Citations 64
P3–194: Age‐specific incidence rates of Alzheimer's disease in family members participating in the NIA‐LOAD genetics study
Bird, Thomas D., Farlow, Martin R. , Graff‐Radford, Neill, Rosenberg, Roger N., Schaid, Daniel J. , Bennett, Jeffrey, Davis, Barb, Faber, Kelley , Garland, Connie, Horner, Kimberly , Kistler, Dana, Kuntz, Karen M. , Levitch, Denise, Norton, Joanne, Pluff, Lindsay, Reyes, Dolly, Rumbaugh, Malia, Sena, Amanda, Torneten, Sarah, Weamer, Elise A., Group, NIA LOAD Study, Mayeux, Richard, Vardarajan, Badri Narayan , Bennett, David A. , Boeve, Bradley F. , Foroud, Tatiana , Goate, Alison , Graff‐Radford, Neill, Ottman, Ruth , Sweet, Robert A. , Tsuang, Debby W. , Group, NIA LOAD Study, Mayeux, Richard
Alzheimer's & Dementia | October 9, 2013 | Volume: 9 | Issue: 4S_Part_15 | Pages: No page available
P1–063: Association of TREM2 variants with Alzheimer's disease in African‐Americans: For the Alzheimer's Disease Genetics Consortium (ADGC)
Reitz, Christiane , Larson, Eric B. , Graff‐Radford, Neill, Evans, Denis A., Jager, Philip L. De , Ertekin‐Taner, Nilüfer , Cantwell, Laura B., Fallin, Danielle, Hall, Kathleen, Byrd, Goldie S. , Haines, Jonathan L. , Pericak‐Vance, Margaret A. , Schellenberg, Gerard, Mayeux, Richard , Jun, Gyungah , Naj, Adam Christian , Vardarajan, Badri Narayan , Wang, Weixin , Graff‐Radford, Neill, Crane, Paul K. , Buxbaum, Joseph D. , Logue, Mark W. , Green, Robert C. , Manly, Jennifer J. , Lunetta, Kathryn L. , Kamboh, M. Ilyas , López, Oscar L. , Bennett, David A. , Goate, Alison , Kukull, Walter A. , Foroud, Tatiana , Farrer, Lindsay A.
Alzheimer's & Dementia | October 9, 2013 | Volume: 9 | Issue: 4S_Part_4 | Pages: No page available
O2–03–01: Validation of the Alzheimer's Prevention Initiative Composite Cognitive Test Score
Ayutyanont, Napatkamon , Hendrix, Suzanne , Fleisher, Adam , Caselli, Richard J. , Monsell, Sarah E. , Tariot, Pierre N. , Reiman, Eric M. , Langbaum, Jessica B. S. , Chen, Kewei , Kukull, Walter A. , Bennett, David A.
Alzheimer's & Dementia | October 9, 2013 | Volume: 9 | Issue: 4S_Part_8 | Pages: No page available
GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment
Rietveld, Cornelius A. , Medland, Sarah E. , Derringer, Jaime , Esko, Tõnu , Martín, Nicolás W., Westra, Harm-Jan , Shakhbazov, Konstantin, Abdellaoui, Abdel , Albrecht, Eva, Alizadeh, Behrooz Z. , Amin, Najaf , Baumeister, Sebastian E. , Benke, Kelly S. , Bielak, Lawrence F. , Boatman, Jeffrey A. , Boyle, Patricia A. , Davies, Gail , Leeuw, Christiaan de , Eklund, Niina, Evans, Daniel S. , Ferhmann, Rudolf, Fischer, Krista , Gieger, Christian , Gjessing, Håkon K. , Hägg, Sara , Harris, Jennifer R. , Hayward, Caroline , Jacobsson, Bo , Joshi, Peter K. , Jugessur, Astanand , Kaakinen, Marika , Kanoni, Stavroula , Karjalainen, Juha, Kolčić, Ivana , Kristiansson, Kati , Kutalik, Zoltán , Lahti, Jari , Lee, Sang , Lin, Peng, Lind, Penelope A. , Lohman, Kurt, Loitfelder, Marisa, McMahon, George, Marques‐Vidal, Pedro , Meirelles, Osorio , Milani, Lili , Myhre, Ronny , Nuotio, Marja-Liisa , Oldmeadow, Christopher , Petrovic, Katja, Peyrot, Wouter J. , Polašek, Ozren , Quaye, Lydia, Reinmaa, Eva, Rice, John P. , Rizzi, Thais S., Schmidt, Helena , Schmidt, Reinhold, Smith, Albert V. , Smith, Jennifer A. , Terracciano, Antonio , Loos, Matthijs J. H. M. van der, Vitart, Véronique , Völzke, Henry , Wellmann, Jürgen , Yu, Lei , Zhao, Wei , Allïk, Jüri , Bandinelli, Stefania , Bastardot, François , Beauchamp, Jonathan , Bennett, David A. , Berger, Klaus, Bültmann, Ute , Campbell, Harry, Chabris, Christopher F., Cherkas, Lynn, Chung, Mina K. , Cucca, Francesco , Jager, Philip L. De , Neve, Jan-Emmanuel De, Deary, Ian J. , Dedoussis, George , Deloukas, Panos , Dimitriou, Maria , Eiríksdóttir, Guðný , Elderson, Martin F., Eriksson, Johan G. , Evans, David M. , Faul, Jessica D. , Ferrucci, Luigi , Garcia, Melissa E., Grönberg, Henrik , Guðnason, Vilmundur , Harris, Tamara B., Hastie, Nicholas D. , Hernández, Dena , Hoffmann, Wolfgang , Hofman, Adriaan, Holle, Rolf , Holliday, Elizabeth G., Hottenga, Jouke‐Jan , Illig, Thomas, Järvelin, Marjo‐Riitta , Kähönen, Mika , Kaprio, Jaakko , Kirkpatrick, Robert M. , Kowgier, Matthew , Latvala, Antti , Lawlor, Debbie A. , Lehtimäki, Terho , Li, Jingmei , Lichtenstein, Paul , Lichtner, Peter , Liewald, David C. , Madden, Pamela A. F., Magnusson, Patrik K. E. , Mäkinen, Tomi E., Masala, Marco , McGue, Matt , Mielck, Andreas, Miller, Michael B., Montgomery, Grant W. , Mukherjee, Sutapa , Nyholt, Dale R. , Oostra, Ben A., Palmer, Lyle J. , Palotie, Aarno , Perola, Markus, Peyser, Patricia A. , Preisig, Martin , Räikkönen, Katri , Rivadeneira, Fernando , Rudan, Igor , Rustichini, Aldo , Sarin, Antti-Pekka, Schlessinger, David, Scott, Rodney J. , Snieder, Harold , Pourcain, Beaté St , Starr, John M. , Sul, Jae Hoon , Surakka, Ida , Svento, Rauli , Teumer, Alexander , Study, The LifeLines Cohort, Tiemeier, Henning , Rooij, Frank J.A. van , Wagoner, David R. Van , Vartiainen, Erkki , Viikari, Jorma , Vollenweider, Péter , Vonk, Judith M. , Waeber, Gérard , Weir, David R. , Wichmann, H.‐Erich , Widén, Elisabeth , Willemsen, Gonneke , Wright, Alan F., Davey-Smith, George, Franke, Lude , Groenen, Patrick J. F. , Hofman, Albert , Johannesson, Magnus , Kardia, Sharon L. R., Krueger, Robert F., Laibson, David, Martin, Nicholas G. , Meyer, Michelle N., Posthuma, Daniëlle , Thurik, Roy , Timpson, Nicholas J. , Uitterlinden, André G. , Duijn, Cornelia M. van , Visscher, Peter M. , Benjamin, Daniel J. , Cesarini, David , Koellinger, Philipp , Bennett, David A. , Smith, George Davey , Meyer, Michelle N. , Westra, Harm-Jan , Yang, Jian , Agrawal, Arpana , Barnard, John , Holzapfel, Christina M. , Ibrahim‐Verbaas, Carla A. , Ingelsson, Erik , Lin, Peng, Liu, Ching‐Ti , Tanaka, Toshiko , Attia, John , Berger, Klaus, Bierut, Laura Jean , Boomsma, Dorret I , Andrade, Mariza de , Hall, Per N , Harris, Juliette , Heath, Andrew C. , Hofman, Adriaan, Holliday, Elizabeth G., Iacono, William G. , Launer, Lenore J. , Mäkinen, Tomi E., Metspalu, Andres , Palotie, Aarno V. , Penninx, Brenda W.J.H. , Raitakari, Olli Tuomas , Realo, Anu , Ring, Susan M. , Ripatti, Samuli , Salomaa, Veikko , Study, The LifeLines Cohort, Wilson, James Fox , Conley, Dalton , Davey-Smith, George, Smith, Jennifer A , Hottenga, Jouke-Jan , Martin, Nicholas G , Posthuma, Danielle , St Pourcain, Beate , Medland, Sarah E , Li, Jingmei , Teumer, Alexander , van Duijn, Cornelia M , Smith, Albert V , Ferrucci, Luigi , Davey Smith, George , Vonk, Judith M , Kanoni, Stavroula , Surakka, Ida
Science | May 31, 2013 | Volume: 340 | Issue: 6139 | Pages: 1467-1471
Genetic College Many genomic elements in humans are associated with behavior, including educational attainment. In a genome-wide association study including more than 100,000 samples, Rietveld et al. (p. 1467 , published online 30 May; see the Perspective by Flint and Munafò ) looked for genes related to educational attainment in Caucasians. Small genetic effects at three loci appeared to impact educational attainment.
P4‐126: Genome‐wide exploration of DNA methylation in the aging brain and its relation to Alzheimer's disease
Jager, Philip L. De , Srivastava, Gyan , Eaton, Matthew L. , Zou, Fangeng, Song, High, Younkin, Curtis, Younkin, Steven G., Ertekin‐Taner, Nilüfer , Bernstein, B, Meissner, Alexander , Chibnik, Lori Beth , Keenan, Brendan T , Kellis, Manolis , Bennett, David A.
Alzheimer's & Dementia | July 19, 2012 | Volume: 8 | Issue: 4S_Part_18 | Pages: No page available
O1‐09‐01: CTNNA3, CAPRIN2 and SPG20 are significantly associated with Alzheimer's disease in preliminary analyses of a genome‐wide association study in African‐Americans
Reitz, Christiane , Hall, Kathleen, Evans, Denis A., Ertekin‐Taner, Nilüfer , Fallin, Danielle, Pericak‐Vance, Margaret A. , Haines, Jonathan L. , Mayeux, Richard , Schellenberg, Gerard D. , Manly, Jennifer J. , Bennett, David A. , Buxbaum, Joseph D. , Kamboh, M. Ilyas , Foroud, Tatiana , Goate, Alison , Farrer, Lindsay A.
Alzheimer's & Dementia | July 19, 2012 | Volume: 8 | Issue: 4S_Part_3 | Pages: No page available
Genotype patterns atPICALM, CR1, BIN1, CLU, andAPOEgenes are associated with episodic memory
Barral, Sandra , Bird, Thomas D., Goate, Alison , Farlow, MR, Diaz‐Arrastia, Ramon , Bennett, David A. , Graff-Radford, N. R., Stern, Yaakov , Ott, Jürg , Mayeux, Richard , Kowall, Neil W. , Williamson, Jennifer, Santana, Vincent, Schmechel, Donald E., Gaskel, Peter, Farlow, Martin R. , Faber, Kelley, Horner, Kelly, Growdon, John H., Blacker, Deborah , Tanzi, Rudolph E. , Kuntz, Karen M. , Norgaard, Lindsay, Larson, Nathan, Kistler, Dana, Parfitt, Francine, Haddow, Jenny, Silverman, Jeremy M. , Beeri, Michal Schnaider , Sano, Mary , Wang, Joy , Lally, Rachel, Johnson, Nancy, Mesulam, Marcel, Weıntraub, Sandra , Bigio, Eileen H. , Kaye, Jeffery, Kramer, Patricia, Payne-Murphy, Jessica, Jacobs, Holli, Chang, Joon, Arends, Danielle, Harrell, Lindy, Bartzokis, George, Cummings, Jeffery L., Lu, Po H. , Toland, Usha, Smith, Charles , Brickhouse, Alise, Trojanowski, John Q. , DeKosky, Steven T. , Weamer, Elise A., Chui, Helena C., Varpetian, Arousiak, Rosenberg, Roger N., Schellenberg, Gerard D. , Raskind, Murray A. , Rumbaugh, Malia, Nickel, Kate, Norton, Joanne, Levitch, Denise, Grant, B., Coats, Mary A., Levey, Allen, Rosen, Ami, Anosike, Ezinna, Bennett, David A. , Wilson, Robert S. , Boeve, Bradley F. , Sweet, Robert A. , Wilson, R. J. , Foroud, Tatiana , Green, Robert C. , Farrer, Lindsay A. , Ghetti, Bernardino , Prentice, Heather A. , Hyman, Bradley T. , Larson, Nathan, Kaye, Jeffery, Deerlin, Vivianna M. Van , Wood, Elisabeth McCarty , Davis, Barbara Allen , Morris, John A. , Stern, Yaakov , Goate, Alison M , Diaz-Arrastia, Ramon
Neurology | April 27, 2012 | Volume: 78 | Issue: 19 | Pages: 1464-1471
O3‐03‐02: Composite cognitive endpoints with improved power to detect presymptomatic Alzheimer's disease treatment effects in APOE4 carriers: Findings from the Alzheimer's prevention initiative
Hendrix, Suzanne , Ayutyanont, Napatkamon , Tariot, Pierre N. , Fleisher, Adam , Caselli, Richard J. , Langlois, Carolyn, Reiman, Eric M. , Langbaum, Jessica B. S. , Chen, Kewei , Bennett, David A.
Alzheimer's & Dementia | August 1, 2011 | Volume: 7 | Issue: 4S_Part_14 | Pages: No page available
P1‐281: Multilocus genotype pattern at PICALM, CLU and APOE genes is associated with episodic memory in the NIA‐LOAD/NCRAD study
Bird, Thomas D., Farlow, Martin R. , Graff‐Radford, Neill, Wilson, Robert , Mayeux, Richard , Bennett, David A. , Boeve, Bradley F. , Diaz‐Arrastia, Ramon , Foroud, Tatiana , Goate, Alison , Graff‐Radford, Neill, Sweet, Robert A.
Alzheimer's & Dementia | August 1, 2011 | Volume: 7 | Issue: 4S_Part_6 | Pages: No page available
Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
Aisen, Paul, Beckett, Laurel , Bennett, David A. , Craft, Suzanne , Fagan, Anne M. , Iwatsubo, Takeshi , Jack, Clifford R. , Kaye, Jeffrey , Montine, Thomas J. , Park, Denise C. , Reiman, Eric M. , Siemers, Eric , Stern, Yaakov , Yaffe, Kristine , Carrillo, María C. , Thies, Bill, Morrison‐Bogorad, Marcelle, Wagster, Molly V., Phelps, Creighton H., Sperling, Reisa Anne , Rowe, Christopher Cleon , Bennett, David A. , Jack, Clifford R , Stern, Yaakov
Alzheimer's & Dementia | April 22, 2011 | Volume: 7 | Issue: 3 | Pages: 280-292
The pathophysiological process of Alzheimer's disease (AD) is thought to begin many years before the diagnosis of AD dementia. This long “preclinical” phase of AD would provide a critical opportunity for therapeutic intervention; however, we need to further elucidate the link between the pathological cascade of AD and the emergence of clinical symptoms. The National Institute on Aging and the Alzheimer's Association convened an international workgroup to review the biomarker, epidemiological, and neuropsychological evidence, and to develop recommendations to determine the factors which best predict the risk of progression from “normal” cognition to mild cognitive impairment and AD dementia. We propose a conceptual framework and operational research criteria, based on the prevailing scientific evidence to date, to test and refine these models with longitudinal clinical research studies. These recommendations are solely intended for research purposes and do not have any clinical implications at this time. It is hoped that these recommendations will provide a common rubric to advance the study of preclinical AD, and ultimately, aid the field in moving toward earlier intervention at a stage of AD when some disease‐modifying therapies may be most efficacious.