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Carrasquillo, Minerva M.

https://orcid.org/0000-0002-3231-9134

Mayo Clinic

Jacksonville College

Citations 123

African American exome sequencing identifies potential risk variants at Alzheimer disease loci
N’Songo, Aurelie, Carrasquillo, Minerva M. , Wang, Xue , Burgess, Jeremy D. , Nguyen, Thuy , Asmann, Yan W. , Serie, Daniel, Younkin, Steven G., Allen, Mariet , Pedraza, Otto , Duara, Ranjan , Custo, María T. Greig, Ertekin‐Taner, Nilüfer , Serie, Daniel J, Greig Custo, Maria T, Carrasquillo, Minerva M. , Duara, Ranjan , Graff, Caroline

Neurology Genetics | April 8, 2017 | Volume: 3 | Issue: 2 | Pages: No page available

10.1212/nxg.0000000000000141 Get It

Comprehensive Screening for Disease Risk Variants in Early-Onset Alzheimer’s Disease Genes in African Americans Identifies Novel PSEN Variants
N’Songo, Aurelie, Carrasquillo, Minerva M. , Wang, Xue , Nguyen, Thuy , Asmann, Yan W. , Younkin, Steven G., Allen, Mariet , Duara, Ranjan , Custo, María T. Greig, Graff‐Radford, Neill R. , Ertekin‐Taner, Nilüfer , Asmann, Yan, Carrasquillo, Minerva M. , Duara, Ranjan

Journal of Alzheimer’s Disease | January 20, 2017 | Volume: 56 | Issue: 4 | Pages: 1215-1222

10.3233/jad-161185 Get It

We conducted a comprehensive screening of rare coding variants in an African American cohort to identify novel pathogenic mutations within the early-onset Alzheimer’s disease (EOAD) genes ( APP, PSEN1 , and PSEN2) in this understudied population. Whole-exome sequencing of 238 African American subjects identified 6 rare missense variants within the EOAD genes, which were observed in AD cases but never among controls. These variants were analyzed in an independent cohort of 300 African American subjects in which PSEN2 :NM_000447:exon5:c.T331C:p.Phe111Leu and PSEN1-minilin rs777923890 variants were again not observed, indicating that these novel rare variants, may contribute to AD risk in this population.
ABCA7 loss-of-function variants, expression, and neurologic disease risk
Allen, Mariet , Lincoln, Sarah, Corda, M, Carrasquillo, Minerva M. , Reddy, Joseph S. , Burgess, Jeremy D. , Nguyen, Thuy , Malphrus, Kimberly G., Petersen, Ronald C. , Graff‐Radford, Neill R. , Ertekin‐Taner, Nilüfer , Lincoln, Sarah J, Corda, Morgane, Watzlawik, Jens O. , Carrasquillo, Minerva M. , Dickson, Dennis W.

Neurology Genetics | January 6, 2017 | Volume: 3 | Issue: 1 | Pages: No page available

10.1212/nxg.0000000000000126 Get It

O2‐10‐04: A Regulatory Variant at the TREM Gene Cluster Associates with Decreased Alzheimer’s Disease Risk and Increased TREML1 and TREM2 Brain Gene Expression
Carrasquillo, Minerva M. , Allen, Mariet , Strickland, Samantha L. , Aryal, Shivani , Kachadoorian, Michaela, Medway, Christopher, Younkin, Curtis, Nair, Asha, Chanana, Pritha , Wang, Xue , Serie, Daniel, Nguyen, Thuy , Lincoln, Sarah, Malphrus, Kimberly G., Golde, Todd E. , Jager, Philip L. De , Asmann, Yan W. , Younkin, Steven G., Ertekin‐Taner, Nilüfer , Carrasquillo, Minerva M. , Burgess, Jeremy D. , Siuda, Joanna S. , Morgan, Kevin , Price, Nathan D. , White, Charles, Soni, Rajesh K , Crook, Julia E. , Dickson, Dennis W.

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_5 | Pages: No page available

10.1016/j.jalz.2016.06.451 Get It

P4‐048: Convergent Analysis of Endophenotypes in Progressive Supranuclear Palsy
Allen, Mariet , Wang, Xue , Younkin, Curtis, Serie, Daniel, Baheti, Saurabh , Nguyen, Thuy , Lincoln, Sarah, Malphrus, Kimberly G., Carrasquillo, Minerva M. , Zou, Fanggeng, Chai, High-Seng, Schellenberg, Gerard D. , Younkin, Steven G. , Ördög, Tamás , Asmann, Yan W. , Ertekin‐Taner, Nilüfer , Sun, Zhifu , Burgess, Jeremy D. , Kouri, Naomi , Carrasquillo, Minerva M. , Murray, Melissa E. , Crook, Julia E. , Dickson, Dennis W.

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_21 | Pages: No page available

10.1016/j.jalz.2016.06.2137 Get It

F2‐01‐04: From Systems Level Transcriptomics to new Immune Targets for Alzheimer’s Disease
Golde, Todd E. , Ertekin‐Taner, Nilüfer , Chakrabarty, Paramita , Allen, Mariet , Carrasquillo, Minerva M. , Younkin, Steven G. , Levites, Yona , Funk, Corey, Heavner, Benjamen D., Logsdon, Ben , Li, Hongdong , Younkin, Curtis, Petersen, Ronald C. , Ceballos‐Diaz, Carolina, Rosario, Awilda M., Adamson, Jeniffer, Giasson, Benoit I. , Graff‐Radford, Neill R. , Yachnis, Tony, Zou, Fanggeng, Eddy, James A. , Wang, Xue , Chai, High-Seng, Serie, Daniel, Nguyen, Thuy , Lincoln, Sarah, Malphrus, Kimberly G., Bisceglio, Gina, Asmann, Yan W. , Carrasquillo, Minerva M. , Dickson, Dennis W. , Price, Nathan D. , Mangravite, Lara M. , Li, Hong-Dong, Burgess, Jeremy D. , Cruz, Pedro E. , Crook, Julia E. , Wang, Chen , Ma, Li

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_4 | Pages: No page available

10.1016/j.jalz.2016.06.383 Get It

P1‐117: Blood Gene Expression Changes Implicated in Alzheimer’s Disease
Allen, Mariet , Wang, Xue , Nguyen, Thuy , Malphrus, Kimberly G., Serie, Daniel, Strickland, Samantha L. , Lincoln, Sarah, Carrasquillo, Minerva M. , Schellenberg, Gerard D. , Lowe, Val J. , Younkin, Steven G. , Asmann, Yan W. , Petersen, Ronald C. , Ertekin‐Taner, Nilüfer , Burgess, Jeremy D. , Nho, Kwangsik T. , Carrasquillo, Minerva M. , Crook, Julia E. , Knopman, David S. , Saykin, Andrew J. , Jack, Clifford R.

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_9 | Pages: No page available

10.1016/j.jalz.2016.06.865 Get It

P3‐092: Mapping Regulatory Variants in the Alzheimer's Disease Candidate Gene ABCA7
Clement, Naomi , Medway, Christopher, Ertekin‐Taner, Nilüfer , Carrasquillo, Minerva M. , Younkin, Steven G. , Allen, Mariet , Tam, Tammie , Petersen, Ronald C. , Graff‐Radford, Neill R. , Carrasquillo, Minerva M. , Guetta‐Baranes, Tamar , Burgess, Jeremy D. , Dickson, Dennis W. , Chappell, Sally , Morgan, Kevin

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_17 | Pages: No page available

10.1016/j.jalz.2016.06.1751 Get It

P2‐079: Assessment of The Known and Candidate Alzheimer's Disease Genes in African‐Americans
N’Songo, Aurelie, Carrasquillo, Minerva M. , Wang, Xue , Nguyen, Thuy , Asmann, Yan W. , Younkin, Steven G. , Graff‐Radford, Neill R. , Ertekin‐Taner, Nilüfer , Carrasquillo, Minerva M. , Burgess, Jeremy D.

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_13 | Pages: No page available

10.1016/j.jalz.2016.06.1284 Get It

P2‐025: Genetic and epigenetic influences on brain gene expression in psp
Allen, Mariet , Wang, Xue , Younkin, Curtis, Ballard, Travis, Serie, Daniel, Baheti, Saurabh , Carrasquillo, Minerva M. , Nguyen, Thuy , Malphrus, Kimberly G., Lincoln, Sarah, Zou, Fanggeng, Chai, High-Seng, Schellenberg, Gerard D. , Younkin, Steven G., Ördög, Tamás , Asmann, Yan W. , Taner, Nilüfer, Burgess, Jeremy D. , Wang, Chen , Sun, Zhifu , Carrasquillo, Minerva M. , Crook, Julia E. , Dickson, Dennis W.

Alzheimer's & Dementia | December 15, 2015 | Volume: 11 | Issue: 7S_Part_10 | Pages: No page available

10.1016/j.jalz.2015.06.561 Get It