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Subramanyan, Ram Kumar

Mayo Clinic

University of Southern California

Citations 2

Abstract 16570: Benchmarking Risk-Adjusted Outcomes in Congenital Heart Surgery
Subramanyan, Ram Kumar, Thibault, Dylan, O’Brien, Sean M. , Shahian, David M. , Bacha, Emile , Badhwar, Vinay , Caldarone, C.A., Fernández, Félix G. , Pasquali, Sara K. , Rainey, Tabitha, Romano, Jennifer C., Shashidharan, Subhadra, Tweddell, James S., Mayer, John E. , Gaynor, J. William , Dearani, Joseph A. , Jacobs, Jeffrey P. , Overman, David M.

Circulation | December 19, 2023 | Volume: 148 | Issue: Suppl_1 | Pages: No page available

10.1161/circ.148.suppl_1.16570 Get It

Background: Robust models exist to predict risk-adjusted mortality following congenital heart surgery. It is known that underlying diagnosis modifies predicted risk of operations, and institution-level outcomes vary based on their unique case mix. We therefore evaluated risk-adjusted outcomes for a subset of diagnosis-procedure (D-P) combinations within the Society of Thoracic Surgeons' (STS) congenital heart surgery database (CHSD). Methods: A clinician panel identified the most frequently encountered D-P combinations in CHSD between 07/2017 and 06/2021. Candidate modeling techniques were compared in a random 80% development cohort. Model performance was assessed using internal and cross-validation calibration, discrimination plots and optimism adjusted C-statistics. The final selected model was evaluated in the 20% validation sample. Results: The chosen subset of D-P combinations represented 45,384 of 87,589 (52%) unique episodes of surgical care in CHSD during this time-period. The development cohort (36,350 episodes) had 1.8% mortality (667 deaths). All candidate models had excellent discrimination with C-statistics ranging from 0.862 to 0.876. The model with the best combination of discrimination, calibration, and clinical face validity was a modified version of the current STS mortality risk model. This version included all current risk model variables with the addition of indicator variables for D-P combinations. In the 20% validation sample (9,034 episodes), this model was well calibrated (Figure) and had excellent discrimination (C = 0.879). Conclusion: We describe a cohort of D-P combinations widely encountered in the STS CHSD. Further, we refined the existing STS CHSD risk model for application to these D-P dyads to derive empirical risk-adjusted benchmark outcomes. This approach will benefit quality improvement efforts at an institutional level and may have implications for publicly reporting congenital heart surgery outcomes.
Pediatric Aerodigestive Medicine: Advancing Collaborative Care for Children With Oropharyngeal Dysphagia
Krasaelap, Amornluck , Sabe, Ramy , Bhardwaj, Vrinda, Lerner, Diana G. , Gold, Benjamin D., Boesch, R. Paul , Allmen, Daniel von, Williams, Dana , Chiou, Eric , DeBoer, Emily M. , Hysinger, Erik B. , Maybee, Jennifer , Khlevner, Julie , Larson, Kara , Morris, Kimberly , Jalali, Lauren , McSweeney, Maireade E. , Greifer, Melanie , Rutter, Michael J. , Williams, Nina, Subramanyan, Ram Kumar, Ryan, Matthew J. , Acra, Sari , Pentiuk, Scott, Friedlander, Joel A. , Sobol, Steven E., Kaul, Ajay , Dorfman, Lev , Darbari, Anil , Prager, Jeremy D. , Rosen, Rachel , Cocjin, Jose, Kumar, S. Ram , Boesch, Richard Paul, Kumar, S Ram , Rosen, Rachel , Duncan, Daniel R. , Faure, Christophe C. , Brigger, Matthew T. , Mousa, Hayat M.

Journal of Pediatric Gastroenterology and Nutrition | July 13, 2023 | Volume: 77 | Issue: 4 | Pages: 460-467

10.1097/mpg.0000000000003882 Get It

Objectives:Aerodigestive disorders encompass various pathological conditions affecting the lungs, upper airway, and gastrointestinal tract in children. While advanced care has primarily occurred in specialty centers, many children first present to general pediatric gastroenterologists with aerodigestive symptoms necessitating awareness of these conditions. At the 2021 Annual North American Society for Pediatric Gastroenterology, Hepatology and Nutrition meeting, the aerodigestive Special Interest Group held a full‐day symposium entitled, Pediatric Aerodigestive Medicine: Advancing Collaborative Care of Children with Aerodigestive Disorders. The symposium aimed to underline the significance of a multidisciplinary approach to achieve better outcomes for these complex patients.Methods:The symposium brought together leading experts to highlight the growing aerodigestive field, promote new scientific and therapeutic strategies, share the structure and benefits of a multidisciplinary approach in diagnosing common and rare aerodigestive disorders, and foster multidisciplinary discussion of complex cases while highlighting the range of therapeutic and diagnostic options. In this article, we showcase the diagnostic and therapeutic approach to oropharyngeal dysphagia (OPD), one of the most common aerodigestive conditions, emphasizing the role of a collaborative model.Conclusions:The aerodigestive field has made significant progress and continues to grow due to a unique multidisciplinary, collaborative model of care for these conditions. Despite diagnostic and therapeutic challenges, the multidisciplinary approach has enabled and greatly improved efficient, high‐quality, and evidence‐based care for patients, including those with OPD.