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Sayed, Rana S.

Mayo Clinic

Cairo University

Citations 1

Nutritional interventions in cardiac rehabilitation: current evidence, evidence gaps, and future directions—a scoping review
Elalfy, Aya, Abdelnabi, Mahmoud , Mohamed, Ahmed Elmorsy, VanDolah, Hunter , Sayed, Rana S., Kholeif, Zeyad, Rashwan, Rana, Ibrahim, Ramzi , Perone, Francesco , Arsanjani, R A, S Sayed, Rana , J Thomas, Randal, Ayoub, Chadi , VanDolah, Hunter , Perone, Francesco , Kholeif, Zeyad , Rashwan, Rana , Ibrahim, Ramzi , Thomas, Randal J. , Arsanjani, Reza

European Journal of Preventive Cardiology | July 18, 2026 | Volume: No volume available | Issue: No issue available | Pages: No page available

10.1093/eurjpc/zwag375 Get It

Abstract Aims Nutritional counselling is a core component of cardiac rehabilitation (CR), yet the evidence base for specific dietary interventions within CR remains fragmented. This scoping review aimed to map the range of nutritional interventions evaluated in adult CR programmes, characterize their reported outcomes, and identify key gaps in current evidence and practice. Methods and results Following the Arksey and O’Malley framework and reporting according to PRISMA-ScR, a systematic search of PubMed, Embase, Web of Science, and Cochrane Library was conducted from inception to June 2026. Eligible studies included randomized controlled trials, non-randomized trials, and observational studies evaluating an explicitly described nutritional intervention within a structured CR programme in adults with established cardiovascular disease. Of 2765 identified records, 35 studies met eligibility criteria. Interventions spanned Mediterranean and heart-healthy dietary patterns, calorie-restriction and weight-loss programmes, comprehensive lifestyle interventions, structured nutrition education and counselling, supplementation, functional foods, and individualized diet prescriptions. Across categories, improvements in body weight, central adiposity, and adherence to cardioprotective dietary recommendations were commonly reported, particularly when nutrition was delivered with repeated contact and individualized support. Effects on lipid profiles, inflammatory markers, blood pressure, functional capacity, and clinical outcomes were more variable. Conclusion Nutritional interventions within CR were most consistently associated with improvements in intermediate behavioural, anthropometric, and cardiometabolic outcomes, particularly when structured and reinforced over time. However, heterogeneity in study design, intervention delivery, comparator groups, outcome reporting, and follow-up duration precludes definitive conclusions about comparative efficacy, optimal intervention format, or the magnitude of benefit. Greater standardization, longer follow-up, and further evaluation of personalized nutritional strategies are needed to strengthen the nutritional component of CR.