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Hoffer, Alexander J

https://orcid.org/0000-0003-2505-4040

Mayo Clinic

Mayo Clinic in Arizona

Citations 10

Adding a Lateral Extra‐articular Tenodesis to Quadriceps Autograft Anterior Cruciate Ligament Reconstruction Reduces Risk of Graft Failure
Renfree, Sean P. , Brinkman, Joseph C. , Tummala, Sailesh V. , Economopoulos, Kostas J. , Hoffer, Alexander J , Economopoulos, Kostas J , Renfree, Sean , Tummala, Sailesh V

Arthroscopy | July 1, 2026 | Volume: No volume available | Issue: No issue available | Pages: No page available

10.1002/arj.70398 Get It

Purpose The purpose of this study was to compare graft failure and clinical outcomes following primary anterior cruciate ligament reconstruction (ACLR) using quadriceps tendon autograft (QA), with or without a modified Lemaire lateral extra‐articular tenodesis (LET). Methods Patients with ACL deficiency who underwent primary QA ACLR with or without LET and completed at least 2‐year follow‐up were included. Patients with a Beighton score ≥4, a preoperative pivot shift grade ≥2, or an intention to return to cutting and pivoting sports were offered LET. The primary outcome variable assessed was graft failure as defined by graft rupture or grade ≥2 pivot shift at any point postoperatively. Secondary outcomes included return to sport clearance rates, the International Knee Documentation Committee and Lysholm scores and postoperative complications. Results There were 122 undergoing QA ACLR with LET (QA + LET group) and 152 undergoing isolated QA ACLR (QA group). The QA + LET group had a significantly lower failure rate of 14.8% versus 29.6% in the QA group ( P = .02). In addition, the QA + LET group had a lower residual pivot shift rate compared with the QA group (11.3% vs. 26.3% respectively; P = .01). There was no difference in graft retear rates between the 2 groups ( P = .37). The QA + LET returned to sport significantly faster at 8.8 months compared with 9.7 months in the QA group ( P = .038). Conclusions The addition of LET to QA ACLR was associated with a significantly lower overall graft failure rate and lower percentage of patients with residual pivot shifts after ACLR compared with QA alone at 2‐year follow up. However, there was no difference between the 2 groups with regard to graft retear rates. The addition of an LET to QA ACLR also allowed athletes to return to sports faster compared with QA alone. Level of Evidence Level III, retrospective comparative study.
Outcomes of Multiply Revised ACL Reconstruction with Quadriceps Tendon Autograft plus Lateral Extra-articular Tenodesis in Competitive Athletes
Tummala, Sailesh V. , Brinkman, Joseph C. , Parmar, Romir , Haglin, Jack M. , Hoffer, Alexander J , Economopoulos, Kostas J. , Tummala, Sailesh V

Orthopaedic Journal of Sports Medicine | May 16, 2025 | Volume: 13 | Issue: 5 | Pages: No page available

10.1177/23259671251337478 Get It

Background: The number of multiply revised anterior cruciate ligament reconstructions (rrACLRs) performed each year continues to increase. The most reliable graft type and surgical technique in the young, active patient remains to be determined. Purpose: To determine the outcomes of rrACLR using quadriceps tendon (QT) autograft with lateral extra-articular tenodesis (LET). Study Design: Case series; Level of evidence, 4. Methods: A retrospective review was performed of all competitive athletes undergoing rrACLR with QT autograft and LET at a single institution with a minimum follow-up of 2 years. Patient demographics, physical examination, and radiological findings, and previous surgical details were documented. Patient outcomes were noted, including the International Knee Documentation Committee (IKDC) and Lysholm scores, ability to return to sport and return at the same level of play, retear rate, and other complications. Results: A total of 19 rrACLRs were performed and met inclusion criteria in the 10-year study period. All participants were high school, collegiate, or professional athletes with a mean age of 22 years, and 63.2% were female. The mean follow-up was 42.3 months, and IKDC scores increased from 51.6 preoperatively to 74.7 at the final follow-up ( P < .001). Likewise, the Lysholm score increased significantly from a preoperative value of 53.6 to 76.8 at the final follow-up ( P < .001). Return to play was possible in 52.6% of the patients at a mean of 11.5 months, with 31.6% returning to the same or higher level of play. One (5.3%) patient experienced a recurrent ACL tear, and 2 (10.5%) experienced a contralateral tear. Arthrofibrosis requiring surgical intervention occurred in 26.3% of the athletes. Conclusion: Short- to midterm results demonstrated that competitive athletes who received an rrACLR using a QT autograft with LET had statistically significant improvements in both IKDC and Lysholm scores, with more than half of patients being able to return to sport and nearly a third returning at the same or higher level of play. In the setting of a third ACL reconstruction, quadriceps tendon autograft with LET is a reasonable option even in high-risk patients.
The Role of Isolated Lateral Extra-Articular Tenodesis in Managing Residual Pivot Shift After Primary Anterior Cruciate Ligament Reconstruction and a New Medial Meniscal Tear
Brinkman, Joseph C. , Economopoulos, Sofia C., Hoffer, Alexander J , Economopoulos, Kostas J. , Tummala, Sailesh V , Tummala, Sailesh V.

Orthopaedic Journal of Sports Medicine | February 6, 2025 | Volume: 13 | Issue: 2 | Pages: No page available

10.1177/23259671241308570 Get It

Background: Persistent mildly abnormal knee kinematics after anterior cruciate ligament (ACL) reconstruction (ACLR) is an ongoing clinical problem. Purpose: To compare the clinical outcomes of revision ACLR (rACLR), rACLR and lateral extra-articular tenodesis (LET), or isolated LET in patients with a grade ≥2 pivot shift after ACLR with an intact or partially torn graft and a new, symptomatic medial meniscal tear. Study Design: Cohort study; Level of evidence, 3. Methods: A retrospective review of all patients with a new, symptomatic medial meniscal tear diagnosed after a primary ACLR was performed. Patients were included if they demonstrated a grade ≥2 pivot shift on physical examination with an intact or partially torn ACL graft. Exclusion criteria included complete graft rupture. The senior author’s management evolved in a practice change design from rACLR to rACLR with LET, to isolated LET over the study period. The primary outcomes were the International Knee Documentation Committee (IKDC), Lysholm, and Tegner patient-reported outcomes (PROs) at 2 years postoperatively. Results: A total of 47 patients, with 16 in the rACLR group, 12 in the rACLR and LET group, and 19 in the isolated LET group were included. Baseline characteristics between groups were similar. At 2 years, the rACLR group IKDC score was 86.1 ± 6.6 and was lower than the rACLR and LET group (91.9 ± 4.4; P = .009; 95% CI, –10.4 to −1.2) and the isolated LET group scores (91.7 ± 3.0; P = .004; 95% CI, –9.7 to −1.6). The Lysholm score was lower in the rACLR group (85.8 ± 6.3) when compared with the rACLR and LET group (91.8 ± 4.6; P = .03; 95% CI, –11.8 to −0.39). There was no difference in any Tegner scores at 2 years ( P = .09). Conclusion: In patients with grade ≥2 pivot shift after an ACLR with an intact or partially torn graft and a new, symptomatic medial meniscal tear, the addition of an LET with or without rACLR led to improved PROs compared with an isolated rACLR. An isolated LET in this patient population should be considered an acceptable treatment option.
Anterior Cruciate Ligament Reconstruction Using Hamstring Autograft Plus Lateral Extra‐articular Tenodesis and All‐Soft Tissue Quadriceps Alone Have Lower Retear Rate and Pivot‐Shift Grade but Similar Outcome to Hamstring Autograft Alone in High‐Risk Patie
Brinkman, Joseph C. , McQuivey, Kade S. , Braithwaite, Collin , Paul, Benjamin C. , Verhey, Jens T. , Haglin, Jack M. , Hoffer, Alexander J , Economopoulos, Sofia C., Economopoulos, Kostas J. , Braithwaite, Collin L , Economopoulos, Kostas J

Arthroscopy | January 21, 2025 | Volume: 41 | Issue: 8 | Pages: 2988-2995

10.1016/j.arthro.2025.01.011 Get It

Purpose To compare the surgical outcomes of anterior cruciate ligament (ACL) reconstruction using hamstring autograft (HA) plus lateral extra‐articular tenodesis (LET), isolated all‐soft tissue quadriceps autograft (QA), and isolated HA. Methods A retrospective review was performed comparing high‐risk patients undergoing ACL reconstruction with isolated HA, isolated QA, or HA + LET from August 2013 to January 2023. High‐risk patients, as determined by high‐grade pivot shift or generalized ligament laxity, with at least a 2‐year follow‐up, were included. Lysholm and International Knee Documentation Committee scores were compared at 3, 6, 12, and 24 months postoperatively. Retear rate, postoperative pivot‐shift grade, return to sport, and complications were recorded. Results In total, 159 patients (56 HA, 47 HA + LET, and 56 QA) were included. At 6 months postoperatively, the HA International Knee Documentation Committee score was significantly lower than that of the HA + LET and QA groups ( P < .0001). Similarly, the Lysholm score was significantly lower in the HA cohort at 6 months, 1 year, and 2 years postoperatively ( P < .0001‐.02). There was no difference in the rate of achieving the minimally important clinical difference between the cohorts for either of these outcome scores. The retear rate was significantly higher in the HA group (17.9%) compared to the HA + LET (4.3%) and QA (1.8%) cohorts ( P = .01). The rate of postoperative pivot shift of grade 2 or more was also higher in the isolated HA group ( P = .04). Conclusions The use of an all‐soft tissue QA or HA + LET for ACL reconstruction resulted in a lower retear rate and postoperative pivot‐shift grade compared to an isolated HA graft in high‐risk patients at 2 years postoperatively. There was no difference in the rate of achieving the minimal clinically important difference between the cohorts. The QA and HA + LET reconstruction options may improve stability and decrease the failure rate compared with HA reconstruction alone. Level of Evidence Level III, retrospective cohort study.
Pediatric Concussion Injuries in Soccer: Emergency Department Trends in the United States From 2012 to 2023
Sullivan, Georgia , Lin, Eugenia , Richardson, Meghan, Sullivan, Georgia R, Hoffer, Alexander, Hoffer, Alexander J , Richardson, Meghan, Chhabra, Anikar

Orthopaedic Journal of Sports Medicine | December 3, 2024 | Volume: 12 | Issue: 12 | Pages: No page available

10.1177/23259671241303180 Get It

Background: Because of growing concerns regarding repeated head trauma, in 2016, the United States Soccer Federation (USSF) banned headers for athletes aged ≤10 years and limited athletes aged 11 to 13 years to practicing headers for 30 minutes per week. Purpose: To assess whether the USSF header policy was associated with fewer soccer-related concussions after the 2015 season. Study Design: Descriptive epidemiology study. Methods: A retrospective cohort from the National Electronic Injury Surveillance System database was assessed. Age, sex, and injury type were extracted for all soccer-related emergency department visits between January 1, 2012, and December 31, 2023. Univariate and multiple regression analyses were used to assess concussions as a percentage of all soccer-related injuries based on sex, age group (6-9, 10-13, and 14-17 years), and year. The following time frames were assessed: 2012-2015, 2016-2019, and 2020-2023. Results: The proportion of concussions decreased from 8.2% of all soccer-related injuries in 2012-2015 to 6.1% in 2020-2023 ( P < .01). The relative risk reduction for soccer-related concussions presenting to an emergency department in 2020-2023 compared with 2012-2015 was 25.6%. Overall, the proportion of concussions among 10- to 13-year-old and 14- to 17-year-old players was higher than for 6- to 9-year-old players (6.6% and 8.9% vs 4.9%, respectively; P < .01). Despite having a lower frequency of soccer-related injuries overall, female players had a greater proportion of concussions than male players (9.6% vs 6.2% of all soccer-related injuries; P < .01). In the multiple regression analysis, injuries that occurred in 2020-2023 were associated with lower odds of concussion compared with 2012-2015 (odds ratio [OR], 0.75 [95% CI, 0.69-0.81]). Compared with 6- to 9-year-old and male players, the 10- to 13-year-old (OR, 1.30 [95% CI, 1.16-1.45]), 14- to 17-year-old (OR, 1.79 [95% CI, 1.61-1.99]), and female players (OR, 1.53 [95% CI, 1.43-1.63]) were associated with higher odds of concussion. Conclusion: A 25.6% reduction in the relative risk of presenting to the emergency department with a soccer-related concussion was found when comparing 2020-2023 (after USSF header policy implementation) with 2012-2015 (before policy implementation). The USSF youth soccer header policy may improve player safety by reducing head impacts in the pediatric population.
Arthroscopic Congruent‐Arc Distal Tibial Allograft Bone Augmentation With Cerclage Fixation for Anterior Shoulder Instability With Bone Loss
Hoffer, Alexander J , Lai, Cara , Smith, Casandra , Tokish, John M., Lai, Cara H , Tummala, Sailesh V , Tummala, Sailesh V.

Arthroscopy Techniques | November 29, 2024 | Volume: 14 | Issue: 4 | Pages: No page available

10.1016/j.eats.2024.103344 Get It

Abstract Glenoid bone loss is a common sequela of recurrent anterior shoulder instability. When treated surgically, a bone augmentation procedure is more likely to provide a good outcome with a lower risk of recurrent instability compared with a soft‐tissue repair alone. There are several bone augmentation options to address glenoid bone loss, including coracoid transfer, iliac crest autograft, and distal tibial allograft (DTA). Both open and arthroscopic DTA techniques have been described using the lateral one‐third of the distal tibia oriented with the anterior aspect placed superiorly on the anterior glenoid. This graft orientation places its concavity in the superior‐to‐inferior direction. It may be preferred to have this concavity maximized toward the anterior direction so that it can further resist anterior displacement. The posterior one‐third of the distal tibia may provide a more optimal arc of resistance. However, no previous technique has used the posterior one‐third of the distal tibia to reconstruct the “half‐pipe” concavity of the anterior glenoid. We describe an all‐arthroscopic technique for a posterior third DTA oriented with the posterior tibial edge placed anteriorly on the glenoid, termed the “congruent‐arc DTA,” to address anterior shoulder instability with bone loss. Technique Video video See video under supplementary data.
Long‐Term Preoperative Nonsteroidal Anti‐inflammatory Drug Use Does Not Impact Revision Rate After Repair of Rotator Cuff, Achilles, Distal Biceps, or Quadriceps Tendon
Parmar, Romir , Tummala, Sailesh V. , Holle, Alejandro M. , Iturregui, Jose M. , Hoffer, Alexander J , Tokish, John M. , Holle, Alejandro, Iturregui, Jose, Holle, Alejandro , Tummala, Sailesh V

Arthroscopy, Sports Medicine, and Rehabilitation | October 28, 2024 | Volume: 7 | Issue: 2 | Pages: No page available

10.1016/j.asmr.2024.101034 Get It

Purpose To determine whether long‐term preoperative nonsteroidal anti‐inflammatory drug (NSAID) use affected the revision rates after primary tendon repair for the following common sports medicine surgical procedures: rotator cuff repair (RCR), Achilles tendon repair (ATR), distal biceps repair (DBR), or quadriceps tendon repair (QTR). Methods A retrospective comparative study using a national insurance database was performed. Patients who underwent major tendon repair, including RCR, ATR, DBR, or QTR, with at least 2‐year follow‐up were identified. Those who had a diagnosis of long‐term NSAID use prior to the index operation were identified and matched 1:4 to controls without NSAID use based on age, sex, specific tendon repaired, and Elixhauser Comorbidity Index. The revision repair rates of the 2 groups were compared. Results A total of 36,068 patients underwent major tendon repair. Of these, 7,246 (20%) met the long‐term NSAID use criteria prior to tendon repair (NSAID users). After RCR, 3.2% of NSAID users (n = 190) and 2.6% of controls (n = 617) underwent revision surgery within 2 years (odds ratio [OR], 1.15; 95% confidence interval [CI], 0.97‐1.36; P = .10). After ATR, NSAID users had a revision rate of 3.9% (n = 24) versus 2.5% (n = 62) in the control cohort (OR, 1.47; 95% CI, 0.89‐2.38; P = .12). After DBR, both NSAID users and controls had fewer than 11 revision cases (OR, 1.54; 95% CI, 0.49‐4.16; P = .42). After QTR, the revision rate was 5.9% (n = 30) for NSAID users compared with 4.8% (n = 95) for the control group (OR, 1.22; 95% CI, 0.77‐1.86; P = .38). None of the observed differences in revision rates between NSAID users and controls were significant. Conclusions Patients with a diagnosis of and coding for long‐term preoperative NSAID use do not have greater revision rates within 2 years of primary tendon repair than patients without this diagnosis. Level of Evidence Level III, retrospective case‐control study.
Slope‐Reducing Tibial Plateau‐Leveling Osteotomy
Ollivier, Matthieu , Hoffer, Alexander J , Onishi, Shintaro , Brilhault, J. , Frey-Ollivier, Solenne, Godshaw, Brian , Kley, Kristian

Arthroscopy Techniques | September 23, 2024 | Volume: 14 | Issue: 3 | Pages: No page available

10.1016/j.eats.2024.103264 Get It

Abstract Increased posterior tibial slope (PTS) is a risk factor for anterior cruciate ligament (ACL) tear and ACL reconstruction failure. Anterior closing‐wedge osteotomy (ACWO) decreases the PTS and the risk of reinjury after revision ACL reconstruction. ACWO techniques include supratubercular, transtubercular, or infratubercular. However, there are limitations to the amount of slope correction an ACWO can achieve in the context of a massively abnormal slope. If the necessary slope correction is greater than 20°, a supratubercular ACWO cannot achieve the required correction without high risk of brittle fixation, a transtubercular ACWO would introduce increased morbidity of a secondary osteotomy and change the biomechanics of the patellofemoral joint resulting in significant patella alta, and an infratubercular ACWO would require a major anterior tibial metaphysodiaphyseal resection. The tibial plateau leveling osteotomy (TPLO) is an alternative curved osteotomy commonly used in canines that avoids the adverse events associated with a large ACWO. Further benefits of TPLO for massive slope correction include improved maintenance of native soft‐tissue tension, avoidance of major recurvatum, and the ability to control the correct degree. We describe an open technique for a TPLO to decrease the PTS and the risk of recurrent ACL injury. Technique Video video See video under supplementary data.
Arthroscopic Subpectoral Tenodesis of the Long Head of the Biceps Brachii
Hoffer, Alexander J , Tokish, John M.

Arthroscopy Techniques | June 1, 2024 | Volume: 13 | Issue: 10 | Pages: No page available

10.1016/j.eats.2024.103079 Get It

Abstract The long head of the biceps brachii is a common pain generator in the shoulder that is often managed surgically with tenotomy or tenodesis. The clinical outcomes after tenotomy and tenodesis are comparable. However, tenodesis is preferred in the active population owing to complications associated with tenotomy, including cosmetic deformity, early fatigue, and cramping. Controversy surrounds both the approach and location of tenodesis. Both open and arthroscopic techniques have been described. An arthroscopic approach is used for tenodesis within the intertubercular groove between the humeral head articular margin and superior border of the pectoralis major but has the drawback of pathologic tendon retained in the groove. An open approach is generally reserved for subpectoral tenodesis, which has the advantage of no retained pathologic tendon but has the drawbacks of an open approach. We describe an all‐arthroscopic technique for subpectoral tenodesis of the long head of the biceps brachii at the lower border of the pectoralis major. Technique Video video See video under supplementary data.
Arthroscopic Technique for Headless Compression Screw Fixation of Large Bony Bankart Fractures in Anterior Shoulder Instability
Hoffer, Alexander J , Tummala, Sailesh V. , Tokish, John M. , Tummala, Sailesh V

Arthroscopy Techniques | May 17, 2024 | Volume: 13 | Issue: 8 | Pages: No page available

10.1016/j.eats.2024.103029 Get It

Abstract A bony Bankart fracture is a common injury pattern in anterior shoulder instability. The fracture fragment size varies and the larger the fragment the more likely recurrent instability will occur. When a large bony Bankart fracture is present, surgical fixation is preferred. Both open and arthroscopic approaches exist with multiple fixation techniques including anterior‐to‐posterior screw fixation, suture anchor bridge fixation, and suture button fixation. Arthroscopic screw fixation is difficult, as the angle necessary to be parallel to the glenoid surface requires a far medial start point and places the nerve at risk. The use of a variable‐pitch, headless compression screw placed from posterior to anterior avoids these risks. We describe an arthroscopic technique for glenoid fixation using a posterior‐to‐anterior, cannulated, variable‐pitch headless compression screw for the treatment of an anterior BBF. Technique Video video See video under supplementary data.