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Veale, Thomas

https://orcid.org/0000-0003-3703-8451

Mayo Clinic

UCL Queen Square Institute of Neurology

Citations 7

IC‐P‐165: ROBUST IDENTIFICATION OF BRAIN STRUCTURES MOST DISCRIMINATIVE IN DETECTING EARLY CHANGES IN AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE
Veale, Thomas , Altmann, André , Network, Dominantly Inherited Alzheimer, Molteni, Erika , Cardoso, M. Jorge , Benzinger, Tammie L.S. , Jack, Clifford R. , McDade, Eric , Morris, John C. , Rossor, Martin N. , Ourselin, Sébastien , Fox, Nick C. , Cash, David M. , Modat, Marc , Network, Dominantly Inherited Alzheimer

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_2 | Pages: No page available

10.1016/j.jalz.2018.06.2232 Get It

IC‐P‐048: SAMPLE SIZE ESTIMATES FOR SECONDARY PREVENTION STUDIES USING REGIONAL ATROPHY RATES
Veale, Thomas , Poole, Teresa, Network, Dominantly Inherited Alzheimer, Cash, David M. , Modat, Marc , Molteni, Erika , Cardoso, M. Jorge , Benzinger, Tammie L.S. , Jack, Clifford R. , McDade, Eric , Bateman, Randall J. , Morris, John C. , Rossor, Martin N. , Ourselin, Sébastien , Frost, Chris , Fox, Nick C. , Network, Dominantly Inherited Alzheimer

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_1 | Pages: No page available

10.1016/j.jalz.2018.06.2112 Get It

P2‐438: ROBUST IDENTIFICATION OF BRAIN STRUCTURES MOST DISCRIMINATIVE IN DETECTING EARLY CHANGES IN AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE
Veale, Thomas , Altmann, André , (DIAN), Dominantly Inherited Alzheimer Network, Molteni, Erika , Cardoso, M. Jorge , Benzinger, Tammie L.S. , Jack, Clifford R. , McDade, Eric , Morris, John C. , Rossor, Martin N. , Ourselin, Sébastien , Fox, Nick C. , Cash, David M. , Modat, Marc , (DIAN), Dominantly Inherited Alzheimer Network

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_16 | Pages: No page available

10.1016/j.jalz.2018.06.1130 Get It

P1‐410: SAMPLE SIZE ESTIMATES FOR SECONDARY PREVENTION STUDIES USING REGIONAL ATROPHY RATES
Veale, Thomas , Poole, Teresa, (DIAN), Dominantly Inherited Alzheimer Network, Cash, David M. , Modat, Marc , Molteni, Erika , Cardoso, M. Jorge , Benzinger, Tammie L.S. , Jack, Clifford R. , McDade, Eric , Bateman, Randall J. , Morris, John C. , Rossor, Martin N. , Ourselin, Sébastien , Frost, Chris , Fox, Nick C. , (DIAN), Dominantly Inherited Alzheimer Network

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_8 | Pages: No page available

10.1016/j.jalz.2018.06.419 Get It

Utility of perfusion PET measures to assess neuronal injury in Alzheimer's disease
Joseph‐Mathurin, Nelly , Jasielec, Mateusz S., Vlassenko, Andrei G. , Gordon, Brian A. , Hornbeck, Russ C. , Cash, Lisa, Veale, Thomas , Cash, David M. , Buckles, Virginia, Cairns, Nigel J. , Goate, Alison , Karch, Celeste M. , Klunk, William E. , Marcus, Daniel S. , Mayeux, Richard , Noble, James M. , Ringman, John M. , Xiong, Chengjie , Morris, John C. , Bateman, Randall J. , Network, Dominantly Inherited Alzheimer, Gordon, Brian A , Bateman, Randall J , Joseph-Mathurin, Nelly , Karch, Celeste M , Morris, John C , Cash, David M , Su, Yi , Blazey, Tyler , Friedrichsen, Karl A. , Ances, Beau M. , Brickman, Adam M. , Cruchaga, Carlos , Jack, Clifford R. , Koeppe, Robert A. , McDade, Eric , Saykin, Andrew J. , Thompson, Paul M. , Benzinger, Tammie L.S. , Network, Dominantly Inherited Alzheimer, Goate, Alison M , Noble, James M

Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring | September 27, 2018 | Volume: 10 | Issue: 1 | Pages: 669-677

10.1016/j.dadm.2018.08.012 Get It

AbstractIntroduction18F‐fluorodeoxyglucose (FDG) positron emission tomography (PET) is commonly used to estimate neuronal injury in Alzheimer's disease (AD). Here, we evaluate the utility of dynamic PET measures of perfusion using 11C‐Pittsburgh compound B (PiB) to estimate neuronal injury in comparison to FDG PET.MethodsFDG, early frames of PiB images, and relative PiB delivery rate constants (PiB‐R1) were obtained from 110 participants from the Dominantly Inherited Alzheimer Network. Voxelwise, regional cross‐sectional, and longitudinal analyses were done to evaluate the correlation between images and estimate the relationship of the imaging biomarkers with estimated time to disease progression based on family history.ResultsMetabolism and perfusion images were spatially correlated. Regional PiB‐R1 values and FDG, but not early frames of PiB images, significantly decreased in the mutation carriers with estimated year to onset and with increasing dementia severity.DiscussionHypometabolism estimated by PiB‐R1 may provide a measure of brain perfusion without increasing radiation exposure.
[IC‐P‐150]: CHARACTERISING PRESYMPTOMATIC ATROPHY PATTERNS THROUGH MULTIVARIATE MACHINE LEARNING
Veale, Thomas , (DIAN), the Dominantly Inherited Alzheimer Network, Wallon, David , Ridgway, Gerard R. , Benzinger, Tammie L.S. , Jack, Clifford R. , Bateman, Randall J. , Morris, John C. , Weston, Philip S.J. , Rossor, Martin N. , Ourselin, Sébastien , Modat, Marc , Fox, Nick C. , Cash, David M. , (DIAN), the Dominantly Inherited Alzheimer Network

Alzheimer's & Dementia | October 20, 2017 | Volume: 13 | Issue: 7S_Part_2 | Pages: No page available

10.1016/j.jalz.2017.06.2424 Get It

[O1–02–02]: CHARACTERISING PRESYMPTOMATIC ATROPHY PATTERNS THROUGH MULTIVARIATE MACHINE LEARNING
Veale, Thomas , Weston, Philip SJ., (DIAN), The Dominantly Inherited Alzheimer Network, Wallon, David , Ridgway, Gerard R. , Benzinger, Tammie L.S. , Jack, Clifford R. , Bateman, Randall J. , Morris, John C. , Weston, Philip S.J. , Rossor, Martin N. , Ourselin, Sébastien , Modat, Marc , Fox, Nick C. , Cash, David M. , (DIAN), The Dominantly Inherited Alzheimer Network

Alzheimer's & Dementia | October 20, 2017 | Volume: 13 | Issue: 7S_Part_3 | Pages: No page available

10.1016/j.jalz.2017.07.040 Get It