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Oncolytic wild-type reovirus infection in brain tumors following intravenous administration in patients.
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Journal of Clinical Oncology | January 3, 2019 | Volume: 32 | Issue: 15_suppl | Pages: 3104-3104
Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade
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Science Translational Medicine | January 3, 2018 | Volume: 10 | Issue: 422 | Pages: No page available
Intravenous infusion of oncolytic reovirus in patients leads to infection of brain tumors, infiltration by cytotoxic T cells, and up-regulation of PD-L1.