Torres, Marco Antônio Rodrigues

Mayo Clinic

9th July Hospital, DASA, San Paolo 04122-000, Brazil

Citations 2

Stress Echo 2030: The Novel ABCDE-(FGLPR) Protocol to Define the Future of Imaging

Pepi, Mauro , Ciampi, Quirino , Cortigiani, Lauro , Arruda‐Olson, Adelaide M. , Daros, Clarissa Borguezan , Pretto, José Luis de Castro e Silva , Bossone, Eduardo , Merli, Elisa , Kane, Garvan C. , Scali, Maria Chiara, Morrone, Doralisa , Simova, Iana , Samardjieva, Martina, Boshchenko, A , Ryabova, T. R. , Pálinkás, Eszter Dalma , Sepp, Róbert , Torres, Marco Antônio Rodrigues , Villarraga, Hector R. , Kovačević-Preradović, Tamara , Citro, Rodolfo , Amor, Miguel , Mosto, Hugo , Salamè, Michael, Leeson, Paul , Gaibazzi, Nicola , Tuttolomondo, Domenico , Prota, Costantina , Peteiro, Jesús , Heyning, Caroline M. Van De , D’Andrea, Antonello , Rigo, Fausto , Ostojić, Miodrag , Arbucci, Rosina , Haber, Diego M. Lowenstein, Merlo, Pablo , Wierzbowska‐Drabik, Karina , Kasprzak, Jarosław D. , Haberka, Maciej , Ratanasit, Nithima , Mori, Fabio , D’Alfonso, Maria Grazia , Tassetti, Luigi , Milazzo, Alessandra , Olivotto, Iacopo , Marchi, Alberto, Rodríguez‐Zanella, Hugo , Zagatina, A , Padang, Ratnasari , Dekleva, Milica , Djordievic-Dikic, Ana, Boskovic, N , Tešić, Milorad , Giga, Vojislav , Salvo, Giovanni Di , Lorenzoni, Valentina , Cameli, Matteo , Bombardini, Tonino, Caso, Pio, Čelutkienė, Jelena , Barbieri, Andréa , Benfari, Giovanni , Bartolacelli, Ylenia , Malagoli, Alessandro , Mantovani, Francesca , Villari, Bruno, Russo, Antonello , Nes, Michele De, Carpeggiani, Clara , Monte, Ines , Re, Federica , Cotrim, Carlos , Bilardo, G, Karužas, Arnas , Matuliauskas, D, Colonna, Paolo , Antonini‐Canterin, Francesco, Pellikka, Patricia A. , (SIECVI), The Stress Echo 2030 Study Group of the Italian Society of Echocardiography and Cardiovascular Imaging, Borguezan-Daros, Clarissa , de Castro E Silva Pretto, José Luis , Bossone, Eduardo , Morrone, Doralisa , Palinkas, Eszter Dalma , Preradović, Tamara Kovačević , Tuttolomondo, Domenico , Peteiro, Jesus , Van De Heyning, Caroline M , D'Andrea, Antonello , Arbucci, Rosina , Wierzbowska-Drabik, Karina , Tassetti, Luigi , Olivotto, Iacopo , Rodriguez-Zanella, Hugo , Tesic, Milorad , Di Salvo, Giovanni , Cameli, Matteo , Mandoli, Giulia Elena , Barbieri, Andrea , Benfari, Giovanni , Bartolacelli, Ylenia , Malagoli, Alessandro , Mantovani, Francesca , Monte, Ines , Cotrim, Carlos , Karuzas, Arnas , Colonna, Paolo , Pepi, Mauro , Pellikka, Patricia A , Ciampi, Quirino , Zagatina, Angela , Kasprzak, Jaroslaw D , Ryabova, Tamara , Gaibazzi, Nicola , Lorenzoni, Valentina , Citro, Rodolfo , Boshchenko, Alla , Celutkiene, Jelena , Cocchia, Rosangela , Varga, Albert , Ágoston, Gergely , Vrublevsky, A. V. , Pálinkás, Attila , Mangia, Cristina , Nikolic, Aleksandra, Lowenstein, Jorge , Camarozano, Ana Cristina , Marchi, Alberto, Beleslin, Branko , Bursi, Francesca , Saad, Ariel K. , (SIECVI), The Stress Echo 2030 Study Group of the Italian Society of Echocardiography and Cardiovascular Imaging

Journal of Clinical Medicine | August 17, 2021 | Volume: 10 | Issue: 16 | Pages: 3641

With stress echo (SE) 2020 study, a new standard of practice in stress imaging was developed and disseminated: the ABCDE protocol for functional testing within and beyond CAD. ABCDE protocol was the fruit of SE 2020, and is the seed of SE 2030, which is articulated in 12 projects: 1-SE in coronary artery disease (SECAD); 2-SE in diastolic heart failure (SEDIA); 3-SE in hypertrophic cardiomyopathy (SEHCA); 4-SE post-chest radiotherapy and chemotherapy (SERA); 5-Artificial intelligence SE evaluation (AI-SEE); 6-Environmental stress echocardiography and air pollution (ESTER); 7-SE in repaired Tetralogy of Fallot (SETOF); 8-SE in post-COVID-19 (SECOV); 9: Recovery by stress echo of conventionally unfit donor good hearts (RESURGE); 10-SE for mitral ischemic regurgitation (SEMIR); 11-SE in valvular heart disease (SEVA); 12-SE for coronary vasospasm (SESPASM). The study aims to recruit in the next 5 years (2021–2025) ≥10,000 patients followed for ≥5 years (up to 2030) from ≥20 quality-controlled laboratories from ≥10 countries. In this COVID-19 era of sustainable health care delivery, SE2030 will provide the evidence to finally recommend SE as the optimal and versatile imaging modality for functional testing anywhere, any time, and in any patient.

Hemodynamic Heterogeneity of Reduced Cardiac Reserve Unmasked by Volumetric Exercise Echocardiography

Bombardini, Tonino, Zagatina, A , Ciampi, Quirino , Arbucci, Rosina , Merlo, Pablo , Haber, Diego M. Lowenstein, Morrone, Doralisa , Djordjevic‐Dikic, Ana , Tešić, Milorad , Boskovic, N , Giga, Vojislav , Pretto, José de Castro e Silva, Daros, Clarissa Borguezan , Amor, Miguel , Mosto, Hugo , Salamè, Michael, Citro, Rodolfo , Simova, Iana , Samardjieva, Martina, Wierzbowska‐Drabik, Karina , Kasprzak, Jarosław D. , Gaibazzi, Nicola , Cortigiani, Lauro , Scali, Maria Chiara, Antonini‐Canterin, Francesco, Torres, Marco Antônio Rodrigues , Nes, Michele De, Ostojić, Miodrag , Carpeggiani, Clara , Arruda‐Olson, Adelaide M. , Pellikka, Patricia A. , Imaging, on behalf of the Stress Echo 2020 Study Group of the Italian Society of Cardiovascular, D'Andrea, Antonello , Tesic, Milorad , Amor, Miguel , Monte, Ines , Pellikka, Patricia A , Ciampi, Quirino , Zagatina, Angela , Wierzbowska-Drabik, Karina , Kasprzak, Jaroslaw D , Gaibazzi, Nicola , Morrone, Doralisa , Arbucci, Rosina , Citro, Rodolfo , D’Andrea, Antonello , Beleslin, Branko , Pretto, José Luis de Castro e Silva , Monte, Ines , Pepi, Mauro , Kovačević-Preradović, Tamara , Lowenstein, Jorge , Imaging, on behalf of the Stress Echo 2020 Study Group of the Italian Society of Cardiovascular

Journal of Clinical Medicine | June 29, 2021 | Volume: 10 | Issue: 13 | Pages: 2906

10.3390/jcm10132906

Background: Two-dimensional volumetric exercise stress echocardiography (ESE) provides an integrated view of left ventricular (LV) preload reserve through end-diastolic volume (EDV) and LV contractile reserve (LVCR) through end-systolic volume (ESV) changes. Purpose: To assess the dependence of cardiac reserve upon LVCR, EDV, and heart rate (HR) during ESE. Methods: We prospectively performed semi-supine bicycle or treadmill ESE in 1344 patients (age 59.8 ± 11.4 years; ejection fraction = 63 ± 8%) referred for known or suspected coronary artery disease. All patients had negative ESE by wall motion criteria. EDV and ESV were measured by biplane Simpson rule with 2-dimensional echocardiography. Cardiac index reserve was identified by peak-rest value. LVCR was the stress-rest ratio of force (systolic blood pressure by cuff sphygmomanometer/ESV, abnormal values ≤2.0). Preload reserve was defined by an increase in EDV. Cardiac index was calculated as stroke volume index * HR (by EKG). HR reserve (stress/rest ratio) <1.85 identified chronotropic incompetence. Results: Of the 1344 patients, 448 were in the lowest tertile of cardiac index reserve with stress. Of them, 303 (67.6%) achieved HR reserve <1.85; 252 (56.3%) had an abnormal LVCR and 341 (76.1%) a reduction of preload reserve, with 446 patients (99.6%) showing ≥1 abnormality. At binary logistic regression analysis, reduced preload reserve (odds ratio [OR]: 5.610; 95% confidence intervals [CI]: 4.025 to 7.821), chronotropic incompetence (OR: 3.923, 95% CI: 2.915 to 5.279), and abnormal LVCR (OR: 1.579; 95% CI: 1.105 to 2.259) were independently associated with lowest tertile of cardiac index reserve at peak stress. Conclusions: Heart rate assessment and volumetric echocardiography during ESE identify the heterogeneity of hemodynamic phenotypes of impaired chronotropic, preload or LVCR underlying a reduced cardiac reserve.