Citations 1
Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia
He, Bai‐Liang , Shi, Xiangguo , Man, Cheuk Him , C.H., Alvin, Ekker, Stephen C. , Chow, Howard C.H., So, Chi Wai Eric , Choi, William W.L., Leung, Anskar Y.H. , Zhang, Wenqing , Zhang, Yiyue , Alvin, C. H. , Ekker, Stephen C
Blood | March 4, 2014 | Volume: 123 | Issue: 16 | Pages: 2518-2529
Key Points Zebrafish flt3 plays an important role in the initiation of definitive hematopoietic stem cells. Expression of human FLT3-ITD activates endogenous flt3 signaling and induces myeloid expansion.