Citations 1
Assessing Mucosal Recovery During the First 15 Months of Adopting a Gluten-Free Diet in Children With Celiac Disease
Chang, Denis , Wong, Madison , Davidowitz, Cleo R., Absah, Imad , Badalyan, Vahe , Chaaban, Mohammad Karam, Fahey, Lisa M. , Isaac, Daniela Migliarese , Khanna, Maya, Lansing, Marihan, Liu, Edwin , Raber, Catherine , Singh, Arunjot , Stahl, Marisa G. , Walsh, Catharine M. , Silvester, Jocelyn A. , Leonard, Maureen M. , Chaaban, Mohammad K, Silvester, Jocelyn A , Walsh, Catharine M , Khanna, Maya
American Journal of Gastroenterology | March 14, 2025 | Volume: 120 | Issue: 7 | Pages: 1657-1661
INTRODUCTION: Determine contemporary rates of early mucosal recovery in children with celiac disease (CeD). METHODS: Multicenter retrospective cohort study in Canada and the United States. Children diagnosed with CeD between 2016 and 2021 who underwent a follow-up biopsy within 15 months of diagnosis were included. RESULTS: Overall, 96 of 130 children (74%) had mucosal recovery, including 48% children (12/25) who were assessed within 3 months. Musculoskeletal symptoms at diagnosis were the only clinical characteristic associated with persistent enteropathy. DISCUSSION: While mucosal recovery can occur within months, more than a quarter of children with CeD had persistent enteropathy within 15 months of treatment.