Citations 1
Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma
Walker, Brian A. , Mavrommatis, Konstantinos , Wardell, Christopher P. , Ashby, Cody , Bauer, Michael , Davies, Faith E. , Hoering, Antje , Samur, Mehmet , Towfic, Fadi , Flynt, Erin , Yu, Zhinuan, Yang, Zhihong, Rozelle, Dan , Obenauer, John C. , Trotter, Matthew , Auclair, Daniel , Keats, Jonathan J. , Bolli, Niccolò , Fulciniti, Mariateresa , Szalat, Raphaël , Moreau, Philippe , Durie, Brian G.M. , Stewart, A. Keith, Goldschmidt, Hartmut , Sonneveld, Pieter , Miguel, Jesús F. San , Jackson, Graham , Avet‐Loiseau, Hervé , Munshi, Nikhil , Thakurta, Anjan , Morgan, Gareth J. , Moreau, Philippe , Bolli, Niccolo' , San-Miguel, Jesus , Davies, Faith E , Keats, Jonathan J , Walker, Brian A , Morgan, Gareth J , Rosenthal, Adam , Wang, Hongwei , Qu, Pingping , Ortiz, María , Raab, Marc S. , Einsele, Hermann , Lonial, Sagar , Anderson, Kenneth C. , Flynt, Erin , Samur, Mehmet K , Szalat, Raphael
Blood | June 8, 2018 | Volume: 132 | Issue: 6 | Pages: 587-597
Key Points Using the largest set of patients with newly diagnosed myeloma, we identified 63 mutated driver genes. We identified oncogenic dependencies, particularly relating to primary translocations, indicating a nonrandom accumulation of genetic hits.