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Allen, Mariet

https://orcid.org/0000-0002-2685-427X

Mayo Clinic

Mayo Clinic

Citations 130

IC‐P‐072: Gene Expression Of ABCA7 Dysregulated in Peripheral Blood is Associated With Decreased Metabolic Activity in Hippocampus
Kim, Sungeun , Horgousluoglu, Emrin, Apostolova, Liana G. , Lin, Kuang , Allen, Mariet , Wang, Xue , Ertekin‐Taner, Nilüfer , Petersen, Ronald , Soares, Holly , Singh, Parul , Wang, Lisu, Qi, Zhenhao, He, Aiqing, Neuhaus, Isaac , Patel, Vishal , Faber, Kelley, Simmons, Andrew , Weiner, Michael W. , Nho, Kwangsik T. , Risacher, Shannon L. , Keohane, Aoife , Lunnon, Katie , Hodges, Angela , Burgess, Jeremy D. , Foroud, Tatiana , Lovestone, Simon , Saykin, Andrew J.

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_1 | Pages: No page available

10.1016/j.jalz.2016.06.102 Get It

O2‐06‐02: Genome‐Wide Meta‐Analysis of Transcriptome Profiling Identifies Novel Dysregulated Genes Implicated in Alzheimer's Disease
Apostolova, Liana G. , Lin, Kuang, Allen, Mariet , Wang, Xue , Ertekin‐Taner, Nilüfer , Petersen, Ronald , Soares, Holly , Wang, Lisu, Qi, Zhenhao, He, Aiqing, Neuhaus, Isaac , Patel, Vishal , Faber, Kelley, Simmons, Andrew , Weiner, Michael W. , Nho, Kwangsik T. , Kim, Sungeun , Risacher, Shannon L. , Keohane, Aoife , Lunnon, Katie , Hodges, Angela , Burgess, Jeremy D. , Singh, Parul , Foroud, Tatiana , Lovestone, Simon , Saykin, Andrew J.

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_5 | Pages: No page available

10.1016/j.jalz.2016.06.425 Get It

P4‐031: Integrative Network Analysis of Multiple Alzheimer's Disease Rnaseq Studies From the Accelerating Medicine Partnership‐Alzheimer's Disease Consortium
Zhang, Bin , Komashko, Vitalina, Mostafavi, Sara , Funk, Cory C. , Allen, Mariet , Amberkar, Sandeep , Hide, Winston, Schadt, Eric , Jager, Philip L. De , Ertekin‐Taner, Nilüfer , Logsdon, Ben , Chen, Mingming , Perumal, Thanneer Malai , Hide, Winston, Friend, Stephen , Bennett, David A. , Price, Nathan D. , Mangravite, Lara M.

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_21 | Pages: No page available

10.1016/j.jalz.2016.06.2120 Get It

P3‐092: Mapping Regulatory Variants in the Alzheimer's Disease Candidate Gene ABCA7
Clement, Naomi , Medway, Christopher, Ertekin‐Taner, Nilüfer , Carrasquillo, Minerva M. , Younkin, Steven G. , Allen, Mariet , Tam, Tammie , Petersen, Ronald C. , Graff‐Radford, Neill R. , Carrasquillo, Minerva M. , Guetta‐Baranes, Tamar , Burgess, Jeremy D. , Dickson, Dennis W. , Chappell, Sally , Morgan, Kevin

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_17 | Pages: No page available

10.1016/j.jalz.2016.06.1751 Get It

P4‐027: Combing Evidence Across Multiple Cohorts for Systems‐Based Target Discovery: the AMP‐AD Knowledge Portal
Allen, Mariet , Funk, Corey, Xu, Jishu , Logsdon, Ben , Yu, Lei , Schuyler, Sarah, Friend, Stephen , Schadt, Eric , Jager, Philip L. De , Ertekin‐Taner, Nilüfer , Dang, Kristen K. , Perumal, Thanneer Malai , Wang, Minghui , Bennett, David A. , Zhang, Bin , Price, Nathan D. , Mangravite, Lara M.

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_21 | Pages: No page available

10.1016/j.jalz.2016.06.2116 Get It

MAPT haplotype H1G is associated with increased risk of dementia with Lewy bodies
Lorenzo‐Betancor, Oswaldo , Soto‐Ortolaza, Alexandra I., Walton, Ronald L., Murray, Melissa E. , Allen, Mariet , Uitti, Ryan J. , Smith, Glenn E. , Kantarci, Kejal , Lowe, Val J. , Jack, Clifford R. , Ertekin‐Taner, Nilüfer , Hassan, Anhar , Savica, Rodolfo , Petersen, Ronald C. , Parisi, Joseph E., Maraganore, Demetrius M. , Graff‐Radford, Neill R. , Ferman, Tanis J. , Ross, Owen A. , Soto‐Beasley, Alexandra I. , Labbé, Catherine, Lorenzo-Betancor, Oswaldo, Soto-Ortolaza, Alexandra I., Labbé, Catherine , Heckman, Michael G. , Wszołek, Zbigniew K. , Knopman, David S. , Boeve, Bradley F. , Dickson, Dennis W. , Jack, Clifford R , Ross, Owen A , Kantarci, Kejal , Murray, Melissa E , Ferman, Tanis J , Beasley, Alexandra I

Alzheimer's & Dementia | June 8, 2016 | Volume: 12 | Issue: 12 | Pages: 1297-1304

10.1016/j.jalz.2016.05.002 Get It

Abstract Introduction The MAPT H1 haplotype has been associated with several neurodegenerative diseases. We were interested in exploring the role of MAPT haplotypic variation in risk of dementia with Lewy bodies (DLB). Method We genotyped six MAPT haplotype tagging SNPs and screened 431 clinical DLB cases, 347 pathologically defined high‐likelihood DLB cases, and 1049 controls. Result We performed haplotypic association tests and detected an association with the protective H2 haplotype in our combined series (odds ratio [OR] = 0.75). We fine‐mapped the locus and identified a relatively rare haplotype, H1G, that is associated with an increased risk of DLB (OR = 3.30, P = .0017). This association was replicated in our pathologically defined series (OR = 2.26, P = .035). Discussion These results support a role for H1 and specifically H1G in susceptibility to DLB. However, the exact functional variant at the locus is still unknown, and additional studies are warranted to fully explain genetic risk of DLB at the MAPT locus.