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Wykosky, Jill

Mayo Clinic

Takeda (United States)

Citations 2

Mass cytometric analysis of circulating monocyte subsets in a murine model of diabetic gastroparesis
AlAsfoor, Shefaa , Jessen, Erik , Pullapantula, Suraj R., Voisin, Jennifer R., Hsi, Linda C., Farwana, Samera, Patraw, Jack A., Chai, Xin-yi, Ji, Sihan , Strausbauch, Michael, Cipriani, Gianluca , Wei, Lai , Hou, Ruixue , Myers, R , Bhattarai, Yogesh , Wykosky, Jill, Burns, Alan J. , Dasari, Surendra , Farrugia, Gianrico , Grover, Madhusudan , Chai, Xinyi , Strausbauch, Michael A, Bhattarai, Y , Farrugia, Gianrico , Grover, Madhusudan , Chai, Xin-Yi , Pavelko, Kevin D. , Farwana, Samera, Chai, Xin-yi, Linden, David R.

American Journal of Physiology-Gastrointestinal and Liver Physiology | February 14, 2025 | Volume: 328 | Issue: 4 | Pages: G323-G341

10.1152/ajpgi.00229.2024 Get It

Using 32 immune cell surface markers, we identified 23 monocyte clusters in murine blood. Diabetic gastroparesis was associated with a significant decrease in two circulating classical monocyte-like clusters and an upregulation of the Ccr2-Ccl2 axis in the gastric muscularis propria, suggesting increased tissue monocyte migration. This study offers new targets by pointing to a possible role for two classical monocyte subsets connected to the Ccr2- Ccl2 axis.
Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition
Shen, Ying , Nitta, Masayuki, Futalan, Diahnn, Treiber, Jeffrey M. , Taich, Zack, Stevens, Deanna M., Wykosky, Jill, Chen, Hong-Zhuan, Becher, Oren J. , Kennedy, Richard D. , Cavenee, Webster K. , Desai, Arshad , Chen, Clark C. , Li, Jie , Steed, Tyler , Taich, Zack, Carter, Bob S. , Esashi, Fumiko , Sarkaria, Jann N. , Furnari, Frank B.

Oncotarget | September 15, 2015 | Volume: 6 | Issue: 14 | Pages: 11751-11767

10.18632/oncotarget.3996 Get It