Citations 3
Pericardial Effusion and Bruton Tyrosine Kinase Inhibitors in B-Cell Malignant Disease
Zanco, Julia , Ibrahim, Ramzi, Pham, Hoang Nhat, Farina, Juan M., Narayanasamy, Hema, Tamarappoo, Balaji , Herrmann, Joerg, Ayoub, Chadi, Arsanjani, Reza, Larsen, Carolyn M , Ibrahim, Ramzi , Pham, Hoang Nhat , Farina, Juan M., Larsen, Carolyn , Herrmann, Joerg , Arsanjani, Reza
JAMA Oncology | February 19, 2026 | Volume: 12 | Issue: 4 | Pages: 419
This cohort study examines the association of bruton tyrosine kinase inhibitor therapy in B-cell malignant disease with increased risk of pericardial effusion and cardiovascular outcomes.
Prognostic Significance of Prolonged QTc Interval in Patients on Dialysis: A Retrospective Cohort Study
Pham, Hoang Nhat, Ibrahim, R, Giauque, Nathan A., Mahmoud, Ahmed K., Dreher, Luke, Scott, Luis R., Ayoub, Chadi, Arsanjani, Reza, LeMond, Lisa , Singh, Amitoj, Sorajja, Dan , Ayoub, Chadi , Ayoub, Chadi , Pham, Hoang Nhat , Giauque, Nathan Anthony, Mahmoud, Ahmed K , Dreher, Luke , Scott, Luis R. , Arsanjani, Reza , Singh, Amitoj
Journal of Arrhythmia | February 19, 2026 | Volume: 42 | Issue: 1 | Pages: No page available
ABSTRACT Background Prolonged QT interval is common in end‐stage renal disease (ESRD) on dialysis, but its long‐term cardiovascular (CV) implications remain unclear. Methods Using TriNetX network (2010–2024), we identified adults with ESRD on dialysis and categorized them by QTc status. After 1:1 propensity score matching ( n = 3428/group), outcomes (hazard ratio [HR]) were assessed using Cox regression. Results Prolonged QTc (> 500 ms) was associated with higher risk of all‐cause mortality (HR 1.67; p < 0.001), MACEs (HR 1.40; p < 0.001), cardiac arrest (HR 1.75; p < 0.001), sustained ventricular arrhythmia (HR 1.66; p < 0.001), new‐onset atrial fibrillation (HR 1.12; p = 0.01), and acute myocardial infarction (HR 2.19; p < 0.001). Conclusions In ESRD patients on dialysis, prolonged QT interval was independently associated with adverse CV outcomes and mortality.
Percutaneous Left Atrial Appendage Occlusion for Atrial Fibrillation in Cardiac Amyloidosis
Almakadma, Abdul Hakim , Ibrahim, Ramzi, Pham, Hoang Nhat, Habib, Eiad, Mahmoud, Ahmed K., Awad, Kamal, Bhakta, Mayurkumar D. , Yang, Eric H., Masry, Hicham Z. El, Ayoub, Chadi, Arsanjani, Reza, Ayoub, Chadi , Masry, Hicham El , Awad, Kamal , El Masry, Hicham , Ayoub, Chadi , Ibrahim, Ramzi , Pham, Hoang Nhat , Habib, Eiad , Mahmoud, Ahmed K , Awad, Kamal , Yang, Eric H. , Arsanjani, Reza
Journal of Arrhythmia | January 27, 2026 | Volume: 42 | Issue: 1 | Pages: No page available
ABSTRACT Background Cardiac amyloidosis (CA) is frequently complicated by atrial fibrillation (AF), yet outcomes after left atrial appendage occlusion (LAAO) in this population remain poorly defined. Methods We conducted a retrospective TriNetX study of adults with AF undergoing LAAO, comparing patients with and without CA after 1:1 propensity matching. Outcomes were assessed using Kaplan–Meier analyses and Cox regression. Results Among 532 matched pairs, mortality and major adverse cardiovascular events were similar between groups, whereas major bleeding was higher in CA (HR 1.90). Conclusions LAAO yields comparable ischemic outcomes in CA, though bleeding risk is increased.