Citations 2
Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade
Samson, Adel , Scott, Karen J. , Taggart, David J. , Wilson, Erica , Nuovo, Gerard J. , Thomson, Simon , Mathew, Ryan , Fuller, Martin, Kottke, Timothy, Thompson, Jill , Ilett, Elizabeth J. , Cockle, Julia , Hille, Philip van, Sivakumar, Gnanamurthy, Polson, Euan S. , Turnbull, Samantha , Appleton, Elizabeth , Migneco, G , Rose, Ailsa , Coffey, Matthew, Beirne, Deborah , Collinson, Fiona , Ralph, Christy , Anthoney, Alan , Twelves, Christopher , Furness, Andrew J.S. , Quezada, Sergio A. , Wurdak, Heiko , Errington‐Mais, Fiona , Pandha, Hardev , Harrington, Kevin J. , Selby, Peter J. , Vile, Richard G. , Griffin, Stephen , Stead, Lucy F. , Short, Susan , Melcher, Alan , Taggart, David , Wilson, Erica , Nuovo, Gerard J , Thomson, Simon , Mathew, Ryan K , Kottke, Timothy J, Thompson, Jill M, Ilett, Elizabeth J , Cockle, Julia V , Turnbull, Samantha J , Rose, Ailsa S , Beirne, Deborah A , Ralph, Christy , Alan Anthoney, D , Quezada, Sergio A , Wurdak, Heiko , Errington-Mais, Fiona , Selby, Peter J , Griffin, Stephen , Stead, Lucy F , Short, Susan C , Melcher, Alan A , Harrington, Kevin , West, Emma J. , Corns, Robert A. , Appleton, Elizabeth
Science Translational Medicine | January 3, 2018 | Volume: 10 | Issue: 422 | Pages: No page available
Intravenous infusion of oncolytic reovirus in patients leads to infection of brain tumors, infiltration by cytotoxic T cells, and up-regulation of PD-L1.
Cell Carriage, Delivery, and Selective Replication of an Oncolytic Virus in Tumor in Patients
Adair, Robert A. , Roulstone, Victoria , Scott, Karen J. , Morgan, Ruth, Nuovo, Gerard J., Fuller, Martin, Beirne, Deborah , Jennings, Victoria A. , Rose, Ailsa , Fraser, Sheila , Dave, Rajiv , Anthoney, David Alan, Merrick, Alison, Prestwich, Robin, Aldouri, Amer, Donnelly, Oliver , Pandha, Hardev , Selby, Peter J. , Vile, Richard G. , Toogood, Giles J. , Harrington, Kevin J. , Melcher, Alan , West, Emma J. , Kyula, Joan , Coffey, Matt C. , Melcher, Alan A , Harrington, Kevin , Dave, Rajiv V
Science Translational Medicine | June 13, 2012 | Volume: 4 | Issue: 138 | Pages: No page available
Oncolytic reovirus is carried by cells to tumors and protected from neutralizing antibodies in the circulation.