Back to Authors

Khlevner, Julie

https://orcid.org/0000-0001-8166-0382

Mayo Clinic

Columbia University

Citations 3

Autoimmune gastrointestinal dysmotility following SARS-CoV-2 infection successfully treated with intravenous immunoglobulin (P14-1.007)
Montalvo, Mayra , Nallapaneni, Padmini, Hassan, Sara , Khlevner, Julie , Nurko, Samuel , Pittock, Sean J.

Neurology | December 6, 2023 | Volume: 98 | Issue: 18_supplement | Pages: No page available

10.1212/wnl.98.18_supplement.3273 Get It

Pediatric Aerodigestive Medicine: Advancing Collaborative Care for Children With Oropharyngeal Dysphagia
Krasaelap, Amornluck , Sabe, Ramy , Bhardwaj, Vrinda, Lerner, Diana G. , Gold, Benjamin D., Boesch, R. Paul , Allmen, Daniel von, Williams, Dana , Chiou, Eric , DeBoer, Emily M. , Hysinger, Erik B. , Maybee, Jennifer , Khlevner, Julie , Larson, Kara , Morris, Kimberly , Jalali, Lauren , McSweeney, Maireade E. , Greifer, Melanie , Rutter, Michael J. , Williams, Nina, Subramanyan, Ram Kumar, Ryan, Matthew J. , Acra, Sari , Pentiuk, Scott, Friedlander, Joel A. , Sobol, Steven E., Kaul, Ajay , Dorfman, Lev , Darbari, Anil , Prager, Jeremy D. , Rosen, Rachel , Cocjin, Jose, Kumar, S. Ram , Boesch, Richard Paul, Kumar, S Ram , Rosen, Rachel , Duncan, Daniel R. , Faure, Christophe C. , Brigger, Matthew T. , Mousa, Hayat M.

Journal of Pediatric Gastroenterology and Nutrition | July 13, 2023 | Volume: 77 | Issue: 4 | Pages: 460-467

10.1097/mpg.0000000000003882 Get It

Objectives:Aerodigestive disorders encompass various pathological conditions affecting the lungs, upper airway, and gastrointestinal tract in children. While advanced care has primarily occurred in specialty centers, many children first present to general pediatric gastroenterologists with aerodigestive symptoms necessitating awareness of these conditions. At the 2021 Annual North American Society for Pediatric Gastroenterology, Hepatology and Nutrition meeting, the aerodigestive Special Interest Group held a full‐day symposium entitled, Pediatric Aerodigestive Medicine: Advancing Collaborative Care of Children with Aerodigestive Disorders. The symposium aimed to underline the significance of a multidisciplinary approach to achieve better outcomes for these complex patients.Methods:The symposium brought together leading experts to highlight the growing aerodigestive field, promote new scientific and therapeutic strategies, share the structure and benefits of a multidisciplinary approach in diagnosing common and rare aerodigestive disorders, and foster multidisciplinary discussion of complex cases while highlighting the range of therapeutic and diagnostic options. In this article, we showcase the diagnostic and therapeutic approach to oropharyngeal dysphagia (OPD), one of the most common aerodigestive conditions, emphasizing the role of a collaborative model.Conclusions:The aerodigestive field has made significant progress and continues to grow due to a unique multidisciplinary, collaborative model of care for these conditions. Despite diagnostic and therapeutic challenges, the multidisciplinary approach has enabled and greatly improved efficient, high‐quality, and evidence‐based care for patients, including those with OPD.
Autoimmune gastrointestinal dysmotility following SARS‐CoV‐2 infection successfully treated with intravenous immunoglobulin
Montalvo, Mayra , Nallapaneni, Padmini, Hassan, Sara , Pittock, Sean J. , Khlevner, Julie , Nurko, Samuel , Pittock, S J , Nurko, Samuel

Neurogastroenterology & Motility | January 5, 2022 | Volume: 34 | Issue: 7 | Pages: No page available

10.1111/nmo.14314 Get It

AbstractBackgroundAutoimmune gastrointestinal dysmotility (AGID) is a limited form of dysautonomia that can be paraneoplastic or idiopathic. Some presentations can be preceded by a viral infection.MethodsWe report a case of a 17‐year‐old girl that developed intractable nausea and early satiety after SARS‐CoV‐2 infection.Key resultsOver ten months, she required nasogastric and nasoduodenal tube feedings and finally was advanced to total parenteral nutrition to meet her caloric needs. Her α3 nicotinic ganglionic acetylcholine and anti‐striational antibodies were mildly elevated.Gastrointestinal transit scintigraphy studies showed delayed gastric emptying and slowed small bowel transit. Thermoregulatory sweat test showed areas of anhidrosis consistent with autonomic sudomotor impairment. After IVIG treatment the patient's symptoms improved dramatically and she was able to tolerate full oral diet. This was reflected by improvement of her baseline transit studies and the thermoregulatory sweat test.Conclusions and inferencesThis is the first report of AGID occurring after SARS‐CoV‐2 infection. The dramatic response to IVIG emphasizes the importance of early recognition and the reversible and treatable nature of this condition.