Citations 3
A long-term human adipocyte organoid model reveals aging-associated responses to intermittent hypoxia
Dong, Yunzhou , Wang, Jingjing , Feng, Feifei, Ali, Isra H. , Chen, Lida, Karim, Shahid , Bock, Joshua M. , Somers, Virend K., Somers, Virend K. , Somers, Virend K. , Bock, Joshua
American Journal of Physiology-Cell Physiology | March 18, 2026 | Volume: 330 | Issue: 4 | Pages: C1093-C1106
Establishes a robust long-term human adipocyte organoid culture system maintained for over 90 days. Recapitulates key features of OSA-related intermittent hypoxia in human adipocytes in vitro. Demonstrates IH-induced adipocyte aging, including ultrastructural damage and epigenetic reprogramming. Identifies impaired adipogenesis and insulin signaling under intermittent hypoxia. Provides a physiologically relevant platform for mechanistic studies and drug screening.
3D-printing technologies and biomaterial innovations for bone tissue engineering: current status and future perspectives
Husien, Shimaa , Mamdouh, Wael , Ali, Isra H. , Mamdouh, Wael
Journal of Biomaterials Science, Polymer Edition | February 10, 2026 | Volume: No volume available | Issue: No issue available | Pages: 1-36
Optimization, thermo-oxidative stability, and biological activities of vitamin E-chitosan–TPP nanoformulations
Ali, Hussein M. , Attia, Mohamed H. , Mamdouh, Wael , Rashed, Eman N., Ali, Isra H. , Mamdouh, Wael
RSC Advances | January 26, 2026 | Volume: 16 | Issue: 6 | Pages: 5410-5426
Enhancing stability is a crucial factor in selecting bioactive compounds in most applications, while encapsulation techniques have proven to be a promising solution.