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449 citation(s) found for "Ja, Fields".

Temporal onset of core features in Lewy body disease pathologic subtypes (2633)
Graff‐Radford, Jonathan , Aakre, Jeremiah A. , Wurtz, Lincoln , Graff‐Radford, Neill R. , Savica, Rodolfo , Fields, Julie A. , Pedraza, Otto , Reichard, Ross R., Petersen, Ronald C. , Choudhury, Parichita , Boeve, Bradley F. , Knopman, David S. , Kantarci, Kejal , Dickson, Dennis W. , Ferman, Tanis J.

Neurology | December 7, 2023 | Volume: 96 | Issue: 15_supplement | Pages: No page available

10.1212/wnl.96.15_supplement.2633 Get It

Clinical and Pathologic Features of Patients with REM Sleep Behavior Disorder and Parkinsonism in the Mild Cognitive Impairment Stage of Lewy Body Disease (859)
Miyagawa, Toji , Graff‐Radford, Neill R. , Knopman, David S. , Graff‐Radford, Jonathan , Savica, Rodolfo , Pedraza, Otto , Fields, Julie A. , Forsberg, Leah K. , Silber, Michael H. , Parisi, Joseph E., Petersen, Ronald C. , Ferman, Tanis J. , Knopman, David S. , Jones, David, Machulda, Mary M. , Allen, Laura, Kantarci, Kejal , Louis, Erik K. St. , Murray, Melissa E. , Dickson, Dennis W. , Boeve, Bradley F.

Neurology | December 7, 2023 | Volume: 94 | Issue: 15_supplement | Pages: No page available

10.1212/wnl.94.15_supplement.859 Get It

The ARTFL LEFFTDS Frontotemporal Lobar Degeneration (ALLFTD) Protocol: Preliminary Data and Future Plans (2081)
Boxer, Adam L. , Rosen, Howard, Forsberg, Leah K. , Heuer, Hilary W. , Brushaber, Danielle , Bordelon, Yvette , Dickerson, Bradford, Dickinson, Susan, Faber, Kelley , Fagan, Anne M. , Fields, Julie A. , Fishman, Ann, Gavrilova, Ralitza H. , Gendron, Tania, Geschwind, Daniel H. , Ghoshal, Nupur , Graff‐Radford, Jonathan , Graff‐Radford, Neill R. , Grant, Ian , Huey, Edward D. , Karydas, Anna, Kaufer, Daniel , Kramer, Joel H. , Kornak, John , Lagone, Emma, Ljubenkov, Peter A. , Lucente, Diane , Mackenzie, Ian R. , Manoochehri, Masood , Masdeu, Joseph C. , McGinnis, Scott, Mendez, Mario F. , Miller, Bruce, Miyagawa, Toji , Nelson, K. , Onyike, Chiadi U. , Pearlman, Rodney , Petrucelli, Leonard , Rademakers, Rosa , Ramos, Eliana Marisa , Rankin, Katherine P. , Rascovsky, Katya, Ritter, Aaron, -Martinez, Julio Rojas, Sabbagh, Marwan N. , Salmon, David P. , Savica, Rodolfo , Staffaroni, Adam M. , Syrjanen, Jeremy A. , Tatton, Nadine , Taylor, Joanne, Toga, Arthur W. , Weıntraub, Sandra , Wheaton, Diana, Boeve, Bradley F. , Appleby, Brian S. , Biernacka, Joanna M. , Botha, Hugo , Brannelly, Patrick , Dickson, Dennis W. , Domoto‐Reilly, Kimiko , Foroud, Tatiana , Galasko, Douglas , Gendron, Tania F. , Goldman, Jill , Grossman, Murray , Hsiung, Ging‐Yuek Robin , Huang, Eric J. , Irwin, David J. , Jones, David T. , Kantarci, Kejal , Knopman, David S. , Kremers, Walter K. , Kukull, Walter A. , Litvan, Irene , Masdeu, Joseph C , Nelson, Kevin, Pantelyat, Alexander , Pascual, Belén , Rexach, Jessica E. , Roberson, Erik D. , Seeley, William W. , Tartaglia, Maria Carmela , Wong, Bonnie , Wszołek, Zbigniew K.

Neurology | December 7, 2023 | Volume: 94 | Issue: 15_supplement | Pages: No page available

10.1212/wnl.94.15_supplement.2081 Get It

The Disease Severity Index for Inflammatory Bowel Disease Is a Valid Instrument that Predicts Complicated Disease
Swaminathan, Akhilesh , Fulforth, James , Frampton, Chris , Borichevsky, Grace M , Mules, Thomas , Kilpatrick, Kate, Choukour, Myriam, Fields, Peter A. , Ramkissoon, Resham­ , Helms, Emily G., Leong, Rupert W. , Mules, Thomas C , Siegel, Corey A , Leong, Rupert W , Kilpatrick, Kate, Fields, Peter, Hanauer, Stephen B. , Peyrin‐Biroulet, Laurent , Gearry, Richard B.

Inflammatory Bowel Diseases | December 5, 2023 | Volume: 30 | Issue: 11 | Pages: 2064-2075

10.1093/ibd/izad294 | PMID 38134391 Get It

Abstract Background The disease severity index (DSI) for inflammatory bowel disease (IBD) combines measures of disease phenotype, inflammatory activity, and patient-reported outcomes. We aimed to validate the DSI and assess its utility in predicting a complicated IBD course. Methods A multicenter cohort of adults with IBD was recruited. Intraclass correlation coefficients (ICCs) and weighted Kappa assessed inter-rater reliability. Cronbach’s alpha measured internal consistency of DSI items. Spearman’s rank correlations compared the DSI with endoscopic indices, symptom indices, quality of life, and disability. A subgroup was followed for 24 months to assess for a complicated IBD course. Area under the receiver operating characteristics curve (AUROC) and multivariable logistic regression assessed the utility of the DSI in predicting disease progression. Results Three hundred and sixty-nine participants were included (Crohn’s disease [CD], n = 230; female, n = 194; mean age, 46 years [SD, 15]; median disease duration, 11 years [interquartile range, 5-21]), of which 171 (CD, n = 99; ulcerative colitis [UC], n = 72) were followed prospectively. The DSI showed inter-rater reliability for CD (ICC 0.93, n = 65) and UC (ICC 0.97, n = 33). The DSI items demonstrated inter-rater agreement (Kappa > 0.4) and internal consistency (CD, α > 0.59; UC, α > 0.75). The DSI was significantly associated with endoscopic activity (CDn=141, r = 0.65, P < .001; UCn=105, r = 0.80, P < .001), symptoms (CDn=159, r = 0.69, P < .001; UCn=132, r = 0.58, P < .001), quality of life (CDn=198, r = −0.59, P < .001; UCn=128, r = −0.68, P < .001), and disability (CDn=83, r = −0.67, P < .001; UCn=52, r = −0.74, P < .001). A DSI of 23 best predicted a complicated IBD course (AUROC = 0.82, P < .001) and was associated with this end point on multivariable analyses (aOR, 9.20; 95% confidence interval, 3.32-25.49). Conclusions The DSI reliably encapsulates factors contributing to disease severity and accurately prognosticates the longitudinal IBD course.