Background Patients with substance use disorder (SUD) have high rates of hospitalization, readmission, and prolonged lengths of stay. Objectives To conduct a systematic review and meta-analysis of the impact of addiction consult services in the inpatient setting for patients with SUD. Methods Five databases were systematically searched from their earliest available records through January 2025. Two authors independently screened articles, extracted data, and assessed the quality of each study with the Newcastle-Ottawa Scale for observational studies and the Cochrane risk-of-bias tool for randomized clinical trials. Pooled odds ratios (ORs) with 95% CIs were calculated for dichotomous outcomes, and mean differences were calculated for continuous outcomes. Results The search retrieved 20 studies that met inclusion criteria. The intervention for all studies was an addiction medicine consult, but the definition of this consult varied. The meta-analysis did not detect statistically significant differences in hospital length of stay, hospital readmission, or emergency department visits at 1 year among patients who received the consult compared with those who did not; however, many of these outcomes were likely underpowered. However, addiction medicine consults significantly improved the odds of inpatient initiation of medication for SUD (OR, 7.30; 95% CI, 3.30-16.13; P <.001) and postdischarge SUD treatment linkage and adherence (OR, 3.31; 95% CI, 2.06-5.32; P <.001). Conclusion Inpatient addiction consult services are associated with increased inpatient initiation of medication for SUD treatment and postdischarge treatment linkage and adherence. No clear association was identified between the consult and readmissions, emergency department utilization, or length of stay.
Promoting longitudinal healthcare access for immigrants: Retrospective analysis of a free clinic serving Arizona refugees
Abstract Background: Refugee, immigrant, and asylee populations face significant barriers to healthcare access, including linguistic, cultural, socioeconomic, and institutional challenges. The Refugee Education and Clinic Team (REACT) is a student-run free clinic in Maricopa County, Arizona, providing subacute care and referrals to federally qualified health centers (FQHCs). This study evaluates patient demographics, clinical needs, social determinants of health (SDH), and follow-up outcomes to identify barriers to long-term care integration. Methods: A retrospective chart review of all REACT patients (2022–2024) was conducted using electronic health records. Data on demographics, SDH, chief complaints, prescriptions, referrals, and follow-up outcomes were analyzed using descriptive statistics and logistic regression. Results: The cohort (n=95) was predominantly uninsured (63%) and faced significant social barriers, including food insecurity (30.5%), employment challenges (30.5%), and language barriers (28.4%). Musculoskeletal pain and general health check-ups were the most common concerns. Older patients had higher-than-expected rates of possible hypertension. Nearly 90% received primary care provider (PCP) referrals, yet follow-up rates remained low, with only 42% attending or planning to still attend the referred visit after their initial clinic visit with us. Successful phone outreach was a significant predictor (OR: 0.5, 95% CI: 0.31-0.77) of PCP visit attendance by multivariate logistic regression. Conclusion: REACT serves a unique population with distinct barriers to care. While the clinic facilitates healthcare entry, limited follow-up adherence highlights the need for enhanced outreach, geographically optimized referrals, and integrated allied health services to improve care continuity.
Resident and hospitalist perspectives on the “great teaching case”: Correlation with actual patient assignment decisions
Objective. To report an unusual cause of coma in an adult.Design. Case report.Setting. University teaching hospital.Patient. A previously healthy 53-year-old man initially presented with altered mental status and progressed to coma. He was found to be substantially hyperammonemic and did not improve with lactulose therapy and continuous venovenous hemodialysis.Results. Biochemical testing revealed previously undiagnosed ornithine transcarbamylase deficiency, and the patient responded to arginine, sodium phenylacetate, and sodium benzoate.Conclusion. Even in adult patients with no known history, inborn errors of metabolism must be considered in the differential diagnosis of unexplained coma. Defects of the urea cycle can present with an unprovoked hyperammonemic coma.