Morales-Nebreda, Luisa C
Mayo Clinic
Department of Medicine, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States.
Citations 2
The Sixth Annual Symposium of the Midwest Aging Consortium
Sturmlechner, Ines , Ashiqueali, Sarah , Martini, Hélène , Valdivieso, Karla , Franco, Ana Catarina , Guthikonda, Prashanth Kumar, Dosch, Andrew J. , Prieto, Luis I. , Asmussen, Niels C. , Latham, Amanda S. , Redden, James T, Leitschuh, Ethan A , Mashek, Douglas G. , Rodriguez-Lopez, Jhonny , Bernlohr, David , Knopf, Bailey A. , Lamming, Dudley W. , Johnston, Matthew J, Brown-Borg, Holly M., Tye, Spencer A, Rhoads, Timothy W. , Childs, Bennett G. , Li, Xinna, Jang, In Hwa, Camell, Christina D. , Miller, Zachary, Phatnani, Hemali , Haak, Andrew J. , Vanegas-Avendaño, Natalia, Akula, Ramya N, Limkar, Ajinkya R. , Leiser, Scott F, Correia, Jacinta , Bai, Hua, Olszewski, Szczepan, Seldeen, Kenneth L. , Budinger, G R Scott, Morales-Nebreda, Luisa C, Winter, Deborah R. , Spitzer, Shelly K McCrady, Rojas, Mauricio , Schafer, Marissa , Ashiqueali, Sarah A , Guthikonda, Prashanth, Rodriguez-Lopez, Jhonny , Monroe, T Blake , Bernlohr, David A , Lamming, Dudley W , Brown-Borg, Holly M , Rhoads, Timothy W , Gate, David M , Baker, Darren J , Li, Xinna , Miller, Zachary , Phatnani, Hemali , Konopka, Adam R , Limkar, Ajinkya R , Correia, Jacinta , Bai, Hua , Olszewski, Szczepan , Seldeen, Kenneth L , Morales-Nebreda, Luisa C , Winter, Deborah R , McCrady-Spitzer, Shelly K , Anderson, Rozalyn M , LeBrasseur, Nathan K , Schafer, Marissa J , Sturmlechner, Ines , Redden, James T., Passos, João F. , Robbins, Paul D. , Brown‐Borg, Holly M. , Tye, Spencer, Baker, Darren J. , Jang, In Hwa , Konopka, Adam R. , Ricke, William A. , Leiser, Scott F. , Morales‐Nebreda, Luisa , Anderson, Rozalyn M. , Mihaylova, Maria M. , Mora, Ana Lucia , LeBrasseur, Nathan K.
The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences | December 23, 2025 | Volume: 81 | Issue: 3 | Pages: No page available
Abstract Geroscience research benefits from interdisciplinary approaches, team science, and collaborations, which collectively facilitate the discovery of aging mechanisms and their translation into tangible, clinical interventions. Since its inception in 2019, the Midwest Aging Consortium (MAC) has provided an engaging platform for aging researchers in the United States’ Midwest to connect, collaborate, and exchange ideas. The Sixth Annual Research Symposium of the MAC held at the Mayo Clinic in Rochester, Minnesota, in April 2025 highlighted the continued impact of the MAC in bringing together aging researchers, including many trainees and early career investigators, into a collaborative environment. This record-setting event featured interdisciplinary research on key aging mechanisms, including lipid metabolism, mitochondrial dysfunction, stress response, cellular senescence, and immune adaptations across organ systems. New therapeutic concepts and clinical trial approaches were presented. Cutting-edge methodologies including single-cell and spatial transcriptomics, metabolomics, and organoid cultures, to dissect aging process in tissue-specific and systemic contexts also were presented. Overall, the MAC symposium underscored the translational potential of geroscience and reinforced the MAC’s mission to accelerate aging research through regional collaborations and innovation.
The Third Annual Symposium of the Midwest Aging Consortium
Keller, Andrea , Eliazer, Susan , Hansen, Malene , Konopka, Adam R. , Morales‐Nebreda, Luisa , Najt, Charles P. , Prahlad, Veena , Victorelli, Stella , Yuan, Rong , Rhoads, Timothy W. , Konopka, Adam R , Vorland, Colby J , Rhoads, Timothy W , Morales-Nebreda, Luisa C , Bai, Hua , Budinger, G. R. Scott , Mihaylova, Maria M.
The Journals of Gerontology: Series A | October 7, 2023 | Volume: 79 | Issue: 2 | Pages: No page available
Abstract The geroscience hypothesis suggests that addressing the fundamental mechanisms driving aging biology will prevent or mitigate the onset of multiple chronic diseases, for which the largest risk factor is advanced age. Research that investigates the root causes of aging is therefore of critical importance given the rising healthcare burden attributable to age-related diseases. The third annual Midwest Aging Consortium symposium was convened as a showcase of such research performed by investigators from institutions across the Midwestern United States. This report summarizes the work presented during a virtual conference across topics in aging biology, including immune function in the lung—particularly timely given the Corona Virus Immune Disease-2019 pandemic—along with the role of metabolism and nutrient-regulated pathways in cellular function with age, the influence of senescence on stem cell function and inflammation, and our evolving understanding of the mechanisms underlying observation of sex dimorphism in aging-related outcomes. The symposium focused on early-stage and emerging investigators, while including keynote presentations from leaders in the biology of aging field, highlighting the diversity and strength of aging research in the Midwest.