Back to Authors

Denard, Patrick J.

https://orcid.org/0000-0002-2641-5920

Mayo Clinic

Oregon Shoulder Institute Medford Oregon U.S.A

Citations 7

Compression of an Autograft Biceps Into an Augmentation Patch Does Not Cause Mechanical Damage to the Tenocyte
Brinkman, Joseph C. , Makovicka, Justin L. , Denard, Patrick J. , Colbath, Gregory, Mercuri, Jeremy , Tokish, John M., Denard, Patrick J

Arthroscopy | September 26, 2024 | Volume: 41 | Issue: 6 | Pages: 1745-1751

10.1016/j.arthro.2024.09.029 Get It

Purpose To evaluate the effects of this graft preparation technique on histologic evidence of tenocyte mechanical damage. Methods A consecutive series of patients undergoing biceps tenodesis for shoulder pathology were evaluated. After suprapectoral tenodesis, 27 mm of the long head of the biceps was secured for compression into the patch. The remaining length of the residual tendon was longitudinally split, resulting in 2 equal lengths of remnant tendon from the same zone. One sample was sent to pathology with no preparation, and the other was prepared as a compressed biceps autograft patch according to the manufacturer’s recommendations. Both grafts were sent to pathology for evaluation of tenocyte morphology. Records were reviewed to determine if compression resulted in mechanical damage to the tenocytes at the time of biceps augmentation. Results Fifty‐five shoulder procedures and 110 samples were sent for pathology analysis. Forty‐two of the 55 (76%) specimens demonstrated morphologically normal tenocytes in both the compressed and noncompressed groups, and 7 (13%) cases showed evidence of tenocyte necrosis or mechanical damage in both groups. The difference in abnormal tenocyte morphology between the compressed and native groups was not statistically significant ( P = .625). Conclusions Autograft biceps compression into a point‐of‐care patch did not result in mechanical damage to tenocyte morphology at the time of insertion for augmentation of rotator cuff pathology. Clinical Relevance Free proximal biceps tendon compression can result in a patch that does not mechanically damage the tenocyte. The patch can be used as a biologic autograft to enhance shoulder rotator cuff repair, as well as subscapularis repair in the setting of shoulder arthroplasty.
Poster 398: Patient Perceptions of Social Media Use by Orthopaedic Surgeons: Comparing Responses Across the US
Wharton, Benjamin R. , Smyth, Anthony, Bravman, Jonathan T. , Tokish, John M. , McCarty, Eric C. , Frank, Rachel M , Denard, Patrick J. , Westermann, Robert W. , Duchman, Kyle R.

Orthopaedic Journal of Sports Medicine | September 20, 2024 | Volume: 12 | Issue: 7_suppl2 | Pages: No page available

10.1177/2325967124s00367 Get It

Objectives: The purpose of this study was to characterize content posted by orthopaedic surgeons on social media (SM) while investigating patient perceptions of this content from various regions of the United States. Analysis was included regarding how this content may influence the respondents’ healthcare decisions. Methods: SM posts by orthopaedic surgeons were reviewed and categorized. A patient survey was written to assess respondent SM usage practices as well as respondent perceptions of these categories. The survey was administered in the clinic of 13 separate orthopaedic surgeons via QR code. Survey results were analyzed for differences in SM utilization. Patient responses were assessed to judge perception of social medial content types. Results: There were 674 completed patient surveys. The 18-24 (89.3%) and 25-34 (87.6%) age groups were more likely to report daily use (p=0.002), but SM utilization was high among all age groups. 23% of patients reported using SM to see information about their healthcare at least once per month, 38% of patients reported reviewing the SM account of a physician at least once per month, and 23% of patients reported that they were likely or very likely to view the SM account of their own physician. 26% of patients reported that SM content is likely or very likely to influence which physician they see. Patients held the most consistently positive view of posts educating patients regarding common injuries, discussing sports team coverage, providing patient testimonials, and posts illustrating examples of imaging used to diagnose and treat patients. Patients held consistently neutral views of posts educating colleagues, discussing research and presentations at national meetings, displaying aspects of surgeons’ personal lives, and supporting marginalized groups. Several post categories elicited negative or highly polarized responses including those discussing research publications, showing surgical techniques or pictures/videos taken during surgery, or political statements. Conclusions: SM is an increasingly useful tool to help physicians interact with patients or build a practice. Physicians who wish to interact with patients should consider posting content viewed most positively including posts educating patients, discussing sports team coverage, and patient testimonials. Content that is viewed less favorably should be posted sparingly or with a sensitive tag. The most effective way to reach large patient populations appears to be through Instagram, Facebook, Tik Tok, Snapchat, and LinkedIn, in that order. Further ongoing study is required to understand the differences between physician SM content focused on interacting with patients compared to content focused on interacting with other physicians.
Identification of ChatGPT‐Generated Abstracts Within Shoulder and Elbow Surgery Poses a Challenge for Reviewers
Stadler, Ryan D. , Sudah, Suleiman Y. , Denard, Patrick J. , Duralde, Xavier A. , Garrigues, Grant E. , Klifto, Christopher S. , Namdari, Surena , Sánchez‐Sotelo, Joaquín , Menendez, Mariano E. , Sanchez-Sotelo, Joaquin, Sanchez-Sotelo, J. , Denard, Patrick J , Moverman, Michael A. , Levy, Jonathan C., Menendez, Mariano E.

Arthroscopy | July 9, 2024 | Volume: 41 | Issue: 4 | Pages: 916

10.1016/j.arthro.2024.06.045 Get It

Purpose To evaluate the extent to which experienced reviewers can accurately discern between artificial intelligence (AI)–generated and original research abstracts published in the field of shoulder and elbow surgery and compare this with the performance of an AI detection tool. Methods Twenty‐five shoulder‐ and elbow‐related articles published in high‐impact journals in 2023 were randomly selected. ChatGPT was prompted with only the abstract title to create an AI‐generated version of each abstract. The resulting 50 abstracts were randomly distributed to and evaluated by 8 blinded peer reviewers with at least 5 years of experience. Reviewers were tasked with distinguishing between original and AI‐generated text. A Likert scale assessed reviewer confidence for each interpretation, and the primary reason guiding assessment of generated text was collected. AI output detector (0%‐100%) and plagiarism (0%‐100%) scores were evaluated using GPTZero. Results Reviewers correctly identified 62% of AI‐generated abstracts and misclassified 38% of original abstracts as being AI generated. GPTZero reported a significantly higher probability of AI output among generated abstracts (median, 56%; interquartile range [IQR], 51%‐77%) compared with original abstracts (median, 10%; IQR, 4%‐37%; P < .01). Generated abstracts scored significantly lower on the plagiarism detector (median, 7%; IQR, 5%‐14%) relative to original abstracts (median, 82%; IQR, 72%‐92%; P < .01). Correct identification of AI‐generated abstracts was predominately attributed to the presence of unrealistic data/values. The primary reason for misidentifying original abstracts as AI was attributed to writing style. Conclusions Experienced reviewers faced difficulties in distinguishing between human and AI‐generated research content within shoulder and elbow surgery. The presence of unrealistic data facilitated correct identification of AI abstracts, whereas misidentification of original abstracts was often ascribed to writing style. Clinical Relevance With rapidly increasing AI advancements, it is paramount that ethical standards of scientific reporting are upheld. It is therefore helpful to understand the ability of reviewers to identify AI‐generated content.
Paper 50: Biceps Autograft Patch Augmentation for Rotator Cuff Repair: The Effect of Point of Care Compression on Tenocyte Viability.
Colbath, Gregory, Tokish, John M. , Mercuri, Jeremy , Denard, Patrick J.

Orthopaedic Journal of Sports Medicine | July 31, 2023 | Volume: 11 | Issue: 7_suppl3 | Pages: No page available

10.1177/2325967123s00075 Get It

Objectives: Augmentation of rotator cuff repair in patients at risk for retear has gained popularity. These techniques have generally consisted of allograft and xenograft patches. Recently, use of an autograft biceps from the normally discarded portion after biceps tenodesis was described as a potential patch for rotator cuff repair augmentation. As an autograft, it is free and readily available. The original description prepared the patch by placing it through a commercial skin graft preparation station. This technique results in a significant decrease in tenocyte viability, however, and results in a patch that is difficult to work with. Recently, an autograft compression plate has been employed to use as a point of care processor for adapting the discarded long head of the biceps after tenodesis into an autograft patch. The purpose of this study was to evaluate the feasibility of this point of care graft preparation method, and to specifically evaluate its effect on tenocyte viability in patients undergoing patch augmentation for rotator cuff repair. Methods: We reviewed the medical records of consecutive patients who underwent biceps tenodesis for either rotator cuff repair or anatomic shoulder arthroplasty. After tenodesis, and after 27 mm of the long head of the biceps was secured for compression into the patch, the remaining length of normally discarded tendon was longitudinally split, resulting in 2 equal lengths of remnant tendon from the same zone of the tendon. One sample was sent to pathology with no preparation, and the other was prepared as a biceps autograft patch using the autograft compression plate according to the manufacturer’s recommendations. Once prepared, this second biceps sample was sent to pathology along with the first. The request was to evaluate for tenocyte viability. Pathologists were not told which sample was compressed. Records were reviewed to determine if biceps tendon samples were viable at the time of harvest, and whether the compression process affected a change between the first and second specimen. Results: 20 consecutive patients were reviewed. All 20 biceps produced usable patches. The remnant biceps samples that were sent to pathology revealed the following: Sixteen of the 20 patients had biceps tenocyte viability that were read out as completely normal in both the compressed and non compressed samples. Of the 4 patients that did show some degree of tenocyte necrosis or death, 3 of the patients had identical findings between the compressed and non-compressed samples. Only 1/20 (5%) of the patients showed a difference between the compressed sample and the non-compressed sample, with the compressed sample demonstrating small areas of “patchy necrosis” while the non compressed sample showed normal tendon in that specimen. Conclusions: Compression of the long head of the biceps results in an autograft patch that is a promising option in rotator cuff augmentation. The method of compression plating to process the long head of the biceps remnant into an augmentation patch appears to have no significant effect on tenocyte viability, suggesting that the patch has live tenocytes at the time of point of care augmentation.
Compressed Biceps Autograft Augmentation of Arthroscopic Rotator Cuff Repair
Tokish, John M. , Shaha, James S., Denard, Patrick J. , Mercuri, Jeremy , Colbath, Gregory, Denard, Patrick J

Arthroscopy Techniques | October 20, 2022 | Volume: 11 | Issue: 11 | Pages: No page available

10.1016/j.eats.2022.08.011 Get It

Abstract Rotator cuff repair failure rates continue to be a challenging problem. Various methods of biological and structural augmentation of the rotator cuff have been explored to improve tendon healing after repair. We describe a technique in which biceps tendon autograft is harvested after tenodesis. The biceps tendon is then compressed into a patch that is placed over the repaired rotator cuff tendon. Repurposing the portion of the tendon that is otherwise discarded offers several advantages over other augmentations that have been used, including the biological potential of live autograft tenocytes in the patch, lower cost, and no donor‐site morbidity. Technique Video video See video under supplementary data.
The addition of preoperative three-dimensional analysis alters implant choice in shoulder arthroplasty
Werner, Brian C. , Denard, Patrick J. , Tokish, John M. , Bedi, Asheesh , Donegan, Ryan P., Metcalfe, Nick, Denard, Patrick J , Dines, Joshua S.

Shoulder & Elbow | February 2, 2021 | Volume: 14 | Issue: 4 | Pages: 378-384

10.1177/1758573221989306 Get It

Background The primary objective of the present study was to investigate how preoperative imaging modalities including 3D computed tomography (CT) scans with preoperative planning software affect implant choice for shoulder arthroplasty. Methods X-ray, uncorrected 2D CT scans, and 3D CT scans from 21 patients undergoing primary arthroplasty were reviewed by five shoulder surgeons. Each surgeon measured glenoid version, inclination and humeral head subluxation, and then selected an anatomic or reverse shoulder arthroplasty implant based only on these imaging parameters. Each surgeon virtually positioned the implant. Agreement between surgeons and changes in plan for individual surgeons between imaging modalities were assessed. Results Average measurements of native version, inclination, and subluxation were similar across all imaging modalities with very good interobserver reliability. Overall, there was a high rate of variability in choice of implant depending on imaging modality. Agreement on implant selection between surgeons improved from 68.6% using x-ray to 80.0% with 3D CT. Introducing age added significant variability, reducing agreement on implant choice to 61.0% with 3D CT. Conclusions The use of preoperative 3D planning changes implant choice in nearly one-third of cases compared to plain radiographs and improves surgeon agreement on implant choice compared to x-ray and 2D CT. Level of evidence: III.
Radiographic parameters associated with excellent versus poor range of motion outcomes following reverse shoulder arthroplasty
Lädermann, Alexandre , Parsons, Bradford O. , Tokish, John M. , Denard, Patrick J. , Lädermann, Alexandre , Lädermann, Alexandre , Denard, Patrick J , Haidamous, Georges , Hartzler, Robert U. , Lederman, Evan

Shoulder & Elbow | July 10, 2020 | Volume: 14 | Issue: 1 | Pages: 39-47

10.1177/1758573220936234 Get It

Background The purpose was to evaluate the relationship of component size and position to postoperative range of motion following reverse shoulder arthroplasty. The hypothesis was that increased lateralization, larger glenospheres, and a decreased acromiohumeral distance would be associated with excellent postoperative range of motion. Methods A retrospective multicenter study was performed at a minimum of one year postoperatively on 160 patients who underwent primary reverse shoulder arthroplasty with a 135° humeral component. Outcomes were stratified based on postoperative forward flexion and external rotation into excellent ( n = 42), defined as forward flexion >140° and external rotation > 30°, or poor ( n = 36), defined as forward flexion <100° and external rotation < 15°. Radiographic measurements and component features were compared between the two groups. Results A larger glenosphere size was associated with an excellent outcome ( p = 0.009). A 2-mm posterior offset humeral cup ( p = 0.012) and an increased inferior glenosphere overhang (3.1 mm vs 1.4 mm; p = 0.002) were also associated with excellent outcomes. Humeral lateralization and distalization were not associated with an excellent outcome. Conclusion: Larger glenosphere size and inferior positioning as well as posterior humeral offset are associated with improved postoperative range of motion following reverse shoulder arthroplasty. Level of Evidence Level 3, retrospective comparative study.