Citations 3
Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS)
Investigators, The Huntington Study Group PHAROS, Biglan, Kevin , Shoulson, Ira , Kieburtz, Karl , Oakes, David , Kayson, Elise, Shinaman, M. Aileen, Zhao, Hongwei , Romer, Megan, Young, Anne B., Hersch, Steven M. , Penney, Jack, Marder, Karen, Paulsen, Jane S. , Quaid, Kimberly A., Siemers, Eric , Mallonee, William, Suter, Greg, Dubinsky, Richard , Nance, Martha , Bundlie, Scott R., Radtke, Dawn, Kostyk, Sandra K. , Baic, Corrine, Walker, Francis O. , Hunt, Victoria, Chouinard, Sylvain, Wood‐Siverio, Cathy, Corey‐Bloom, Jody , Peavy, Guerry M. , Moskowitz, Carol, Wesson, Melissa, Samii, Ali, Bird, Thomas D. , Lipe, Hillary, Blindauer, Karen, Marshall, Frederick J., Zimmerman, Carol, Goldstein, Jody, Rosas, Diana, Novák, Péter , Caviness, John N., Duffy, Amy, Wheelock, Vicki, Tempkin, Teresa, Seeberger, Lauren , Albin, Roger L. , Racette, Brad A. , Perlman, Susan , Bordelon, Yvette , Martin, W. R. Wayne , Wieler, Marguerite , Raymond, Lynn A. , Decolongon, Joji, Hunter, Christine , Hauser, Robert A. , Furtado, Sarah , Suchowersky, Oksana , Klimek, Mary Lou, Guttman, Mark, Sethna, Rustom, Feigin, Andrew, Cox, Marie, Shannon, Barbara , Percy, Alan K. , Dure, Leon , Harrison, Madaline B. , Higgins, Donald S. , Molho, Eric , Nickerson, Constance, Evans, Sharon, Hobson, Douglas, Singer, Carlos , Gálvez-Jiménez, Néstor, Shannon, Kathleen M. , Comella, Cynthia , Ross, Christopher A. , Hogarth, Penelope , Weiner, William J., Como, Peter G., Kumar, Rajeev , Cotto, Candace, Stout, Julie C. , Brocht, Alicia, Watts, Arthur, Eberly, Shirley , Weaver, Christine , Gusella, James F. , MacDonald, Marcy E., Fahn, Stanley, Shults, Clifford W., Caviness, John, Investigators, The Huntington Study Group PHAROS, Tanner, Caroline M. , Gray, Carolyn Steele , Baic, Corrine L., Caress, James B. , O’Neill, Christine J. , Factor, Stewart Alan , Greenamyre, J. Timothy , Song, David , Adler, Charles H. , Richman, David P. , Chou, Kelvin L. , Perlmutter, Joel S. , Leavitt, Blair R. , Clarke, Lorne A. , Jankovic, Joseph J. , Sanchez‐Ramos, Juan , Johnson, William , Saint‐Hilaire, Marie , Testa, Claudia M. , Rosenblatt, Adam E , Foroud, Tatiana , Myers, Richard H. , Ross, Christopher A , Hauser, Robert A
JAMA Neurology | November 16, 2015 | Volume: 73 | Issue: 1 | Pages: 102
CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion
Lee, J.-M., Ramos, E.M., Lee, J.-H., Gillis, Tammy , Mysore, Jayalakshmi Srinidhi, Hayden, Michael R. , Warby, Simon C. , Morrison, PJ, Nance, Martha , Ross, Christopher A. , Margolis, Russell L. , Squitieri, Ferdinando , Orobello, S., Donato, Stefano Di , Gómez‐Tortosa, Estrella , Ayuso, Carmen , Suchowersky, Oksana , Trent, R J, McCusker, Elizabeth, Novelletto, Andrea , Frontali, Marina , Jones, Randi, Ashizawa, Tetsuo , Saint‐Hilaire, Marie , Hersch, Steven M. , Rosas, H. Diana , Lucente, Diane , Harrison, Madeline, Zanko, Andrea, Abramson, Ruth K., Marder, Karen, Sequeiros, Jorge , Paulsen, Jane S. , Landwehrmeyer, G. Bernhard , Myers, Richard H. , MacDonald, Marcy E., Gusella, James F. , Frati, Luigi, Perlman, Susan B. , Conneally, P. M., Klimek, Mary Lou, Diggin, Melissa, Hadzi, Tiffany C., Duckett, Ayana, Ames, David, Anderson, Christine, Anderson, Karla J., Anderson, Karen, Andrews, Thomasin, Axelson, Eric, Aylward, Elizabeth , Barker, Roger A. , Barth, Katrin, Barton, Stacey K. , Baynes, Kathleen, Bea, Alexandra, Beglinger, Leigh J., Biglan, Kevin , Björk, K., Blanchard, Steve, Bockholt, Jeremy , Bommu, Sudharshan Reddy, Brossman, Bradley G., Burrows, Maggie, Calhoun, Vince D. , Carlozzi, Noelle E. , Chesire, Amy M., Chiu, Edmond, Connell, R.J., Connor, Carmela, Corey‐Bloom, Jody , Craufurd, David, Cross, Stephen, Santos, Rachelle Dar, Davis, Jennifer , Decolongon, Joji, Dipietro, A., Doucette, Nicholas, Downing, Nancy R. , Dudler, Ann, Ecker, Daniel, Erickson, Diane, Erwin, Cheryl , Farias, Sarah Tomaszewski , Fatas, Marta, Fullam, Ruth, Furtado, Sarah , Garde, Mónica Bascuñana, Geschwind, Michael D., Gooblar, Jon, Goodman, Anna , Griffith, Jane, Groves, Mark, Guttman, Mark, Hamilton, Joanne M., Harris, Greg, Heaton, Robert K. , Helmer, Karl, Henneberry, Machelle, Herwig, Kelly, Howard, Elizabeth, Hunter, Christine , Jankovic, Joseph, Johnson, Hans J. , Johnson, Arik, Jones, Kathy, Kimble, Mycah, King, Pamela, Klöppel, Stefan , Komiti, Angela , Kumar, Rajeev , Leavitt, Blair, Leserman, Anne, Lipe, Hillary, Lowe, Mark J. , Magnotta, Vincent A. , Mallonee, William, Mans, Nicole , Marietta, Jacquie, Marshall, Frederick J., Mason, Sarah, Matheson, Kirsty, Matson, Wayne R., McDowell, William , Miedzybrodzka, Zosia , Mills, James A. , Miracle, Dawn, Montross, Kelsey, Moore, David D. , Mori, S., Moskowitz, Carol, Newman, Emily R., Novak, Marianne, O’Rourke, Justin J. F., Oakes, David , Ondo, William G. , Orth, Michael, Pease, Karen R., Perlmutter, Joel, Peterson, Asa , Pierson, Ron, Preston, J. Samuel, Quaid, Kimberly A., Radtke, Dawn, Rae, D. O., Raymond, Lynn A. , Reading, Sarah, Ready, Rebecca E. , Reece, Christine, Reynolds, Norm, Richardson, Kylie, Rickards, Hugh , Ro, Eunyoe , Rodnitzky, Robert L., Rosser, Elisabeth, Rosser, Anne, Price, Kathy, Price, Kathy, Ryan, Pat, Salmon, David P. , Samii, Ali, Schumacher, Jamy, Sendon, Jose Luis Lópenz, Shear, Paula K. , Sheinberg, Alanna, Shpritz, Barnett, Simpson, Sheila A., Singer, Adam D. , Smith, Megan M. , Snyder, Pete, Song, Allen W. , Sran, Satwinder, Stober, Janice, muth, Sigurd Sü, Suter, Greg, Tabrizi, Sarah J. , Tempkin, Terry, Thompson, Sean , Thomsen, Teri, Thumma, Kelli, Trautmann, Sonja, Tremont, Geoff, Turner, Jessica A. , Uc, Ergun, Duijn, E. van, Walsem, Marleen van, Vik, Stacie , Vonsattel, Jean Paul, Vuletich, Elizabeth J., Warner, Tom, Wasserman, Paula, Waterman, Elijah, Weaver, Kurt E. , Weir, David , Werling-Witkoske, Chris, Wesson, Melissa, Westervelt, Holly James , Weydt, Patrick , Wheelock, Vicki, Wodarski, Mary, Wojcieszek, Joanne, Wood, Jessica, Wood‐Siverio, Cathy, Wu, Shuhua , Yastrubetskaya, Olga, Yébenes, Justo García de, Zhao, Yong Qiang, Zimbelman, Janice L., Zschiegner, Roland, Aaserud, Olaf, Abbruzzese, Giovanni , Andrews, Thomasin, Andrich, Jurgin, Antczak, Jakub , Arran, Natalie, Artiga, María José Saiz, Bachoud‐Lévi, Anne‐Catherine , Banaszkiewicz, Krysztof, Barberá, Miguel Aguilar, Barrero, Francisco Javier , Bas, Jordi, Beister, Antoine, Bertini, Elisabetta, Biunno, Ida , Bjørgo, Kathrine, Bjørnevoll, Inga, Bohlen, Stefan, Bonelli, Raphael M., Bos, Reineke, Bourne, Colin, Bradbury, Alyson, Brockie, Peter, Brown, Felicity, Buck, Andrea, Burg, Sabrina, Burgunder, Jean‐Marc , Burns, Peter, Burrows, Liz, Calopa, Matilde , Carruesco, Gemma Tome, Casado, Ana Gonzalez, Catena, Judit López, Chu, Carol , Clapton, Jackie, Clayton, Carole, Clenaghan, Catherine, Connemann, Julia, Crooks, Jenny, Cubillo, Patricia Trigo, Cubo, Esther , Curtis, Adrienne, Michele, Giuseppe De , Souza, Jenny de, Weert, A. Marit de, Dekker, M., Descals, Asunción Martínez, Maio, Luigi Di, Pietro, Anna Di, Dipple, Heather, Dose, M., Dumas, Eve M., Dunnett, Stephen B. , Elifani, Francesca , Ellison-Rose, Lynda, Elorza, Marina D., Eschenbach, Carolin, Evans, Carole, Fairtlough, Helen, Fannemel, Madelein, Fenollar, María del Mar, Ferrandes, Giovanna, Ferreira, Jaoquim J., Fillingham, Kay, Finisterra, Ana Maria, Fisher, Kate , Fletcher, Amy, Foster, Jillian, Foustanos, Isabella, Frech, Fernando Alonso, Fullam, Robert, Fullham, Ruth, Gago, Miguel , García, R. de Francisco, García, Socorro S., Garrett, Carolina, Gellera, Cinzia , Gill, Paul R., Ginestroni, Andrea, Golding, Charlotte, Gørvell, Per F., Griguoli, Anna Maria, Gross, Diana, BascuñanaGuerra, Monica, Guerra, Maria Rosália, Guerrero, Rosa , Guía, D. Badenes, Guidubaldi, Arianna, Hallam, Caroline, Hamer, Stephanie, Hammer, K., Handley, Olivia, Harding, Alison, Hasholt, Lis, Hedge, R.M., Heiberg, Arvid, Heinicke, Walburgis, Held, Christine, Hernanz, Laura Casas, Herranhof, Briggitte, Hiivola, Heli, Hjermind, Lena E. , Hobson, Emma, Hoffmann, Rainer , Holl, Anna, Howard, Liz Livingston, Huson, Susan, Ialongo, Tàmara, Idiago, Jesús Miguel Ruiz, Illmann, Torsten, Jachińska, Katarzyna, Jacopini, Gioia, Jakobsen, Oda, Jamieson, Stuart W., Jamrozik, Zygmunt , Janik, Piotr , Johns, Nicola, Jones, Lesley , Jones, Una , Jurgens, Caroline K., Kaelin‐Lang, Alain , Kershaw, Ann, Kieni, Janina, Koivisto, Susana Pro, Koppers, Kerstin, Kosinski, Christoph M., Kremer, Berry, Krysa, Wioletta, Kwieciński, Hubert, Lahiri, Nayana , Lambeck, Johann , Lange, Herwig W. , Laver, Fiona, Levey, Jamie, Leythaeuser, Gabriele, Lezius, Franziska , Llesoy, Joan Roig, Löhle, Matthias , López, Cristobal Diez-Aja, Lorenza, Fortuna, Loria, G, Magnet, Markus, Mandich, Paola , Mariotti, Caterina , Mariscal, Natividad, Marková, Ivana S. , Marquard, Ralf, Martikainen, Kirsti, Martínez, Isabel Haro, Martínez‐Descals, Asunción, Martino, T., Mason, Sarah, McKenzie, Sue, Mechi, Claudia, Middleton, Julia, Milkereit, Eva, Miller, Julie, Minster, Sara, Möller, Jens Carsten , Monza, Daniela, Morales, Blas, Moreau, Laura V., Murch, Ann, Niess, Anke, Nørremølle, Anne , O'Donovan, Kristy, Orth, Michael, Otti, Daniela, Padieu, Hélène, Paganini, M. , Painold, Annamaria , Päivärinta, Markku, Partington-Jones, Lucy, Paterski, Laurent, Paterson, Nicole D., Patino, Dawn Freire-, Patton, Michael J. , Peinemann, Alexander, Peppa, Nadia , Perea, María Fuensanta Noguera, Peterson, Maria, Càrdenas, Regina Pons i, Prehn, Christian, Price, Kathleen, Probst, Daniela, Quiroga, Purificacion Pin, Raab, Tina, Rakowicz, Maryla, Raman, Ashok, Raymond, Lucy, Reinante, Gema, Retterstøl, Lars, Ribaı̈, Pascale, Riballo, Antonio Villa, Ribas, Guillermo García, Rinaldi, Carlo , Rissling, Ida, Rivera, Susana Vázquez , Robert, Misericordia Floriach, Roca, Elvira, Romano, Silvia , Romoli, Anna Maria , Roos, Raymond A.C., Røren, Niini, Rosser, Anne, Rossi, F., Rothery, Jean, Ruíz, Belan Garzon, Russo, Cinzia Valeria , Ryglewicz, Danuta , Saft, Carston, Sánchez, Vicenta , Sando, Sigrid Botne , Šašinková, Pavla, Saß, Christian, Scheibl, Monika, Schiefer, Johannes, Schlangen, Christiane, Schöggl, Helmut, Schrenk, Caroline, Schüpbach, Michaël , Schuierer, Michele, Sebastián, Ana Rojo, Selimbegovic-Turkovic, Amina, Sempołowicz, Justyna, Silva, Mark, Sławek, Jarosław , Snowden, Julie S. , Soleti, Francesco, Sollom, Andrea, Sołtan, Witold, Sorbi, Sandro , Sørensen, Sven Asger, Spadaro, M., Städtler, Michael, Stamm, Christiane, Steiner, Tanja, Stokholm, Jette, Stokke, Bodil, Storch, Alexander , Straßburger, Katrin, Stubbe, Lars, Szczudlik, Andrzej, Taylor, Rachel , Terol, Santiago Duran-Sindreu, Thomas, Gareth, Thomson, Aileen, Tidswell, Katherine, Torres, María Martirio Antequera, Toscano, Jean, Townhill, Jenny, Tucci, Tecla, Tuuha, Katri, Uhrová, Tereza , Valadas, Anabela , Hout, Monique S.E. van, Oostrom, Joost C.H. van, Vugt, Jeroen P.P. van, vanm, Walsem Marleen R., Vandenberghe, Wim , Verellen‐Dumoulin, Christine, Vergara, M, Verstappen, C.C.P., Verstraelen, Nichola , Viladrich, Cèlia Mareca, Villanueva, Clara , Wahlström, Jan , Wehus, R., Weindl, A., Westmoreland, Leann, Wiedemann, Alexandra, Wild, Edward J. , Wild, Sue, Witjes‐Ané, Marie‐Noëlle W. , Witkowski, Grzegorz , Wójcik-Pędziwiatr, Magdalena , Wolz, Martin , Wolz, Annett, Wright, Jan, Yardumian, Pam, Yates, Shona, Yudina, Elizaveta, Zaugg, Sabine Weber, Zdzienicka, Elżbieta, Zielonka, Euginiusz, Zinzi, Paola , Zucker, B., Adams, John , Antonijevic, Irina , Beck, Christopher A. , Chiu, Edmond, Churchyard, Andrew, Colcher, Amy, Dorsey, Ray, Drazinic, Carolyn, Dubinsky, Richard , Duff, Kevin, Giuliano, Joe, Greenamyre, Timothy, Jennings, Dana, Kang, Un Jung , Kumar, Rajeev, Leavitt, Blair, LeDoux, Mark S. , Mohlo, Eric, Morgan, John C. , Panisset, Michel , Perlmutter, Joel, Revilla, Fredy J., Robertson, Suzanne, Robottom, B., Scott, B.L. , Shoulson, Ira , Singer, Carlos , Tabbal, Samer D., van, Kammen Dan, Vetter, Louise, Walker, Francis O. , Warner, John Harley , Weiner, illiam, Broyles, Janice, Clouse, Ronda, Coleman, Allison, Davis, Robert E. , de-la-Rosa, J.-L., Deuel, Lisa M., Dietrich, Susan, Dubinsky, Hilary, Eaton, Ken, Erickson, Diane, Fitzpatrick, Mary Jane, Frucht, Steven J. , Gartner, Maureen, Goldstein, Jody, Hickey, Charlyne, Hunt, Victoria, Jaglin, Jeana, Lindsay, Pat, Louis, Elan D. , Loy, Clemet, Lucarelli, N., Malarick, Keith, Martin, Amanda, McInnis, Robert , Nucifora, Frederick C. , Palao, Alicia, Peavy, Guerry M. , Quesada, Mónica, Schmidt, Amy P., Segro, Vicki, Sperin, Elaine, Tanev, Kalo, Tempkin, Teresa, Thiede, Curtis, Zauber, Elizabeth, Ferreira, Joaquim J. , Vivancos, L. , Frank, Samuel , Dürr, Alexandra , Rosenblatt, Adam E , Ahmed, Anwar E. , Allen, Paul D. , Anderson, Christine, Ashburner, John , Beall, Erik B. , Beg, Mirza Faisal , Calhoun, Vince D. , Chua, Phyllis M-L. , Cysique, Lucette A. , Dunn, Steve , Epping, Eric A. , Evans, Kenneth , Factor, Stewart Alan , Fiedorowicz, Jess G. , Gehl, Carissa , Goh, Anita , Gooblar, Jonathan, Harrington, Deborah Lynn , Hershey, Tamara G. , Jankovic, Joseph, Johnson, Arik, Juhl, Andrew R. , Kim, Eun Young , Koenig, Katherine A. , Langbehn, Douglas R. , Leavitt, Blair, Lim, Kelvin O. , Martin, W. R. Wayne , Mason, Sarah, Mazzoni, Pietro , Miller, Michael I. , Moser, David J. , Nopoulos, Peg , Orth, Michael, Panegyres, Peter K. , Perlmutter, Joel, Phillips, Michael , Potkin, Steven G. , Rao, Stephen M. , Reilmann, Ralf , Robinson, Robert A. , Rogers, Benedict D. , Rosser, Anne, Price, Kathy, Price, Kathy, Schumacher, Jessica R. , Siedlecki, Karen L. , Smith, Jim Q. , Smith, Glenn E. , Stephan, Klaas Enno , Testa, Claudia M. , Toga, Arthur W. , Uc, Ergun, Vaccarino, Anthony L. , Warner, Tom, Wassink, Thomas H. , Welsh, Claire E. , Williams, Kent C. , Williams, Janet K. , Wood, Jessica, Andrews, Thomasin, Poggio, M. , Bandmann, Oliver , Bentivoglio, Anna Rita , Bruno, Stefania , Bryl, Anna , Busquets, Núria , Busse, Monica E , Ciesielska, Anna , Coelho, Miguel M , Nicola, Antonio De , Fannemel, Madeleine , Fasano, Alfonso , Grant, Janet F. , Guedes, Leonor Correia , Herranhof, Brigitte, Herrera-Espiñeira, Carmen , Hidding, Ute , Hill, Susan , Hunt, Sarah E , Kalbarczyk, Anna , Khalil, Hanan W. , Klimberg, Aneta , Krawczyk, Małgorzata Anna , Kremer, Berry P. H., Leenders, Klaus Leonhard , Marchese, Roberta , Marcinkowski, T , Mason, Sarah, Mendes, Tiago , Mestre, Tiago , Miller, J. Philip , Moreau, Laura V., López-Sendón, José Luis , Münchau, Alexander Maximilian , Nielsen, Jørgen Erik , Orth, Michael, Owen, Michael J. , Freire-Patino, Dawn, Piacentini, Silvia , Piano, Carla , Quarrell, Oliver , Rakowicz, Maryla, Reisinger, Karin M. , Richter, Sven , Ritchie, Stuart James , Rose, Sarah , Rosser, Anne, Rudzińska, Monika , Ruiz, Pedro , Saft, Carston, Salvatore, Elena , Schmidt, Simone Bianca , Sitek, Emilia J. , Soliveri, Paola , Stopford, Cheryl L. , Sułek, Anna , Thompson, J. C. , Warner, Thomas T. , Werner, Cornelius Johannes , Zaremba, Jacek , Zielonka, Daniel , Zittel, Simone , Agarwal, Pinky , Chiu, Edmond, Duff, Kevin, Foroud, Tatiana , Greenamyre, Timothy, Higgins, Donald S. , Kostyk, Sandra K. , Kumar, Rajeev, Leavitt, Blair, Perlmutter, Joel, Sanchez‐Ramos, Juan , Shannon, Kathleen M. , Erickson, Diane, Muratori, Lisa M. , O’Neill, Christine J. , Turner, Jessica A , Ross, Christopher A , Ferreira, Joaquim J , Sławek, Jarosław , Magnotta, Vincent A
Neurology | February 9, 2012 | Volume: 78 | Issue: 10 | Pages: 690-695
Role of biomarkers in studies of presymptomatic Alzheimer's disease
Morris, John C. , Kimberly, A., Quaid, Kimberly A., Kantarci, Kejal , Kaye, Jeffrey , Reiman, Eric M. , Klunk, William E. , Siemers, Eric , Kimberly, A., Holtzman, David M. , Kantarci, Kejal , Morris, John C
Alzheimer's & Dementia | December 19, 2005 | Volume: 1 | Issue: 2 | Pages: 145-151
BackgroundBiomarkers that have been developed largely for the study of patients with clinically diagnosed Alzheimer's disease (AD) can also be used in the study of cognitively normal individuals who may harbor underlying AD pathology.MethodsA meeting of invited experts on AD biomarkers was held on November 11 and 12, 2004 to review currently available data and to discuss unmet needs for biomarker research in presymptomatic AD.ResultsNeuroimaging biomarkers have been studied to some extent in subjects at risk for AD. These imaging techniques include volumetric magnetic resonance imaging and positron emission tomography using either fluorodeoxyglucose or newer ligands that bind directly to amyloid plaque. Similarly, biochemical measures from cerebrospinal fluid or other physiologic fluids are emerging as potentially useful tools. Such biomarkers may be used either as diagnostic tools or as indicators of disease severity when followed longitudinally. A clinical diagnosis of asymptomatic individuals using biomarkers and studies involving asymptomatic subjects may raise logistical and ethical concerns.ConclusionsThe technical development of biomarkers that are used for presymptomatic AD diagnosis and for longitudinally measuring disease severity is evolving rapidly. Ethical and privacy considerations must be made before such biomarkers can be applied routinely to asymptomatic populations.