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An, Kai‐Nan

https://orcid.org/0000-0003-4105-9167

Mayo Clinic

Mayo Clinic

Citations 121

The Effect of Radioscapholunate Fusion On Wrist Movement and the Subsequent Effects of Distal Scaphoidectomy and Triquetrectomy
Berkhout, Merel J.-L. , Shaw, Miranda N., Berglund, Lars , An, Kai‐Nan , Berger, Richard A. , Ritt, Marco J.P.F.

Journal of Hand Surgery (European Volume) | April 28, 2010 | Volume: 35 | Issue: 9 | Pages: 740-745

10.1177/1753193410370926 Get It

Radioscapholunate arthrodesis is a salvage procedure indicated for osteoarthritis of the radiocarpal joint involving the lunate facet of the radius. This cadaver study examines changes in wrist motion resulting from radioscapholunate arthrodesis, and the effects of surgical techniques to improve the range of motion. Simulated radioscapholunate arthrodesis, distal scaphoidectomy and triquetrectomy were carried out sequentially on six cadaver forearms and measurements (maximum flexion/extension and radial/ulnar deviation) were taken in the intact situation and after each surgical step using a magnetic tracking device. Radioscapholunate arthrodesis diminishes the amplitudes of movements of the wrist in all directions, but range of motion in the radioscapholunate fused wrist improves after scaphoidectomy and improves further after triquetrectomy (88% of original flexion/extension and 98% of original radial/ulnar deviation). Radioscapholunate arthrodesis causes a significant change in kinematics between the hamate and the triquetrum in flexion/extension.
Effect of Posteroinferior Capsule Tightness on Contact Pressure and Area beneath the Coracoacromial Arch during Pitching Motion
Muraki, Takayuki , Yamamoto, Nobuyuki , Zhao, Kristin D. , Sperling, John W. , Steinmann, Scott P. , Cofield, Robert H. , An, Kai‐Nan , Trentadue, Taylor P

The American Journal of Sports Medicine | December 4, 2009 | Volume: 38 | Issue: 3 | Pages: 600-607

10.1177/0363546509350074 Get It

Background Tightness of the posteroinferior capsule is assumed to be the cause of internal rotation loss in baseball pitchers. Although the relationship between posterior capsule and subacromial impingement has been recognized, this relationship during the baseball-pitching motion is unclear. Hypothesis Contact pressure during baseball-pitching motion increases with posterior capsule tightness. Study Design Controlled laboratory study. Methods Eight fresh-frozen shoulders were used. The peak contact pressure and area on the coracoacromial arch were measured on a custom-designed shoulder experimental device capable of 6 degrees of freedom motion. Simultaneously, the sites of peak pressure on the coracoacromial arch and humerus were observed from various angles. The posteroinferior capsule tightness was simulated by plicating the capsule in the region from 6 to 8 o'clock. The static testing positions correlated to the early cocking, late cocking, acceleration, deceleration, and follow-through phases of the pitching motion. Results The peak contact pressure during the follow-through phase (0.63 ± 0.50 MPa) significantly increased with posteroinferior capsule tightness (1.00 ± 0.65 MPa) (P = .014). Additionally, the contact area on the coracoacromial ligament during the follow-through phase (0.98 ± 0.67 cm2) significantly increased with posteroinferior capsule tightness (1.47 ± 0.91 cm 2) (P < .001). The site of the peak contact pressure did not change between the 2 conditions. Conclusion Our findings demonstrate that posteroinferior capsule tightness leads to higher contact pressure under the subacromial arch and increased contact area, particularly on the coracoacromial ligament during the follow-through phase. Clinical Relevance This tightness may affect risk of injury of the rotator cuff and its surrounding tissues by increasing subacromial contact during pitching.
BIOMECHANICS OF WHEELCHAIR PROPULSION
Lin, Chien-Ju, Lin, Po-Chou, Su, Fong‐Chin , An, Kai‐Nan , Lin, Chien-Ju

Journal of Mechanics in Medicine and Biology | June 26, 2009 | Volume: 09 | Issue: 02 | Pages: 229-242

10.1142/s0219519409002948 Get It

With progress of modern technology, manually-propelled wheelchairs are still of importance for individuals with mobility impairments. The repeated wheelchair propulsion and strenuous daily activities cause high loads and thus injuries on the upper extremity joints. Over the past few years, a considerable number of studies have been made on biomechanical analysis of wheelchair propulsion and wheelchair-related activities. Thorough investigation of biomechanics during wheelchair propulsion enhances comprehension of mechanism of injuries and provides information to improve wheelchair design and fitting. Numerous investigations have been made to demonstrate factors which cause low effectiveness of force application and inefficiency of movements. Emphasis was also placed on developing analytical models to simulate wheelchair propulsion.
Electrogoniometer for the Measurement of Human Elbow Joint Rotation
Chao, Edmund Y.S., An, Kai‐Nan , Askew, Linda J., Morrey, B.F.

Journal of Biomechanical Engineering | June 15, 2009 | Volume: 102 | Issue: 4 | Pages: 301-310

10.1115/1.3138227 Get It

Since the electrogoniometric method has been justified for the measurement of lower extremity joint motion, a similar device is developed for the measurement of elbow joint and forearm rotations. In this design, the axis of forearm rotation coincides with the anatomical axis which eliminates the cross talk existing in the regular triaxial goniometer. Although the axis of abduction-adduction is still offset from the elbow joint, special linkage arrangement was used to obtain equivalent motion. Experimental method was used to validate the accuracy of the device and model simulation was performed to emphasize the importance of accurate placement of the instrument on test subjects. Application of the present apparatus to normal subjects was studied to illustrate the range of elbow motion required in performing normal activities of daily living. This device is currently used in the functional evaluation of patients with elbow and forearm problems.
SYNERGISTIC WRIST DYNAMIC SPLINT FOR FLEXOR TENDON REPAIR
Chou, Pei-Hsi, Chou, You-Li, An, Kai‐Nan , Lin, Gau‐Tyan, Su, Fong‐Chin , Yang, C.S., HUANG, GWO-FENG

Biomedical Engineering: Applications, Basis and Communications | December 16, 2008 | Volume: 13 | Issue: 05 | Pages: 231-241

10.4015/s1016237201000297 Get It

Tendons are frequently injured by direct trauma. Tendon adhesions were a common sequel of tendon repair and are one of the most challenging problems in hand surgery. The concept of “controlled motion” gradually replaced “total immobilization” in the treatment of flexor tendon injuries and today represents a standard of care for all primary repaired flexor tendon injury. Use of controlled motion splints during the early stages of stages of tendon recovery in crease tendon gliding. However, how best to achieve passive motion and the effect of passive motion on tendon gliding have remained controversial subjects. Based on a series of recent experiments, the concept of “dynamic synergistic wrist motion splint” was established and evaluated. It was found that this synergistic wrist motion increases the tendon excursion due to eliminating the laxity and buckling of tendon in the regions between pulleys without introduce excessive amount of tension. The purpose of this study is to design and fabricate a dynamic splint based on this concept and define the nature coordinated motion between the wrist and finger joints due to the passive tension of the muscles in vivo. Parametric analysis will be conducted to achieve an optimum design with the consideration of anatomic constraints. Clinical trial of using such dynamic splint will be evaluated in the future.
MOMENT ARMS OF THE ARM MUSCLES AT THE GLENOHUMERAL JOINT USING THE TENDON EXCURSION METHOD
Itoi, Eiji, Lee, Seok-Beom, Berglund, Lawrence J., Schultz, Fredrick M., Neale, Patricia G., An, Kai‐Nan

Journal of Musculoskeletal Research | September 15, 2008 | Volume: 11 | Issue: 02 | Pages: 45-53

10.1142/s0218957708001973 Get It

Muscle moment arm defines the function of the muscle. To date, moment arms of the arm muscles at the glenohumeral joint using the tendon excursion method have not been reported. As the functions of these muscles at the shoulder joint are controversial, this study was undertaken to determine the moment arms of the long and short heads of the biceps (LHB, SHB), the coracobrachialis, and the long head of the triceps muscles. The moment arms were determined in 10 cadaveric shoulders by measuring the tendon excursion when the arm was rotated by 1 radian (57.3°) in 22 different motions. The LHB was a flexor, horizontal flexor, and abductor. The SHB and coracobrachialis were flexors, horizontal flexors, and adductors. The long head of the triceps was an extensor and adductor. Arm rotation significantly affected the function of the LHB only: it was an internal rotator in flexion and an external rotator in abduction. This study clarifies the individual function of the arm muscles at the glenohumeral joint.
Analysis of Finger PIP Implants
Stone, J.J., Yu, Hongrong, Linscheid, Ronald L., Cooney, William P., An, Kai‐Nan

Advances in Bioengineering | May 16, 2008 | Volume: No volume available | Issue: No issue available | Pages: 289-290

10.1115/imece2003-43307 Get It

Total joint arthroplasty (TJA) is implemented primarily for the relief of pain, and secondarily for achieving better function by increasing the joint’s strength and motion. In order to keep health costs low, it is desirable that the TJA achieves and maintains a long-term and secure fixation of the implanted components. Unfortunately, clinical follow-up shows that the prosthetic finger implant components have long-term complications including bone resorption, wear, loosening, and failure of the implant components. Although the mechanism of complications is not fully understood, it is well known that the wear and failure of prostheses are highly related to the mechanical forces or stresses of implant components. It is therefore desirable that reliable 3-D computational finite element analysis (FEA) models can be developed and used for the stress analysis of implants. In this study, the finger proximal interphalangeal (PIP) prosthetic components were analyzed using a nonlinear finite element method. Implant components under different joint flexion angles as well as different forces were studied. The stress distribution on the contact surface of the implant component was obtained. The developed FEA models can be used to examine the contact situations (contact stress, contact region, and stress distribution), which are critical to the wear and potential failure of the implant components. Based on FEA results, the design of the current finger PIP implants can be improved for optimum performance and a long-term fixation.
Computer-Aided Design, Manufacturing, and Modeling of Polymer Scaffolds for Tissue Engineering
Stone, J.J., Thoreson, Andrew R. , Langner, Kurt L., Norton, Jay M., Stone, D.J. , Wang, Francis W., O’Driscoll, Shawn W. , An, Kai‐Nan , Langner, Kurtis L., Fitzsimmons, James S

Manufacturing Engineering and Materials Handling, Parts A and B | April 3, 2008 | Volume: No volume available | Issue: No issue available | Pages: 169-174

10.1115/imece2005-81621 Get It

A custom computer-controlled rapid prototyping system was designed and developed in this research. This system for bio-manufacturing of polymer scaffolds included 3D motion control components, a nozzle, a pressure controller, and a temperature-controlled reservoir containing a biomaterial. Heating elements built into the reservoir melted the biomaterial. The pressure line attached to the reservoir provided a controllable force that extruded the polymer biomaterial through the nozzle and deposited the polymer biomaterial onto a platform to fabricate scaffolds. A low pressure (830 KPa) system was designed and fabricated to accommodate different temperatures, motion speeds, and viscosities of polymer biomaterials. The reservoir with the nozzle was mounted to servo motor-controlled linear x-y motion devices along with a third servo motor-controlled device that controlled the z-position of the platform. Poly(ε-caprolactone) [PCL] was used to fabricate scaffolds with designed structure that were used in cell and tissue regeneration studies. 3D computer-aided design (CAD) with Pro-Engineer and computational finite element analysis (FEA) programs with MSC_Patran and MSC_Marc were used to model scaffold designs with appropriate architecture and material selection. The CAD models were used in FEA to develop new methods for determining mechanical properties of tissue scaffolds of desired structure and geometry. FEA models were validated by mechanical testing and other published results. Technology developed in this research has potential for the advancement of bio-manufacturing, and design optimization of scaffolds for tissue engineering.
The Addition of Rotator Interval Closure after Arthroscopic Repair of Either Anterior or Posterior Shoulder Instability
Mologne, Timothy S. , Zhao, Kristin D. , Hongo, Michio , Romeo, Anthony A. , An, Kai‐Nan , Provencher, Matthew T. , Trentadue, Taylor P

The American Journal of Sports Medicine | March 4, 2008 | Volume: 36 | Issue: 6 | Pages: 1123-1131

10.1177/0363546508314391 Get It

Background Although the use of rotator interval closure is frequently advocated as a useful supplement to shoulder instability repairs, the addition of a rotator interval closure after arthroscopic instability repair has not been fully investigated. Purpose The objective of this study was to investigate whether a rotator interval closure improves glenohumeral stability in an anterior and posterior instability shoulder model. Study Design Controlled laboratory study. Methods Fourteen fresh-frozen cadaveric shoulder specimens were dissected free of soft tissues, leaving the rotator cuff intact with simulated cuff loading. All specimens were mounted in a custom testing apparatus using infrared sensors to document glenohumeral translation and rotation. The specimens were then tested for stability in the following order: vented/subluxated state, after arthroscopic anterior (Group 1; 7 specimens) or posterior (Group 2; 7 specimens) instability repair with suture anchors, and then after rotator interval closure. For each of the 3 testing conditions, the following were measured: (1) external and internal rotation at neutral, (2) external and internal rotation at 90° of abduction, (3) posterior and anterior translation at neutral rotation (15 N and 25 N), (4) anterior translation at 90° of abduction and external rotation (Group 1; 15 N and 25 N), (5) posterior translation at 90° of flexion and internal rotation (Group 2; 15 N and 25 N), and (6) sulcus testing in neutral (7.5 N). Results Posterior stability was only improved after anchor capsulolabral repair (8.0 to 5.0 mm; P = .017, 25 N), but there was no improvement after rotator interval closure (5.0 to 4.6 mm; P = .453). However, anterior stability was improved after capsulolabral repair (8.6 to 4.0 mm; P = .016, 25 N) and also improved further by rotator interval closure (4.0 to 2.4 mm; P = .007). The mean loss of external rotation was significantly increased by the addition of the rotator interval closure in both neutral and abducted glenohumeral positions, with a mean external rotation loss of 28° in neutral ( P = .013). The addition of a rotator interval closure did not improve sulcus stability ( P = .4). Conclusion The addition of an arthroscopic rotator interval closure after posterior capsulolabral repair did not improve posterior stability; however, anterior stability was improved further after a rotator interval closure. Inferior stability was not improved. Arthroscopic rotator interval closure significantly decreased external rotation at both neutral and abducted arm positions. Clinical Relevance Arthroscopic closure may be beneficial in certain cases of anterior shoulder instability; however, posterior instability was not improved. Predictable losses of external rotation after rotator interval closure are of concern.
Importance of Soft Tissue Integrity on Biomechanical Studies of the Patella After TKA
Luo, Zong-Ping , Hsu, Horng-Chaung, Rand, J.A. , An, Kai‐Nan

Journal of Biomechanical Engineering | February 21, 2008 | Volume: 118 | Issue: 1 | Pages: 130-132

10.1115/1.2795938 Get It

This study evaluated the effects of soft tissue integrity on patellar tracking and patellofemoral joint force after total knee arthroplasty. The results indicate that partial dissection of the soft tissue integrity in the in vitro biomechanical studies of the patellofemoral joint can alter patellar tracking and joint force significantly, leading to improper conclusions.