Citations 3
The paraneurium and the tumefactive appearance of peripheral nerve neurolymphomatosis: illustrative case
Kendziora, Ryan W., Wismayer, David J. Schembri, Spinner, Robert J. , Schembri Wismayer, David J, Barone, Damiano G. , Broski, Stephen M.
Journal of Neurosurgery: Case Lessons | April 22, 2024 | Volume: 7 | Issue: 17 | Pages: No page available
BACKGROUND Peripheral neurolymphomatosis (NL) is an often-misdiagnosed condition characterized by lymphomatous infiltration within the peripheral nerves. Its rarity and complexity frequently result in delayed diagnosis and suboptimal patient outcomes. This study aims to elucidate the role of the paraneurium (circumneurium) in NL, emphasizing its diagnostic and therapeutic significance. OBSERVATIONS A 72-year-old man presented with lesions on his right lower eyelid. Initial diagnostics were inconclusive until an excisional biopsy confirmed extranodal marginal zone lymphoma. Following a complete metabolic response to rituximab treatment, the patient relapsed 14 months later with progressive lymphoma and bilateral sciatic nerve involvement, as confirmed by positron emission tomography–computed tomography and magnetic resonance imaging. LESSONS This paper underscores the critical role of the paraneurium in NL, enhancing understanding of its pathophysiology. Integrating advanced imaging techniques have proved essential in accurately identifying neurolymphomatous involvement within the paraneurium. This study paves the way for more effective management strategies in NL and similar conditions, focusing on improving patient care and outcomes.
SMARCB1 and RB1 Gene: Novel Mutations in Neuroendocrine Tumors of Sinonasal Cavity
Chatzopoulos, Kyriakos , Wismayer, David J. Schembri, McKnight, Tory , Klug, Theodore , Barton, Blair M. , Bar‐Ad, Voichita , Johnson, Jennifer, Toskala, Elina , Rabinowitz, Mindy, Nyquist, Gurston , Chitguppi, Chandala , Gargano, Stacey , Choby, Garret , Low, Christopher M. , D’Souza, Glen , Parsel, Sean M. , Rosen, Marc R
Journal of Neurological Surgery Part B: Skull Base | March 4, 2022 | Volume: 83 | Issue: S 01 | Pages: S1-S270
Intramuscular Dirofilariasis Mimicking an Orbital Metastasis in a Patient with Breast Cancer
Henderson, Brett , Eckel, Laurence J. , Schwartz, Kara M., Pritt, Bobbi S. , Wismayer, David J. Schembri, Garrity, James A., Hunt, Christopher H. , Diehn, Felix E. , Pritt, Bobbi S
Case Reports in Radiology | September 14, 2012 | Volume: 2012 | Issue: No issue available | Pages: 1-3
We present the unusual case of a 74 year-old female with a history of breast cancer who presented with acute painless orbital swelling and vertical diplopia. MRI revealed a focal enhancing mass within the superior rectus muscle. As the concern for metastatic disease was high, surgical biopsy was performed and revealed an unusual mimicker of metastatic disease, the parasitic infection dirofilariasis.