Back to Authors

Jagust, William J.

https://orcid.org/0000-0002-4458-113X

Mayo Clinic

University of California, Berkeley

Citations 125

The Alzheimer's Disease Neuroimaging Initiative 3: Continued innovation for clinical trial improvement
Weiner, Michael W. , Veitch, Dallas P. , Aisen, Paul , Cairns, Nigel J. , Harvey, Danielle, Jack, Clifford R. , Jagust, William J. , Morris, John C. , Petersen, Ronald C. , Salazar, Jennifer, Saykin, Andrew J. , Shaw, Leslie M. , Trojanowski, John Q. , Initiative, Alzheimer's Disease Neuroimaging, Harvey, Danielle , Beckett, Laurel , Green, Robert C. , Harvey, Danielle, Toga, Arthur W. , Initiative, Alzheimer's Disease Neuroimaging, Jack, Clifford R , Saykin, Andrew J , Morris, John C , Harvey, Danielle J

Alzheimer's & Dementia | December 5, 2016 | Volume: 13 | Issue: 5 | Pages: 561-571

10.1016/j.jalz.2016.10.006 Get It

Abstract Introduction The overall goal of the Alzheimer's Disease Neuroimaging Initiative (ADNI) is to validate biomarkers for Alzheimer's disease (AD) clinical trials. ADNI‐3, which began on August 1, 2016, is a 5‐year renewal of the current ADNI‐2 study. Methods ADNI‐3 will follow current and additional subjects with normal cognition, mild cognitive impairment, and AD using innovative technologies such as tau imaging, magnetic resonance imaging sequences for connectivity analyses, and a highly automated immunoassay platform and mass spectroscopy approach for cerebrospinal fluid biomarker analysis. A Systems Biology/pathway approach will be used to identify genetic factors for subject selection/enrichment. Amyloid positron emission tomography scanning will be standardized using the Centiloid method. The Brain Health Registry will help recruit subjects and monitor subject cognition. Results Multimodal analyses will provide insight into AD pathophysiology and disease progression. Discussion ADNI‐3 will aim to inform AD treatment trials and facilitate development of AD disease‐modifying treatments.
IC‐P‐205: Relationship Between [18F]Av‐1451 Binding and Antecedent Amyloid Deposition, Glucose Hypometabolism and Atrophy Measures: Preliminary Analysis in the ADNI Cohort
Deters, Kacie, Schwarz, Adam J. , Shcherbinin, Sergey, West, John D. , Jagust, William J. , Weiner, Michael W. , Saykin, Andy J., Initiative, Alzheimer's Disease Neuroimaging, Risacher, Shannon L. , Jack, Clifford R. , Saykin, Andy J., Initiative, Alzheimer's Disease Neuroimaging

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_3 | Pages: No page available

10.1016/j.jalz.2016.06.237 Get It

IC‐P‐207: Association of [18F]Av‐1451 TAU Markers with Cognitive and Neurodegeneration Measures: Preliminary Analysis in the ADNI Cohort
Deters, Kacie, Schwarz, Adam J. , Shcherbinin, Sergey, Jagust, William J. , Weiner, Michael W. , Saykin, Andy J., Initiative, Alzheimer's Disease Neuroimaging, Risacher, Shannon L. , Jack, Clifford R. , Saykin, Andy J., Initiative, Alzheimer's Disease Neuroimaging

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_3 | Pages: No page available

10.1016/j.jalz.2016.06.239 Get It

O3‐02‐02: Relationship Between [18F]AV‐1451 Binding and Antecedent Amyloid Deposition, Glucose Hypometabolism and Atrophy Measures: Preliminary Analysis in the Adni Cohort
Deters, Kacie, Schwarz, Adam J. , Shcherbinin, Sergey, West, John D. , Jagust, William J. , Weiner, Michael W. , Saykin, Andy J., Initiative, Alzheimer's Disease Neuroimaging, Risacher, Shannon L. , Jack, Clifford R. , Saykin, Andy J., Initiative, Alzheimer's Disease Neuroimaging

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_6 | Pages: No page available

10.1016/j.jalz.2016.06.513 Get It

P1‐261: Association of [18F]AV‐1451 TAU Markers with Cognitive and Neurodegeneration Measures: Preliminary Analysis in The Adni Cohort
Deters, Kacie, Schwarz, Adam J. , Shcherbinin, Sergey, West, John D. , Jagust, William J. , Weiner, Michael W. , Saykin, Andy J., Initiative, Alzheimer's Disease Neuroimaging, Risacher, Shannon L. , Jack, Clifford R. , Saykin, Andy J., Initiative, Alzheimer's Disease Neuroimaging

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_10 | Pages: No page available

10.1016/j.jalz.2016.06.1010 Get It

A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers
Jack, Clifford R. , Bennett, David A. , Blennow, Kaj , Carrillo, María C. , Feldman, Howard , Frisoni, Giovanni B. , Hampel, Harald , Jagust, William J. , Johnson, Keith A. , Petersen, Ronald C. , Scheltens, Philip , Dubois, Bruno , Frisoni, Giovanni B. , Feldman, Howard H, Bennett, David A. , Knopman, David S. , Sperling, Reisa Anne , Jack, Clifford R , Scheltens, Philip , Feldman, Howard H

Neurology | July 1, 2016 | Volume: 87 | Issue: 5 | Pages: 539-547

10.1212/wnl.0000000000002923 Get It

O4‐05‐01: Gwas of longitudinal amyloid PET identifies IL1RAP as a new potential Alzheimer's disease target
Kim, Sungeun , Aisen, Paul, Petersen, Ronald C. , Jagust, William J. , Weiner, Michael W. , (ADNI), Alzheimer's Disease Neuroimaging Initiative, Ramanan, Vijay K. , Risacher, Shannon L. , Nho, Kwangsik T. , Shen, Li , Foroud, Tatiana , Toga, Arthur W. , Green, Robert C. , Saykin, Andrew J. , (ADNI), Alzheimer's Disease Neuroimaging Initiative

Alzheimer's & Dementia | December 15, 2015 | Volume: 11 | Issue: 7S_Part_6 | Pages: No page available

10.1016/j.jalz.2015.07.369 Get It

P3‐014: Influence of rare RELN variants on quantitative PET imaging and CSF phenotypes in late‐onset Alzheimer's disease
Aisen, Paul, Petersen, Ronald , Jagust, William J. , Shaw, Leslie M. , Trojanowski, John Q., Weiner, Michael W. , Greicius, Michael D. , Nho, Kwangsik T. , Kim, Sungeun , Risacher, Shannon L. , Foroud, Tatiana , Jack, Clifford R. , Trojanowski, John Q., Green, Robert C. , Toga, Arthur W. , Saykin, Andrew J.

Alzheimer's & Dementia | December 15, 2015 | Volume: 11 | Issue: 7S_Part_13 | Pages: No page available

10.1016/j.jalz.2015.06.880 Get It

IC‐P‐042: Influence of rare reelin variants on quantitative PET imaging and CSF phenotypes in late‐onset Alzheimer's disease
Aisen, Paul, Petersen, Ronald , Jagust, William J. , Shaw, Leslie M. , Trojanowski, John Q., Weiner, Michael W. , Greicius, Michael D. , Nho, Kwangsik T. , Kim, Sungeun , Risacher, Shannon L. , Foroud, Tatiana , Jack, Clifford R. , Trojanowski, John Q., Green, Robert C. , Toga, Arthur W. , Saykin, Andrew J.

Alzheimer's & Dementia | December 15, 2015 | Volume: 11 | Issue: 7S_Part_1 | Pages: No page available

10.1016/j.jalz.2015.06.062 Get It

IC‐P‐037: Association of cerebral microhemorrhages with amyloid deposition and hyperlipidemia
Kim, Sungeun , Jagust, William J. , Aisen, Paul, Petersen, Ronald C. , Weiner, Michael W. , (ADNI), Alzheimer's Disease Neuroimaging Initiative, Risacher, Shannon L. , Nho, Kwangsik T. , Jack, Clifford R. , Saykin, Andrew J. , (ADNI), Alzheimer's Disease Neuroimaging Initiative

Alzheimer's & Dementia | December 15, 2015 | Volume: 11 | Issue: 7S_Part_1 | Pages: No page available

10.1016/j.jalz.2015.06.057 Get It