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Transtrum, M. Bryant

https://orcid.org/0009-0002-1979-9185

Mayo Clinic

Mayo Clinic

Citations 3

Three-dimensional biomechanical analysis of flexible intramedullary nailing constructs in length-unstable pediatric femur fractures
Grigoriou, Emmanouil , Transtrum, M. Bryant , Deshpande, Ameya H., Doak, Jeremy P., Ehrensberger, Mark T. , Varas-rodriguez, Emil, Varas‐Rodríguez, Emil , Deshpande, Ameya H.

Journal of Pediatric Orthopaedics B | June 18, 2025 | Volume: 34 | Issue: 6 | Pages: 579-587

10.1097/bpb.0000000000001267 Get It

Flexible intramedullary nail fixation of pediatric femoral shaft fractures offers advantages such as shorter hospital stays, faster return to function, and less associated costs when compared with traction and casting. This study compared the biomechanical performance of three configurations: 2CS, 2CL, and 3CL. Thirty synthetic femur models with identical, length-unstable, spiral fractures were tested using a three-dimensional camera system to assess real-time micromotion. Three groups were analyzed: (a) 2CS – two 3.5 mm C- and S-shaped nails inserted anterograde, (b) 2CL – one ‘C’ and one ‘S’ shaped 3.5 mm titanium nail-inserted retrograde from a single lateral entry, (c) 3CL – two ‘C’ shaped 3.5 mm titanium nails inserted medially and laterally with a third ‘C’ shaped 2.5 mm nail placed retrograde from an anterolateral site. Torsional loading, cyclical loading, and load-to-failure tests were conducted. The 3CL configuration demonstrated superior biomechanical performance. It exhibited the highest torsional stiffness [0.67 ± 0.06 Nm/° for external rotation (ER), 0.404 = ± 0.06 Nm/° for internal rotation (IR); P = 0.002], least displacement (0.05 ± 0.02 vs. 0.30 ± 0.02 mm for 2CL and 0.57 ± 0.05 mm for 2CS; P = 0.012), and required the highest load-to-failure (162 ± 83 vs. 1064 ± 75 N for 2CL and 790 ± 34 N for 2CS; P = 0.016).The 3CL configuration provided superior strength and stability across all tests, supporting its role in the fixation of length-unstable pediatric femoral fractures.
Tibiopelvic Rotational Arthroplasty for Pediatric Gorham-Stout Disease
Grigoriou, Emmanouil , Transtrum, M. Bryant , Oishi, Scott N. , Johnston, Charles E. , Johnson, Megan , Oishi, Scott , Johnson, Megan E

JBJS Case Connector | December 5, 2024 | Volume: 14 | Issue: 4 | Pages: No page available

10.2106/jbjs.cc.24.00172 Get It

Case: This is a case of a 6-year-old patient diagnosed with Gorham-Stout disease (GSD), a rare lymphangiogenic skeletal disorder, localized to the left femur. Initial nonoperative treatment with pharmaceuticals and bracing was unsuccessful. We describe a definitive operative treatment with radical femoral resection and a modified rotationplasty technique through a tibiopelvic rotational hip arthroplasty. At 2-year follow-up, the patient was able to walk with a prosthetic device. Conclusion: The use of this modified rotationplasty technique is an effective treatment option for patients with femoral GSD to improve function and quality of life.
How Long Can You Delay? Curve Progression While Awaiting Vertebral Body Tethering Surgery
Regan, Christina , Transtrum, M. Bryant , Jilakara, Bharadwaj, Milbrandt, Todd A. , Larson, A. Noelle , Larson, A Noelle

Journal of Clinical Medicine | April 11, 2024 | Volume: 13 | Issue: 8 | Pages: 2209

10.3390/jcm13082209 Get It

Background: The implications of delaying surgical intervention for patients with adolescent idiopathic scoliosis (AIS) wishing to undergo vertebral body tethering (VBT) have not yet been explored. It is important to understand how these delays can impact surgical planning and patient outcomes. Methods: This was a retrospective review that analyzed all AIS patients treated between 2015 and 2021 at a single tertiary center. Time to surgery from initial surgical consultation and ultimate surgical plan were assessed. Patient characteristics, potential risk factors associated with increased curve progression, and reasons for delay were also analyzed. Results: 174 patients were evaluated and 95 were scheduled for VBT. Four patients later required a change to posterior spinal fusion (PSF) due to excessive curve progression. Patients requiring PSF were shown to have significantly longer delays than those who received VBT. Additionally, longer delays, younger age, greater curve progression, and lower skeletal maturity were correlated with significant curve progression (≥5 degrees). Conclusions: Surgical delays for AIS patients awaiting VBT may lead to significant curve progression and necessitate more invasive procedures. Patients with longer delays experienced an increased risk of needing PSF instead of VBT. Of those requiring PSF, the majority were due to insurance denials. Optimizing surgical timing and shared decision-making among patients, families, and healthcare providers are essential for achieving the best outcomes.