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Hamadi, Hanadi Y

0000-0001-9050-7267

Mayo Clinic

University of North Florida

Citations 21

Does concurrent pharmacotherapy enhance behavioral interventions for mild cognitive impairment? Evidence from the HABIT program
Xie, Zhigang , Locke, Dona E.C. , Shandera-Ochsner, Anni, Hamadi, Hanadi , Santos, Octavio, Boots, Elizabeth A., Aghamoosa, Stephanie , Grant, Jeremy, Smith, Glenn, Chandler, Melanie, Grant, Jeremy , Locke, Dona E C , Hamadi, Hanadi Y , Wit, Liselotte De , Boots, Elizabeth A. , Grant, Jeremy, Smith, Glenn E. , Chandler, Melanie

Journal of Alzheimer’s Disease | July 27, 2026 | Volume: No volume available | Issue: No issue available | Pages: No page available

10.1177/13872877261471921 Get It

Background Mild cognitive impairment (MCI) represents a critical window for both pharmacological therapies and non-pharmacological interventions to delay cognitive decline. Objective To evaluate whether combining pharmacotherapy with multicomponent behavioral interventions enhances outcomes relative to behavioral interventions alone. Methods The sample included people with MCI (pwMCI) of any etiology who completed the HABIT Healthy Action to Benefit Independence & Thinking ® program. Baseline pharmacotherapy (acetylcholinesterase inhibitor and/or glutamate regulators) use was dichotomized (yes/no). Multivariate linear mixed-effects models examined changes from baseline in care partner-reported everyday functional skills, quality of life, self-efficacy, anxiety, depression, and HABIT compliance at post-intervention, 6 months, and 12 months, adjusting for baseline cognitive impairment severity and relevant demographic covariates. Results Among 1074 pwMCI, 413 (38.5%) were receiving pharmacotherapy at baseline. Pharmacotherapy use was more prevalent among White than non-White participants (39.4% versus 23.3%, p = 0.01). At baseline, pharmacotherapy users had more severe cognitive impairment and lower utilization of rehabilitation strategies (all p < 0.05). Both groups demonstrated significant improvements across all outcomes at post-intervention. During follow-up (mean score change compared to baseline), pharmacotherapy users showed greater increases in HABIT compliance at 6 months (3.2 versus 2.0) and 12 months (2.1 versus 1.4). In contrast, by 12 months, pharmacotherapy users experienced greater worsening of everyday functional skills related to memory (−2.1 versus −1.3) and executive function (−5.8 versus-3.7). Conclusions pwMCI undergoing pharmacotherapy entered the HABIT program with more advanced cognitive impairment. The pharmacotherapy was not associated with greater intervention-related benefit or attenuation of long-term cognitive decline.
Social Determinants of Health and Patient Experiences During Transitions From Inpatient Rehabilitation to Home
Hamadi, Hanadi , Bailey, Chloe , Manes, Mindi , Paris, Trevor , Kendall, Heather A. , Park, Sinyoung , Hicks-Roof, Kristen, Spaulding, Aaron , Hamadi, Hanadi Y , Bailey, Chloe E , Manes, Mindi R , Xu, Jing , Hicks-Roof, Kristen K

Journal of Patient Experience | June 17, 2026 | Volume: 13 | Issue: No issue available | Pages: No page available

10.1177/23743735261462042 Get It

Transitions from inpatient rehabilitation to home critically affect patient recovery and caregiver well-being. Social determinants of health (SDoH) shape these outcomes yet remain underexamined in rehabilitation settings. The objective of this study was to examine the prevalence of SDoH on patient and caregiver experiences during the first 30 days following discharge from a multi-site inpatient rehabilitation facility in the southeastern United States and explore patterns of patient satisfaction and caregiver burden that can influence care transitions. A prospective cross-sectional descriptive study surveyed 61 patients and 50 caregivers using validated instruments assessing SDoH, communication, discharge preparedness, and caregiver burden. Social isolation, affecting 18% of patients and 10% of caregivers, was the most prevalent challenge. Additional challenges include health literacy and transportation barriers. Caregivers experienced substantial burden: 60% decline in social activities, 50% decreased energy, and 40.9% negative physical health effects. However, 58.1% reported strengthened patient relationships. This study identifies the importance of care continuity and SDoHs after inpatient rehabilitation. Interdisciplinary interventions focused on these key challenges are essential for improving outcomes.
Physician employment and hospital readmission and mortality outcomes: an organizational perspective
Green, S J, Hamadi, Hanadi , Zhao, Mei, Spaulding, Aaron , Green, Shawna , Spaulding, Aaron , Hamadi, Hanadi Y , Zhao, Mei

Journal of Health Organization and Management | June 17, 2026 | Volume: No volume available | Issue: No issue available | Pages: 1-12

10.1108/jhom-02-2026-0209 Get It

Purpose To assess if hospitals with high physician employment differ in risk-standardized mortality and readmission rates. Design/methodology/approach A cross-sectional evaluation of data from the 2021 Hospital Readmission Reduction program, Hospital Value-Based Purchasing Program, American Hospital Association and Area Health Resource Files was utilized. A binary variable was created to identify hospitals with ≤ 50% or &gt;50% employed physicians. Dependent variables included 30-day mortality and readmission rates for acute myocardial infarction (AMI), congestive heart failure (CHF), pneumonia (PN), and chronic obstructive pulmonary disease (COPD) hospitalizations. Propensity score matching was utilized to compare hospitals. The final matched cohort compared 200 hospitals in each group ( ≤ 50% physicians and &gt; 50% physicians). Findings After matching, hospitals with &gt; 50% physician employment were associated with improved mortality scores for AMI (−0.36, 95% CI: −0.58, −0.14), COPD (−0.38, 95% CI: −0.63, −0.14), and PN (−0.71, 95% CI: −1.15, −0.27). No significant differences were noted for CHF mortality or readmission rates. Originality/value There has been a growth in hospitals employing physician in the United States. This work demonstrates that hospitals with higher physician employment levels are associated with lower mortality scores. This likely reflects a broader organizational phenotype characterized by alignment, scale and clinical integration rather than physician employment as an isolated strategy. Further research should examine organizational features to better disentangle the structure and combination of organizational characteristics underlying these associations.
Exploring Risk and Protective Factors: Understanding Nonmedical Stimulant Use Among Florida High School Students
Hamadi, Hanadi , Thomas, Rachel McMahan, Xie, Zhigang, Patterson, Karen B., Spaulding, Aaron, Spaulding, Aaron , Spaulding, Aaron , Hamadi, Hanadi Y , Thomas, Rachel McMahan, Xie, Zhigang, Patterson, Karen B.

Journal of Drug Issues | July 29, 2025 | Volume: No volume available | Issue: No issue available | Pages: No page available

10.1177/00220426251364375 Get It

Nonmedical stimulant use (NMSU) among adolescents poses significant public health concerns. Using cross-sectional design, this study examined risk and protective factors for NMSU among 20,576 Florida high school students using the 2020 Florida Youth Substance Abuse Survey, with 925 students reporting NMSU. Guided by Hawkins and Catalano’s Social Development Model, we employed multivariate logistic regression analyses to estimate adjusted odds ratios while controlling for demographics. Students engaged in extracurricular activities were 50% less likely to report NMSU. Higher academic performance was associated with lower NMSU likelihood. Students with friends who used stimulants nonmedically were significantly more likely to engage in NMSU (AOR, 7.60; 95% CI: 6.35, 9.10), as were those living with relatives who used substances (AOR, 3.54; 95% CI: 2.94, 4.26). Findings highlight the importance of extracurricular involvement and positive social networks in mitigating NMSU. Interventions addressing family, peers, and extracurricular involvement are crucial for prevention and evidence-based policies.
Hospital–Community Partnerships and 30-Day All-Cause Readmission Rates in High-Need and Low-Need Communities
Park, Sinyoung , Hamadi, Hanadi , Carrier, Allison , Xu, Jing , Spaulding, Aaron , Zhao, Mei , Hamadi, Hanadi Y , Spaulding, Aaron , Zhao, Mei

Hospital Topics | May 16, 2025 | Volume: No volume available | Issue: No issue available | Pages: 1-10

10.1080/00185868.2025.2504377 Get It

Unlocking The Potential: Telehealth Services and Social Determinants of Health Outcomes in Health Care Delivery
Hamadi, Hanadi , Zhao, Mei , Sam, Franscisca, Murphy, Bryan, Niazi, Shehzad K. , Spaulding, Aaron , Hamadi, Hanadi Y , Niazi, Shehzad, Spaulding, Aaron C. , Spaulding, Aaron , Murphy, Bryan

Telemedicine and e-Health | February 17, 2025 | Volume: 31 | Issue: 6 | Pages: 758-764

10.1089/tmj.2024.0358 Get It

Background: Unmet social needs may hinder health care providers’ ability to deliver suitable care. Telehealth has emerged as a mechanism to broaden care reach; however, limited studies have examined the relationships between telehealth services and social need outcomes. This study explores the impact of telehealth services, encompassing (1) telestroke, (2) telepsychiatry and addiction treatment, (3) teleconsultation and office visits,(4) tele-intensive care units, (5) telemonitoring postdischarge, (6) ongoing chronic care management, and (7) other remote monitoring, on social need performance outcomes. Methods: The 2022 American Hospital Association annual survey and the Area Health Resource Files, which include comprehensive hospital and community indicators, were utilized. A mixed-effects logistic regression was applied, analyzing 1,005 acute care general hospitals. Results: The results revealed that patients who received telemonitoring services after discharge were 1.72 (95% confidence interval [CI]: 1.03-2.88) times more likely to achieve better health outcomes compared with those who did not receive such services. These patients also experienced a significant decrease in the likelihood of requiring additional hospital or system services, with an odds ratio of 2.39 (95% CI: 1.32-4.00). Additionally, patients utilizing telepsychiatry and addiction treatment services had 1.66 times higher odds of reporting improved community health status (95% CI: 1.22-2.27). Lastly, patients who used teleconsultation and office visit services had 38% lower odds of experiencing poor community health status (95% CI: 0.40-0.95). Discussion: The findings highlight the potential of targeted telehealth services to positively impact health outcomes, reduce health care costs, and improve community health status.
Inpatient Palliative Care and Healthcare Utilization Among Older Patients With Alzheimer’s Disease and Related Dementia (ADRD) and High Risk of Mortality in U.S. Hospitals
Xie, Zhigang , Chen, Guanming , Hamadi, Hanadi , Montgomery, Lucinda, Robinson, Maisha T. , Hong, Young‐Rock , Hamadi, Hanadi Y , Hong, Young-Rock , Oladeru, Oluwadamilola T.

American Journal of Hospice and Palliative Medicine® | May 6, 2024 | Volume: 42 | Issue: 3 | Pages: 261-272

10.1177/10499091241252685 Get It

Background . Despite the potential of palliative care (PC) to enhance the quality of life for patients with advanced dementia, there is limited knowledge of its inpatient utilization patterns. This study investigated inpatient PC consultation utilization patterns and evaluated its impact on hospital length of stay (LOS) and medical costs among older patients diagnosed with Alzheimer’s Disease and Related Dementia who were at a high risk of mortality (ADRD-HRM). Methods . Using the 2016-2019 National Inpatient Sample database, we conducted multivariable logistic regression analyses to identify individual and hospital characteristics influencing PC consultation utilization. We subsequently performed generalized linear models to estimate LOS (using Poisson distribution) and hospital charges (via log-transformation). Results . Our sample encompassed 965,644 hospital discharges (weighted n = 4,828,219) of patients aged 65 years and above with ADRD-HRM. Among them, 14.6% received inpatient PC. There was a notable uptrend in PC consultation utilization from 13.3% in 2016 to 16.3% in 2019 ( p trend<.001). Factors positively influencing and associated with PC utilization included patients that are older, non-Hispanic White, with higher income, receiving care from teaching hospitals, and facilitated with greater bed capacity (all P < .05). Although patients who received PC were more likely to have 3.0% longer LOS ( P < .001), they had 19.2% lower hospital charges ( P < .001). Conclusions . PC substantially reduced hospital expenditures for older patients with ADRD-HRM, but the prevalence remained low at 14.6% in the study period. Future studies should explore the unmet needs of patients with lower sociodemographic status and those in rural hospitals to further increase their PC consultation utilization.
Improving Health and Addressing Social Determinants of Health Through Hospital Partnerships
Hamadi, Hanadi , Zhao, Mei , Park, Sinyoung , Xu, Jing , Haley, D. Rob , Lox, Curt , Spaulding, Aaron , Hamadi, Hanadi Y , Haley, Donald Rob , Spaulding, Aaron , Zhao, Mei

Population Health Management | March 1, 2023 | Volume: 26 | Issue: 2 | Pages: 121-127

10.1089/pop.2023.0002 Get It

Hospitals and health systems are forming partnerships to develop an integrated social network of services that better address the needs of their surrounding communities and their social determinants of health (SDOH). There is little research on the association of these partnered services with hospital outcomes. This study examined the association between hospital social need partnerships and activities to improve hospital and community outcomes. A secondary cross-sectional design to analyze 2021 census data of nonfederal short-term acute care hospitals in the United States was utilized. Data were obtained from the American Hospital Association. Four multilevel logistic regression models were used to analyze data from 1005 hospitals. The authors found that hospital partnership type differed in association to social need outcomes. They found that hospitals with a partnership with health insurance providers were more likely to have better health outcomes. Hospitals partnered with health insurance providers, local organizations addressing housing insecurity, local businesses, or chambers of commerce were more likely to have decreased health care costs. Hospitals partnered with health care providers, health insurance providers, local organizations providing legal assistance, or law enforcement/safety forces were more likely to have decreased utilization of hospital services. However, hospitals partnered with other local or state government or social service organizations were less likely to indicate decreased utilization of services. Many hospitals and health systems across the United States are screening for SDOH and are advancing health care delivery and improving the community's overall health and well-being by identifying unmet social needs and partnering with the community to address them.
COVID-19 Deaths and the Impact of Health Disparities, Hospital Characteristics, Community, Social Distancing, and Health System Competition
Zhao, Mei , Hamadi, Hanadi , Haley, D. Rob , Xu, Jing , Tafili, Aurora , Spaulding, Aaron , Hamadi, Hanadi Y , Spaulding, Aaron , Haley, Donald Rob , Zhao, Mei

Population Health Management | December 28, 2022 | Volume: 25 | Issue: 6 | Pages: 807-813

10.1089/pop.2022.0144 Get It

The United States has one of the highest cumulative mortalities of coronavirus disease 2019 (COVID-19) and has reached 1 million deaths as of May 19th, 2022. Understanding which community and hospital factors contributed to disparities in COVID-19 mortality is important to inform public health strategies. This study aimed to explore the potential relationship between hospital service area (1) community (ie, health professional shortage areas, market competition, and uninsured percentage) and (2) hospital (ie, teaching, system, and ownership status) characteristics (2013–2018) on publicly available COVD-19 (February to October 2020) mortality data. The study included 2514 health service areas and used multilevel mixed-effects linear model to account for the multilevel data structure. The outcome measure was the number of COVID-19 deaths. This study found that public health, as opposed to acute care provision, was associated with community health and, ultimately, COVID-19 mortality. The study found that population characteristics including more uninsured greater proportion of those over 65 years, more diverse populations, and larger populations were all associated with a higher rate of death. In addition, communities with fewer hospitals were associated with a lower rate of death. When considering region in the United States, the west region showed a higher rate of death than all other regions. The association between some community characteristics and higher COVID-19 deaths demonstrated that access to health care, either for COVID-19 infection or worse health from higher disease burden, is strongly associated with COVID-19 deaths. Thus, to be better prepared for potential future pandemics, a greater emphasis on public health infrastructure is needed.
The role of community‐level characteristics in comparing United States hospital performance by magnet designation: A propensity score matched study
Hamadi, Hanadi , Boamah, Sheila A. , Dorsey, Katherine, Zhao, Mei , Spaulding, Aaron , Menser, Terri , Hamadi, Hanadi Y , Boamah, Sheila A , Zhao, Mei , Spaulding, Aaron

Journal of Advanced Nursing | September 24, 2022 | Volume: 79 | Issue: 5 | Pages: 1939-1948

10.1111/jan.15446 Get It

Abstract Aims To assess the impact of community‐level characteristics on the role of magnet designation in relation to hospital value‐based purchasing quality scores, as health disparities associated with geographical location could confound hospitals' ability to meet outcome metrics. Design This cross‐sectional study was carried out between October 2021 and March 2022 using data from 2016 to 2021. Methods Propensity score analysis was used to match hospital and community‐level characteristics, implementing nearest neighbour matching to adjust for pre‐treatment differences between magnet and non‐magnet hospitals to account for multi‐level differences. Secondary data were obtained from all operational acute‐care facilities in the United States that participated in the Centers for Medicare and Medicaid Services' hospital value‐based purchasing (HVBP) program. Dependent variables were the four value‐based purchasing domains that comprise the Total Performance Score (TPS; Clinical Care, Person and Community Engagement, Safety, and Efficiency and Cost Reduction). Results Magnet hospitals had increased odds for better scores in the HVBP domains of Clinical Care and Person and Community Engagement, and decreased odds for having better Safety. However, no statistically significant difference was found for the Efficiency domain or the TPS. Conclusion Measuring performance equitably across organizations of various sizes serving diverse communities remains a key factor in ensuring distributive justice. Analysing the TPS components can identify complex influences of community‐level characteristics not evident at the composite level. More research is needed where community and nurse‐level factors may indirectly affect patient safety. Impact This study's findings on the role of community contexts can inform policymakers designing value‐based care programs and healthcare management administrators deliberating on magnet certification investments across diverse community settings. No patient or public contribution For this study of US hospitals' organizational performance, we did not engage members of the patient population nor the general public. However, the multi‐disciplinary research team does include diverse perspectives.