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Farrell, Lily

https://orcid.org/0009-0008-5612-5503

Mayo Clinic

University College Dublin

Citations 1

Practice Patterns and Outcomes of Dacryocystorhinostomy for Secondary Nasolacrimal Duct Obstruction
Farrell, Lily , Kopinski, Piotr K., Hassoun, Mohamad Rani , Graves, Jeffrey P., Stokken, Janalee K. , Tooley, Andrea A. , Farrell, Lily C , Carlson, Matthew L , Bradley, Elizabeth A. , Wagner, Lilly H.

American Journal of Rhinology & Allergy | October 8, 2025 | Volume: 40 | Issue: 2 | Pages: 112-117

10.1177/19458924251386210 Get It

Background Sinonasal pathology, such as chronic inflammatory disease or neoplasm, can cause secondary nasolacrimal duct obstruction (sNLDO). There is a paucity of data on dacryocystorhinostomy (DCR) techniques and outcomes for NLDO secondary to known sinonasal pathologies. Objective To describe case characteristics, management, and surgical outcomes of sNLDO at a tertiary academic center. Methods Charts of DCR cases with at least 3 months follow-up done at a single institution over a 5-year period (2018-2022) were reviewed. Patient and surgical characteristics were recorded and compared between secondary and primary NLDO groups. The primary outcome was early functional success of DCR, assessed by improvement or resolution of epiphora at 3 months. Results A total of 236 cases were included. Of those, 79 (33.5%) were classified as secondary NLDO associated with sinonasal pathology. Reasons for sNLDO were sinonasal cancer (46.8%), chronic inflammatory disease (24.1%), trauma (16.5%), or prior head and neck radiation (31.6%). When comparing primary acquired NLDO to sNLDO cases, DCR for sNLDO was more likely to be performed endoscopically (68.4% vs 31.8%, P < .01), by a multidisciplinary team of rhinologist and oculoplastic surgeon (70.9% vs 8.3%, P < .01), and required bilateral surgery (36.7% vs 5.7%, P < .01). The overall functional success rate was 79.7% for sNLDO compared to 87.9% for primary acquired NLDO ( P < .01). Revision surgery for sNLDO, history of sinonasal malignancy, and radiation were associated with lower functional success rates (66.7%, 70.3%, and 68.0%, respectively). Canalicular pathology was more common in sNLDO cases (29.0% vs 8.3%, P < .01). Conclusions Secondary NLDO was more commonly managed with an endoscopic approach by a multidisciplinary team. Revisions for sNLDO, as well as cases with a history of sinonasal malignancy and radiation, had a markedly lower success rate, and sNLDO was frequently associated with canalicular obstruction. These findings may facilitate surgical planning and patient counseling.