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Crook, Richard

https://orcid.org/0000-0001-6782-1581

Mayo Clinic

Mayo Clinic in Florida

Citations 10

Clinical, genetic, and neuropathologic characteristics of posterior cortical atrophy
Tang‐Wai, David F. , Graff-Radford, N. R., Parisi, Joseph E., Caselli, Richard J. , Petersen, Ronald , Boeve, Bradley F. , Dickson, Dennis W. , Crook, Richard , Knopman, David S.

Neurology | May 13, 2012 | Volume: 63 | Issue: 7 | Pages: 1168-1174

10.1212/01.wnl.0000140289.18472.15 Get It

An Iranian family with Alzheimer’s disease caused by a novel APP mutation (Thr714Ala)
Najmabadi, Hossein , Noorian, Ali Reza , Moghimi, Babak, Jannati, Ali , Soltanzadeh, A., Krefft, Thomas A., Hardy, John , Pasalar, Parvin , Crook, Richard , Hardy, John

Neurology | May 13, 2012 | Volume: 58 | Issue: 10 | Pages: 1574-1575

10.1212/wnl.58.10.1574 Get It

A kindred with Parkinson’s disease not showing genetic linkage to established loci
Gwinn, Katrina , Lincoln, S., Caviness, John N., Hardy, John , Farrer, Matthew J. , Crook, Richard , Adler, Charles H. , Hardy, John

Neurology | May 13, 2012 | Volume: 54 | Issue: 2 | Pages: 504-504

10.1212/wnl.54.2.504 Get It

P1‐185: Wild‐type human TDP‐43 induces mitochondrial abnormalities and axonal degeneration in transgenic mice
Xu, Yafei , Lin, Wen-Lang, D’Alton, Simon , Sheng, Hong, Casey, Monica Castanedes, Tong, Jimei, Yu, Xin , Rademakers, Rosa , Hutton, Mike, Petrucelli, Leonard , Lewis, Jada , Gendron, Tania F. , Zhang, Yong‐Jie , Sheng, Hong, Crook, Richard , Knight, Joshua A. , Boylan, Khrista , McGowan, Eileen , Dickson, Dennis W.

Alzheimer's & Dementia | July 11, 2010 | Volume: 6 | Issue: 4S_Part_8 | Pages: No page available

10.1016/j.jalz.2010.05.735 Get It

P4‐047: Use of a wild‐type tauopathy model to generate a novel Alzheimer model
Adams, Stephanie J. , McBride, Melinda, Crook, Richard , Dickson, Dennis W.

Alzheimer's & Dementia | June 25, 2009 | Volume: 5 | Issue: 4S_Part_15 | Pages: No page available

10.1016/j.jalz.2009.04.917 Get It

P2‐172: Wild‐type mouse tau transgenic model: Halfway to a complete AD model
Adams, Stephanie J. , Innes, Amy, Randle, Suzanne J. , Yu, Cindy, Hutton, Mike, Dugger, Brittany N. , Crook, Richard , McGowan, Eileen , Dickson, Dennis W.

Alzheimer's & Dementia | July 24, 2008 | Volume: 4 | Issue: 4S_Part_12 | Pages: No page available

10.1016/j.jalz.2008.05.1246 Get It

P3–163: Identification of a novel risk gene for progressive supranuclear palsy by a genome–wide scan of 500,288 SNPs
Melquist, Stacey , Huentelman, Matthew J. , Craig, David W. , Baker, Matt , Zisman, Victoria L., Gass, Jennifer , Adamson, Jennifer, Szelinger, Szabolcs , Cournevaux, Jason J., Coon, Keith D., Stephan, Dietrich A. , Hutton, Michael , Crook, Richard , Pearson, John V. , Cannon, Ashley , Dickson, Dennis W.

Alzheimer's & Dementia | August 17, 2006 | Volume: 2 | Issue: 3S_Part_14 | Pages: No page available

10.1016/j.jalz.2006.05.1431 Get It

Susceptibility Locus for Alzheimer's Disease on Chromosome 10
Holmans, Peter , Marshall, Helen, Kwon, Jennifer M. , Meyer, David , Ramic, Dzanan, Shears, Shantia, DeVriéze, Fabienne Wavrant, Hamshere, Marian L. , Abraham, Richard, Tunstall, Nigel, Rice, Frances , Carty, Stephanie, Lillystone, Sara, Kehoe, Patrick G. , Rudrasingham, Varuni, Jones, Lesley , Lovestone, Simon , Pérez‐Tur, Jordi , Williams, Julie , Hardy, John , Goate, Alison , Myers, Amanda , Booth, Jeremy , Crook, Richard , Owen, Michael J. , Hardy, John , Goate, Alison M

Science | July 27, 2002 | Volume: 290 | Issue: 5500 | Pages: 2304-2305

10.1126/science.290.5500.2304 Get It

The apolipoprotein E ( APOE ) gene is the only genetic risk factor that has so far been linked to risk for late-onset Alzheimer's disease (LOAD). However, 50 percent of Alzheimer's disease cases do not carry an APOE4 allele, suggesting that other risk factors must exist. We performed a two-stage genome-wide screen in sibling pairs with LOAD to detect other susceptibility loci. Here we report evidence for an Alzheimer's disease locus on chromosome 10. Our stage one multipoint lod score (logarithm of the odds ratio for linkage/no linkage) of 2.48 (266 sibling pairs) increased to 3.83 in stage 2 (429 sibling pairs) close to D10S1225 (79 centimorgans). This locus modifies risk for Alzheimer's disease independent of APOE genotype.