Citations 1
CALR mutation burden in essential thrombocythemia and disease outcome
Guglielmelli, Paola , Szuber, Natasha , Gangat, Naseema , Capecchi, Giulio , Maccari, Chiara , Harnois, Michaël, Karrar, Omer , Abdelmagid, Maymona, Balliu, Manjola , Nacca, Elena, Atanasio, Alessandro , Sestini, Ilaria, Désilets, Audrey , Loscocco, Giuseppe Gaetano , Rotunno, Giada, Busque, Lambert , Tefferi, Ayalew , Vannucchi, Alessandro M , Loscocco, Giuseppe Gaetano , Szuber, Natasha , Guglielmelli, Paola , Vannucchi, Alessandro M.
Blood | January 22, 2024 | Volume: 143 | Issue: 13 | Pages: 1310-1314
Abstract Among 281 patients with essential thrombocythemia and calreticulin (CALR) mutation, we found a variant allele frequency of ≥60% to be associated with significantly shortened myelofibrosis-free survival, mostly apparent with CALR type-1 and CALR type-indeterminate mutations.