Citations 2
Bedside cognitive screening to detect dementia and predict poor outcomes in hospitals
Covinsky, Kenneth E. , Bertola, Laiss, Magaldi, Regina Miksian , Oh, Esther S., Carvalho, Bruna Macêdo de, Lima, Maria Eduarda Pires Lins e Silva, Almeida, Perola Quintans De, Melo, Victor José Dornelas, Pinheiro, Tatiana de Carvalho Espíndola , Lira, Raiza Tavares, Macedo, Ênio Simas , Yassuda, Mônica Sanches, Suemoto, Cláudia Kimie , Group, the CHANGE Study, Bertola, Laiss , Aliberti, Márlon J R , Suemoto, Claudia Kimie , Avelino‐Silva, Thiago Junqueira , Oh, Esther S , Carpenter, Christopher R. , Bicalho, Maria Aparecida Camargos , LIRA, RAÍZA TAVARES, Yassuda, Mônica Sanches
Alzheimer's & Dementia | March 20, 2026 | Volume: 22 | Issue: 3 | Pages: No page available
Abstract INTRODUCTION Cognitive impairment in hospitalized older adults without delirium is often undiagnosed. We evaluated the diagnostic accuracy and prognostic value of two brief bedside screening tools—the 10‐point Cognitive Screener (10‐CS) and Short Portable Mental Status Questionnaire (SPMSQ). METHODS Multicenter prospective cohort of 2003 patients ≥65 years of age without delirium, admitted to 43 hospitals in five countries of the Creating a Hospital Assessment Network in Geriatrics (CHANGE) Study. Screening was completed within 48 h of admission. Dementia was defined as informant‐based Clinical Dementia Rating ≥1. RESULTS Dementia prevalence was 22%, with 35% undiagnosed. Both tools showed good accuracy for detecting dementia, with the 10‐CS slightly more accurate than SPMSQ (area under the curve [AUC] = 0.87 vs 0.85; p = 0.02). After adjustment, cognitive impairment detected by either tool was associated with increased risk of incident delirium, hospital‐associated disability in self‐care activities, and 90‐day mortality, but not prolonged stay. DISCUSSION Brief bedside screening identified dementia and predicted adverse outcomes, supporting its integration into routine hospital care.
Advancements in dementia research, diagnostics, and care in Latin America: Highlights from the 2023 Alzheimer's Association International conference satellite symposium in Mexico City
Brucki, Sonia MD, Acosta, Daisy M, Carrillo, María C. , Mendez, Patricio Alexis Chrem , Cornejo‐Olivas, Mario , Custodio, Nilton , Duran‐Aniotz, Claudia , García, A.R. , Gonzales, Mitzi M. , Grinberg, Lea T. , Illanes‐Manrique, Maryenela , Jack, Clifford R. , Leon‐Salas, Jorge M, Luna‐Muñoz, José , Pericak‐Vance, Margaret A. , Resende, Elisa de Paula França , Ringman, John M. , Suemoto, Cláudia Kimie , Valcour, Victor , Villegas‐Lanau, Andrés, Sexton, Claire E. , Mahinrad, Simin , Sexton, Claire , Jack, Clifford R , Cornejo-Olivas, Mario , Grinberg, Lea , Suemoto, Claudia Kimie , Gonzales, Mitzi , Sosa, Ana Luisa , Crivelli, Lucía , Lopera, Francisco Javier , Acosta‐Uribe, Juliana , Aguilar, Diego, Aguilar-Navarro, Sara G. , Allegri, Ricardo , Bertolucci, Paulo Henrique Ferreira , Calandri, Ismael Luis , Damián, Andrés , Souza, Leonardo Cruz de , García‐Peña, Carmen , Ibáñez, Agustín , Llibre‐Guerra, Jorge J. , Matallana, Diana , Miller, Bruce L. , Naçi, Lorina , Parra, Mario A. , Piña‐Escudero, Stefanie Danielle , Sevlever, Gustavo Emilio , Slachevsky, Andrea , Yassuda, Mônica Sanches , Mahinrad, Simin
Alzheimer's & Dementia | May 27, 2024 | Volume: 20 | Issue: 7 | Pages: 5009-5026
AbstractINTRODUCTIONWhile Latin America (LatAm) is facing an increasing burden of dementia due to the rapid aging of the population, it remains underrepresented in dementia research, diagnostics, and care.METHODSIn 2023, the Alzheimer's Association hosted its eighth satellite symposium in Mexico, highlighting emerging dementia research, priorities, and challenges within LatAm.RESULTSSignificant initiatives in the region, including intracountry support, showcased their efforts in fostering national and international collaborations; genetic studies unveiled the unique genetic admixture in LatAm; researchers conducting emerging clinical trials discussed ongoing culturally specific interventions; and the urgent need to harmonize practices and studies, improve diagnosis and care, and use affordable biomarkers in the region was highlighted.DISCUSSIONThe myriad of topics discussed at the 2023 AAIC satellite symposium highlighted the growing research efforts in LatAm, providing valuable insights into dementia biology, genetics, epidemiology, treatment, and care.