Citations 2
Gluten‐free schooling: Navigating challenges and triumphs for children with celiac disease
Weisbrod, Vanessa , Khavari, Nasim, Absah, Imad , Mallon, Danny, Raber, Catherine , Badalyan, Vahe , Shull, Mary , Dunn, Ashley R., Wren, Anava, Mardini, Farah, Fahey, Lisa M. , Ediger, Tracy , Leonard, Maureen M. , López-Rivera, Javier A. , Jericho, Hilary , Jericho, Hilary , Weisbrod, Vanessa , Lee, Dale Young , Verma, Ritu , Dunn, Ashley, Silvester, Jocelyn A.
JPGN Reports | March 11, 2025 | Volume: 6 | Issue: 2 | Pages: 99-106
ABSTRACTObjectivesCeliac disease (CeD), an autoimmune disorder triggered by gluten ingestion, induces intestinal inflammation and varied symptoms. Treatment entails a strict gluten‐free diet (GFD), posing challenges for students, especially in schools with limited food choices. Nonadherence worsens symptoms, yet research on CeD's impact on students is scarce.MethodsThe CeliacKIDS study, conducted across 11 United States academic medical centers, evaluated gluten exposure risk in pediatric CeD patients via a cross‐sectional survey from August 2020 to August 2021. Participants recruited from treating institutions were approved by respective Institutional Review Boards.ResultsOne hundred and sixty children aged 5–18 (65% female, 34% male, 1% other) participated. Only 12% had GF food options at school, 31% brought their own for celebrations, and 41% lacked gluten free (GF) snacks after school. Thirty‐six percent lacked a 504 plan, with 5% misinformed. Hand hygiene concerns included 24% using sanitizer and 10% rarely washing hands before eating. Sixty‐two percent disclosed CeD, 35% when prompted, and 3% refused, mainly 13‐year‐old males. Two percent hesitated to request GF options, and 2% consumed potentially gluten‐containing food from friends.ConclusionMany US schools provide GF accommodations under the Americans with Disabilities Act (ADA) but lack national standards. Diverse GF options and education on GF‐safe practices are crucial for GFD adherence. Discrepancies in parent–child perceptions emphasize the need for better communication. Adolescents, particularly females aged 12–13 with 2+ years on a GF diet, face higher risks. Transparent family–school communication is vital for optimizing the school experience and ensuring GFD adherence. Comprehensive nationwide school training is essential for celiac patients' well‐being.
Efficacy and Outcomes of Faecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection in Children with Inflammatory Bowel Disease
Nicholson, Maribeth R. , Alexander, Erin, Ballal, Sonia, Davidovics, Zev, Docktor, Michael , Dole, Michael , Gisser, Jonathan M., Goyal, Alka , Hourigan, Suchitra K. , Jensen, M. Kyle , Kaplan, Jess L. , Kelsen, Judith R. , Khanna, Sahil , Knackstedt, Elizabeth D , Lentine, Jennifer, Lewis, Jeffery D., Michail, Sonia , Mitchell, Paul D. , Patton, Tiffany , Queliza, Karen , Sidhu, Sarah , Solomon, Aliza , Suskind, David L. , Weatherly, Madison, Werlin, Steven L. , Zoeten, Edwin F. de , Kahn, Stacy A. , Group, North American Society of Pediatric Gastroenterology and Nutrition Faecal Microbiota Transplantation Special Interest, Aktay, Nur, Asbah, Imad, Bassett, Mikelle, Brumbaugh, David , Caicedo, Luis A. , Chawla, Anu, Conrad, Máire , Dykes, Chelly Dana, Grzywacz, Kelly, Gulati, Ajay, Gurram, Bhaskar , Hellman, Jenny, Kastl, Art, Mallon, Danny, Pai, Nikhil , Pasternak, Brad , Prozialeck, Josh, Reilly, Norelle R., Russell, George H., Singh, Namita , Small‐Harary, Lesley , Sood, Shilpa , Stumphy, Jessica, Sullivan, Jill M., Syed, Sabeen, Titgemeyer, Cebie, Townsend, Pete, Zheng, Yuhua , Suskind, David L , Alexander, Erin, Kellermayer, Richárd , Kennedy, Melissa A, Oliva‐Hemker, Maria , Group, North American Society of Pediatric Gastroenterology and Nutrition Faecal Microbiota Transplantation Special Interest, Bartlett, Mark, Caicedo, Luis, Gulati, Ajay, Patel, Ashish , Prozialeck, Joshua D. , Sood, Shilpa, Sullivan, Jill
Journal of Crohn's and Colitis | November 8, 2021 | Volume: 16 | Issue: 5 | Pages: 768-777
Abstract Background Children with inflammatory bowel disease [IBD] are disproportionally affected by recurrent Clostridioides difficile infection [rCDI]. Although faecal microbiota transplantation [FMT] has been used with good efficacy in adults with IBD, little is known about outcomes associated with FMT in paediatric IBD. Methods We performed a retrospective review of FMT at 20 paediatric centres in the USA from March 2012 to March 2020. Children with and without IBD were compared with determined differences in the efficacy of FMT for rCDI. In addition, children with IBD with and without a successful outcome were compared with determined predictors of success. Safety data and IBD-specific outcomes were obtained. Results A total of 396 paediatric patients, including 148 with IBD, were included. Children with IBD were no less likely to have a successful first FMT then the non-IBD affected cohort [76% vs 81%, p = 0.17]. Among children with IBD, patients were more likely to have a successful FMT if they received FMT with fresh stool [p = 0.03], were without diarrhoea prior to FMT [p = 0.03], or had a shorter time from rCDI diagnosis until FMT [p = 0.04]. Children with a failed FMT were more likely to have clinically active IBD post-FMT [p = 0.002] and 19 [13%] patients had an IBD-related hospitalisation in the 3-month follow-up. Conclusions Based on the findings from this large US multicentre cohort, the efficacy of FMT for the treatment of rCDI did not differ in children with IBD. Failed FMT among children with IBD was possibly related to the presence of clinically active IBD.