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Boos, Alexander

0000-0002-5241-9191

Mayo Clinic

Mayo Clinic, Rochester, Minnesota, USA.

Citations 19

Long-term Outcomes After Surgical Reconstruction of Multiligamentous Knee Injuries: Results at Minimum 10-Year Follow-up
Boos, Alexander M. , Wang, Allen S. , Levy, Bruce A. , Wang, Allen , Boos, Alexander , Hevesi, Mario , Krych, Aaron J. , Stuart, Michael J.

Orthopaedic Journal of Sports Medicine | January 12, 2024 | Volume: 12 | Issue: 1 | Pages: No page available

10.1177/23259671231223188 Get It

Background: Multiligamentous knee injuries (MLKIs) are devastating injuries with concomitant injuries that complicate treatment and recovery. Short-term studies have shown satisfactory patient outcomes after surgical treatment; however, evaluations of long-term outcomes remain scarce. Purpose: To evaluate long-term outcomes after surgically reconstructed MLKIs and further investigate the relationship between patient age on clinical outcomes. Study Design: Case series; Level of evidence, 4. Methods: A total of 55 knees (age, 36 ± 11 years; 24% female subjects) who underwent surgical reconstruction for MLKI between 1992 and 2013 met the study inclusion criteria and were evaluated with postoperative patient-reported outcomes (PROs) including International Knee Documentation Committee (IKDC) score, Lysholm score, visual analog scale (VAS) for pain, Forgotten Joint Score, subjective improvement ratings and surgery satisfaction, and Tegner activity scores. PRO scores, revision, and conversion to arthroplasty were analyzed using descriptive statistics, linear regression, Wilcoxon rank-sum, and Fisher exact tests. Results: At final follow-up (mean, 15 ± 5 years; range, 10-31 years), 67% of the cohort reported subjective improvement in their knee, and 82% reported satisfaction with their surgery. Compared with preoperative scores, there were significant improvements in postoperative VAS pain at rest in the full cohort, age ≤30-year cohort, and age >30-year cohort (4 ± 1 vs 2 ± 2; 4 ± 1 vs 2 ± 3; 4 ± 1 vs 1 ± 2, respectively; P≤ .029 for all) but significant reductions in Tegner scores (6 ± 3 vs 4 ± 2; 7 ± 2 vs 5 ± 2; 5 ± 2 vs 3 ± 1; P≤ .003 for all). Younger patients had higher postoperative Tegner scores than older patients (5 ± 2 vs 3 ± 1, respectively; P = .003), but no other differences in PROs were observed based on age. At a mean 15-year follow-up, 3.6% of the cohort underwent revision ligament surgery and 10.9% required arthroplasty. Conclusion: The majority of the cohort reported modest subjective improvement and were satisfied with their surgery. Gradual but expected age-related decreases in Tegner scores were observed, and some patients demonstrated continued symptomatic and functional limitations, but mean PRO scores remained satisfactory. Revision surgery and conversion to arthroplasty were not commonly required.
Minimally Invasive Quadriceps Tendon Anterior Cruciate Ligament Reconstruction Using the Quadriceps Tendon Harvest Guide System
Dancy, Malik E. , Davis, Michelle A. , Meta, Fabien , Wang, Allen S. , Boos, Alexander M. , Camp, Christopher L. , Hevesi, Mario , Okoroha, Kelechi R. , Camp, Christopher L. , Wang, Allen , Boos, Alexander , Hevesi, Mario , Davis, Michelle A.

Arthroscopy Techniques | January 1, 2024 | Volume: 13 | Issue: 3 | Pages: No page available

10.1016/j.eats.2023.11.009 Get It

Abstract Anterior cruciate ligament (ACL) reconstruction using the quadriceps tendon (QT) autograft is an increasingly utilized technique that confers less donor site morbidity and comparable outcomes to other historically used graft options. The graft harvest and implantation process present vast variability—particularly regarding the achievement of adequate graft site visualization, consistently attaining a uniform and appropriately sized graft, and subsequent reconstruction of the ACL with the all‐soft tissue graft. The purpose of this Technical Note and video is to describe and demonstrate minimally invasive quadriceps tendon autograft harvesting using the Quadriceps Tendon Harvest Guide System (QUADTRAC), and its subsequent implantation within a single‐bundle ACL reconstruction with suspensory fixation. Technique Video video See video under supplementary data.
Medial Collateral Ligament Reconstruction of the Knee: The Modified Marx Technique With Adjustable‐Loop Femoral Fixation and Posteromedial Corner Plication
Boos, Alexander M. , Hevesi, Mario , Wang, Allen S. , Fiegen, Anthony P. , Levy, Bruce A. , Wang, Allen , Boos, Alexander , Hevesi, Mario

Arthroscopy Techniques | December 25, 2023 | Volume: 13 | Issue: 1 | Pages: No page available

10.1016/j.eats.2023.09.007 Get It

Abstract The medial collateral ligament serves as the primary stabilizer to valgus stress on the medial side of the knee and is the most commonly injured ligament in the knee. Medial collateral ligament reconstruction can provide improved stability and clinical outcomes for patients. Advancements in techniques, including the use of an adjustable‐length‐loop suspensory fixation device through a longitudinal incision, have been introduced in recent years. The purpose of this Technical Note and video is to provide a minimally invasive method for medial collateral ligament reconstruction with adjustable‐loop femoral fixation and posteromedial corner plication. Technique Video video See video under supplementary data.
Minimally Invasive Quadriceps Tendon Harvest for Anterior Cruciate Ligament Reconstruction Using the Quadriceps Tendon Harvest Guide (QUADTRAC) System and Repair Augmentation With a Bioinductive Implant
Wang, Allen S. , Boos, Alexander M. , Dancy, Malik E. , Camp, Christopher L. , Hevesi, Mario , Okoroha, Kelechi R. , Camp, Christopher L. , Wang, Allen , Boos, Alexander , Hevesi, Mario

Arthroscopy Techniques | December 4, 2023 | Volume: 13 | Issue: 1 | Pages: No page available

10.1016/j.eats.2023.08.017 Get It

Abstract Quadriceps tendon autografts are an increasingly popular choice for anterior cruciate ligament (ACL) reconstruction, with decreased donor‐site morbidity alongside good patient outcomes. Although harvesting of the tendon can be done in a minimally invasive fashion, this introduces some difficulty with visualization and consistency of graft sizing. The purpose of this Technical Note and video is to provide a method of quadriceps tendon autograft harvesting using the Quadriceps Tendon Harvest Guide System (QUADTRAC) in a single‐bundle ACL reconstruction. Technique Video video See video under supplementary data.
Isolated Arthroscopic Debridement of Acetabular Labral Tears: High Rates of Failure and Conversion to Total Hip Arthroplasty at 13-Year Minimum Follow-up
Lamba, Abhinav , Boos, Alexander M. , Okoroha, Kelechi R. , Stuart, Michael J. , Levy, Bruce A. , Krych, Aaron J. , Krych, Aaron J , Stuart, Michael J , Lamba, Abhinav , Boos, Alexander , Hevesi, Mario

The American Journal of Sports Medicine | October 13, 2023 | Volume: 52 | Issue: 1 | Pages: 18-23

10.1177/03635465231204345 Get It

Background: Historically, symptomatic hip labral lesions were treated with arthroscopic debridement. Hip labral repair has become the standard treatment for labral pathology; however, to date, there are limited long-term studies regarding the outcomes of isolated labral debridement. Purpose: To (1) evaluate the long-term patient-reported outcomes of isolated labral debridement, (2) report reoperation and arthroplasty rates, and (3) identify risk factors contributing to reoperation or poor clinical outcomes. Study Design: Case series; Level of evidence, 4 Methods: A retrospective review of a prospectively generated cohort of 59 hips in 57 patients from 1996 to 2010 who underwent hip arthroscopy with labral debridement was performed. Only patients with Tönnis grade <3 were included. Additionally, given the time period analyzed, resection of cam morphology was not performed, and the interportal capsulotomy was not repaired. The pre- and postoperative modified Harris Hip Score; Hip Outcome Score (HOS)-Activities of Daily Living and -Sports scores; and reoperation, conversion to total hip arthroplasty, and risk factors were analyzed. Results: In total, 48 hips in 47 patients (14 men, 33 women; mean age, 48.0 ± 12.9 years) met inclusion criteria and were followed for a mean of 17 ± 3 years (range, 13-27 years). The mean preoperative Tönnis grade was 1.3 ± 0.6 (range, 0-2), the mean chondral acetabular International Cartilage Regeneration & Joint Preservation Society (ICRS) grade was 1.7 ± 1.6 (range, 0-4), the mean chondral femoral ICRS grade was 0.9 ± 1.4, and the mean acetabular labral articular cartilage grade was 2.5 ± 1.2 (range, 0-4). At the final follow-up, mean the modified Harris Hip Score, HOS-Activities of Daily Living score, and HOS-Sports score were 82.2 ± 16.6, 81.9 ± 20.5, and 82.2 ± 20.5, respectively. Nineteen hips underwent subsequent reoperation at a mean of 5.5 ± 6.2 years (range, 0.5-21.2 years) postoperatively, including 16 hips (33% overall) being converted to total hip arthroplasty. Higher acetabular ICRS chondral grades at the time of surgery were observed in patients who went on to subsequent surgery compared with those who did not (2.3 ± 1.6 vs 1.1 ± 1.5; P = .02). In reoperation-free hips, Tönnis grade demonstrated a trend of increasing over time (1.4 preoperatively vs 1.7 at radiographic follow-up; P = .08). At the final follow-up, 19 hips (40%) had undergone reoperation, and 5 additional hips (10%) were rated as “abnormal” or “severely abnormal” in function, resulting in an overall clinical failure rate of 50%. Conclusion: Isolated labral debridement was found to result in high rates of failure and reoperation, with a third of patients being converted to arthroplasty and half of patients meeting criteria for reoperation or clinical failure. Of note, for patients remaining reoperation-free, satisfactory outcome scores were observed.
Satisfactory Clinical Outcome, Complications, and Provisional Results of Meniscus Centralization with Medial Meniscus Root Repair for the Extruded Medial Meniscus at Mean 2‐Year Follow‐Up
Krych, Aaron J. , Boos, Alexander M. , Lamba, Abhinav , Smith, Patrick A. , Krych, Aaron J , Lamba, Abhinav , Boos, Alexander

Arthroscopy | October 11, 2023 | Volume: 40 | Issue: 5 | Pages: 1578-1587

10.1016/j.arthro.2023.10.003 Get It

Purpose To describe the patient‐reported clinical outcomes following medial meniscus root repair with meniscus centralization and to identify common complications and detail provisional results. Methods Patients undergoing medial meniscus root repair with meniscus centralization from 2020 to 2022 were identified using an institutional database. Patients were followed prospectively using postoperative Tegner Activity Scale, visual analog scale (VAS) for pain, Knee Injury and Osteoarthritis Outcome Score, Joint Replacement, International Knee Documentation Committee score, and a Likert score for improvement, surgery satisfaction, and subsequent surgeries at minimum 1‐year follow‐up with mean 2‐year follow‐up. Demographics, injury characteristics, and surgical details were also collected. Results Twenty‐five patients (age: 50 ± 11 years; sex: 76% female; body mass index: 33 ± 8) were included in this study. Postoperative Tegner score was maintained at preoperative levels ( P = .233), and VAS at rest, VAS with use, Knee Injury and Osteoarthritis Outcome Score, Joint Replacement, and International Knee Documentation Committee improved significantly postoperatively ( P = .003; P < .001, P < .001, P = .023, respectively). Eighty‐eight percent of patients reported subjective improvement in their knee at final follow‐up. Postoperative radiographs did not show any significant osteoarthritis progression, and no patients had undergone a revision meniscus surgery or total knee arthroplasty at the time of follow‐up. Conclusions At minimum 1‐year follow‐up and mean 2‐year follow‐up, patients undergoing medial meniscus root repair with meniscus centralization demonstrated significant postoperative improvements in pain, function, and quality of life and reported high rates of surgery satisfaction. There was no evidence of significant arthritic progression on postoperative imaging, and no patients underwent revision meniscus surgery or total knee arthroplasty. Level of Evidence Level IV, case series.
Satisfactory Outcomes and Improved Range of Motion With Arthroscopic Lysis of Adhesions and Manipulation for Arthrofibrosis After Multiligamentous Knee Reconstruction
Lamba, Abhinav , Boos, Alexander M. , Krych, Aaron J. , Stuart, Michael J. , Hevesi, Mario , Levy, Bruce A. , Krych, Aaron J , Stuart, Michael J , Lamba, Abhinav , Boos, Alexander , Hevesi, Mario

Arthroscopy, Sports Medicine, and Rehabilitation | September 4, 2023 | Volume: 5 | Issue: 5 | Pages: No page available

10.1016/j.asmr.2023.100784 Get It

Purpose To (1) evaluate the efficacy of surgery for arthrofibrosis (AF), as measured by preoperative and postoperative range of motion (ROM), and (2) evaluate patient‐reported outcomes at mid‐ to long‐term follow‐up. Methods We performed a retrospective review of a prospectively collected database including patients who sustained multiligamentous knee injuries (MLKIs) managed surgically, sustained loss of ROM after surgical intervention, and underwent subsequent lysis of adhesions (LOA) and/or manipulation under anesthesia (MUA). Loss of ROM was defined as clinically symptomatic loss of terminal extension (flexion deformity) and/or flexion compared with the contralateral side. Results In total, 12 patients (6 male and 6 female patients; age, 36.0 ± 8.7 years; body mass index, 36.3 ± 8.7) met the inclusion criteria and underwent LOA and/or MUA at a mean of 14 ± 27 months (median, 4.0 months; interquartile range, 3.5‐9.3 months) after MLKI surgery. Prior to AF intervention, patients showed mean flexion of 75.9° ± 36.0° (range, 30°‐129°), mean extension of 3.2° ± 5.2° (range, 0°‐12°), and a mean arc of motion of 72.7° ± 34.1° (range, 30°‐117°). At a mean follow‐up of 7.0 ± 3.9 years (range, 2.4‐16.6 years) after AF intervention, patients showed a significant increase in knee flexion of 49° ( P = .003), a significant increase in arc of motion of 51° ( P = .002), and an increase in extension of 3° ( P = .086). The mean final International Knee Documentation Committee score was 59.5 ± 23.9; Lysholm score, 72.1 ± 20.6; Tegner activity scale score, 5.6 ± 2.8; visual analog scale score at rest, 1.0 ± 1.6; and visual analog scale score with use, 3.3 ± 2.5. At final follow‐up, 2 patients (17%) had undergone conversion to total knee arthroplasty (TKA) at 10.3 and 24.8 years after MLKI surgery. Of the 10 patients who did not go on to TKA, 9 (90%) reported that they were satisfied or very satisfied with their AF knee surgery. Conclusions At mid‐term follow‐up, LOA and/or MUA for symptomatic AF after multiligamentous knee surgery results in high rates of patient satisfaction and improved knee ROM and pain scores, as well as durable and satisfactory functional outcomes in patients not undergoing TKA. Level of Evidence Level IV, therapeutic case series.
Artificial Intelligence Can Define and Predict the “Optimal Observed Outcome” After Anterior Shoulder Instability Surgery: An Analysis of 200 Patients With 11‐Year Mean Follow‐Up
Till, Sara E., Lu, Yining , Reinholz, Anna K., Boos, Alexander M. , Krych, Aaron J. , Okoroha, Kelechi R. , Camp, Christopher L. , Lu, Yining , Camp, Christopher L. , Krych, Aaron J , Boos, Alexander

Arthroscopy, Sports Medicine, and Rehabilitation | July 22, 2023 | Volume: 5 | Issue: 4 | Pages: No page available

10.1016/j.asmr.2023.100773 Get It

Purpose To use unsupervised machine learning clustering to define the “optimal observed outcome” after surgery for anterior shoulder instability (ASI) and to identify predictors for achieving it. Methods Medical records, images, and operative reports were reviewed for patients <40 years old undergoing surgery for ASI. Four unsupervised machine learning clustering algorithms partitioned subjects into “optimal observed outcome” or “suboptimal outcome” based on combinations of actually observed outcomes. Demographic, clinical, and treatment variables were compared between groups using descriptive statistics and Kaplan‐Meier survival curves. Variables were assessed for prognostic value through multivariate stepwise logistic regression. Results Two hundred patients with a mean follow‐up of 11 years were included. Of these, 146 (64%) obtained the “optimal observed outcome,” characterized by decreased: postoperative pain (23% vs 52%; P < 0.001), recurrent instability (12% vs 41%; P < 0.001), revision surgery (10% vs 24%; P = 0.015), osteoarthritis (OA) (5% vs 19%; P = 0.005), and restricted motion (161° vs 168°; P = 0.001). Forty‐one percent of patients had a “perfect outcome,” defined as ideal performance across all outcomes. Time from initial instability to presentation (odds ratio [OR] = 0.96; 95% confidence interval [CI], 0.92‐0.98; P = 0.006) and habitual/voluntary instability (OR = 0.17; 95% CI, 0.04‐0.77; P = 0.020) were negative predictors of achieving the “optimal observed outcome.” A predilection toward subluxations rather than dislocations before surgery (OR = 1.30; 95% CI, 1.02‐1.65; P = 0.030) was a positive predictor. Type of surgery performed was not a significant predictor. Conclusions After surgery for ASI, 64% of patients achieved the “optimal observed outcome” defined as minimal postoperative pain, no recurrent instability or OA, low revision surgery rates, and increased range of motion, of whom only 41% achieved a “perfect outcome.” Positive predictors were shorter time to presentation and predilection toward preoperative subluxations over dislocations. Level of Evidence Level IV, retrospective cohort.
Nonoperative Management of Degenerative Medial Meniscus Posterior Root Tears: Poor Outcomes at a Minimum 10-Year Follow-up
Krych, Aaron J. , Lamba, Abhinav , Wang, Allen S. , Boos, Alexander M. , Camp, Christopher L. , Levy, Bruce A. , Stuart, Michael J. , Camp, Christopher L. , Krych, Aaron J , Stuart, Michael J , Wang, Allen , Lamba, Abhinav , Boos, Alexander , Hevesi, Mario

The American Journal of Sports Medicine | July 12, 2023 | Volume: 51 | Issue: 10 | Pages: 2603-2607

10.1177/03635465231185132 Get It

Background: Medial meniscus posterior root tears (MMPRTs) cause pain and dysfunction and are associated with poor clinical outcomes with nonoperative management at short-term follow-up. However, little is known about the long-term natural history of these tears. Purpose: The purpose of this study was to (1) provide an update to a previous minimum 2-year study on the natural progression of these tears and (2) evaluate long-term patient-reported and radiographic outcomes. Study Design: Case series (prognosis); Level of evidence, 4. Methods: A retrospective review was performed on a cohort of patients with untreated MMPRTs, diagnosed between 2005 and 2013, who were followed clinically using International Knee Documentation Committee (IKDC), visual analog scale for pain, and Tegner activity scores as well as radiographically at a minimum 10-year follow-up. Failure was defined as conversion to arthroplasty or a severely abnormal subjective IKDC score <75.4. Results: Overall, 5 (10%) of the original 52 patients with minimum 2-year outcomes were subsequently lost to follow-up. The remaining 47 patients (21 male, 26 female) were followed for a mean of 14 ± 2 years (range, 11-18 years). At final follow-up, 25 patients (53%) had progressed to total knee arthroplasty, 8 (17%) were deceased, and 14 (30%) had not progressed to total knee arthroplasty. The mean IKDC and Tegner activity scores for the 14 patients with remaining MMPRTs were 51.6 ± 22.2 and 3.1 ± 1.1, respectively, and the mean visual analog scale score was 4.4 ± 3.0. Radiographically, the mean Kellgren-Lawrence grade progressed from 1.2 ± 0.7 at baseline to 2.6 ± 0.5 at final follow-up ( P < .001). At a minimum 10-year follow-up, 37 of 39 living patients (95%) had failed nonoperative treatment. Conclusion: Poor clinical and radiographic outcomes were associated with the nonoperative treatment of degenerative MMPRTs at long-term follow-up. This study provides a valuable update on the natural history and long-term prognosis of nonoperatively treated MMPRTs.