Get It

We surveyed multiple apheresis centers represented by the authors for their clinical approach to the management of anticoagulation issues during therapeutic plasma exchange (TPE). We present the results of their practices and a review of the pertinent literature. As plasma is removed during TPE, replacement with all or partial non‐plasma‐containing fluids (eg, 5% albumin) may lead to significant changes in hemostasis. These changes are amplified in patients who are receiving anticoagulation. We discuss various anticoagulants as well as the monitoring and adjustment of anticoagulation before, during, and after TPE. No single guideline can be applied, but rather, patients must be monitored individually, taking into account their often complex clinical conditions and medication profiles.