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Camp, Christopher L.

https://orcid.org/0000-0003-3058-7327

Mayo Clinic

Mayo Clinic

Citations 54

Artificial Intelligence Can Define and Predict the “Optimal Observed Outcome” After Anterior Shoulder Instability Surgery: An Analysis of 200 Patients With 11‐Year Mean Follow‐Up
Till, Sara E., Lu, Yining , Reinholz, Anna K., Boos, Alexander M. , Krych, Aaron J. , Okoroha, Kelechi R. , Camp, Christopher L. , Lu, Yining , Camp, Christopher L. , Krych, Aaron J , Boos, Alexander

Arthroscopy, Sports Medicine, and Rehabilitation | July 22, 2023 | Volume: 5 | Issue: 4 | Pages: No page available

10.1016/j.asmr.2023.100773 Get It

Purpose To use unsupervised machine learning clustering to define the “optimal observed outcome” after surgery for anterior shoulder instability (ASI) and to identify predictors for achieving it. Methods Medical records, images, and operative reports were reviewed for patients <40 years old undergoing surgery for ASI. Four unsupervised machine learning clustering algorithms partitioned subjects into “optimal observed outcome” or “suboptimal outcome” based on combinations of actually observed outcomes. Demographic, clinical, and treatment variables were compared between groups using descriptive statistics and Kaplan‐Meier survival curves. Variables were assessed for prognostic value through multivariate stepwise logistic regression. Results Two hundred patients with a mean follow‐up of 11 years were included. Of these, 146 (64%) obtained the “optimal observed outcome,” characterized by decreased: postoperative pain (23% vs 52%; P < 0.001), recurrent instability (12% vs 41%; P < 0.001), revision surgery (10% vs 24%; P = 0.015), osteoarthritis (OA) (5% vs 19%; P = 0.005), and restricted motion (161° vs 168°; P = 0.001). Forty‐one percent of patients had a “perfect outcome,” defined as ideal performance across all outcomes. Time from initial instability to presentation (odds ratio [OR] = 0.96; 95% confidence interval [CI], 0.92‐0.98; P = 0.006) and habitual/voluntary instability (OR = 0.17; 95% CI, 0.04‐0.77; P = 0.020) were negative predictors of achieving the “optimal observed outcome.” A predilection toward subluxations rather than dislocations before surgery (OR = 1.30; 95% CI, 1.02‐1.65; P = 0.030) was a positive predictor. Type of surgery performed was not a significant predictor. Conclusions After surgery for ASI, 64% of patients achieved the “optimal observed outcome” defined as minimal postoperative pain, no recurrent instability or OA, low revision surgery rates, and increased range of motion, of whom only 41% achieved a “perfect outcome.” Positive predictors were shorter time to presentation and predilection toward preoperative subluxations over dislocations. Level of Evidence Level IV, retrospective cohort.
Nonoperative Management of Degenerative Medial Meniscus Posterior Root Tears: Poor Outcomes at a Minimum 10-Year Follow-up
Krych, Aaron J. , Lamba, Abhinav , Wang, Allen S. , Boos, Alexander M. , Camp, Christopher L. , Levy, Bruce A. , Stuart, Michael J. , Camp, Christopher L. , Krych, Aaron J , Stuart, Michael J , Wang, Allen , Lamba, Abhinav , Boos, Alexander , Hevesi, Mario

The American Journal of Sports Medicine | July 12, 2023 | Volume: 51 | Issue: 10 | Pages: 2603-2607

10.1177/03635465231185132 Get It

Background: Medial meniscus posterior root tears (MMPRTs) cause pain and dysfunction and are associated with poor clinical outcomes with nonoperative management at short-term follow-up. However, little is known about the long-term natural history of these tears. Purpose: The purpose of this study was to (1) provide an update to a previous minimum 2-year study on the natural progression of these tears and (2) evaluate long-term patient-reported and radiographic outcomes. Study Design: Case series (prognosis); Level of evidence, 4. Methods: A retrospective review was performed on a cohort of patients with untreated MMPRTs, diagnosed between 2005 and 2013, who were followed clinically using International Knee Documentation Committee (IKDC), visual analog scale for pain, and Tegner activity scores as well as radiographically at a minimum 10-year follow-up. Failure was defined as conversion to arthroplasty or a severely abnormal subjective IKDC score <75.4. Results: Overall, 5 (10%) of the original 52 patients with minimum 2-year outcomes were subsequently lost to follow-up. The remaining 47 patients (21 male, 26 female) were followed for a mean of 14 ± 2 years (range, 11-18 years). At final follow-up, 25 patients (53%) had progressed to total knee arthroplasty, 8 (17%) were deceased, and 14 (30%) had not progressed to total knee arthroplasty. The mean IKDC and Tegner activity scores for the 14 patients with remaining MMPRTs were 51.6 ± 22.2 and 3.1 ± 1.1, respectively, and the mean visual analog scale score was 4.4 ± 3.0. Radiographically, the mean Kellgren-Lawrence grade progressed from 1.2 ± 0.7 at baseline to 2.6 ± 0.5 at final follow-up ( P < .001). At a minimum 10-year follow-up, 37 of 39 living patients (95%) had failed nonoperative treatment. Conclusion: Poor clinical and radiographic outcomes were associated with the nonoperative treatment of degenerative MMPRTs at long-term follow-up. This study provides a valuable update on the natural history and long-term prognosis of nonoperatively treated MMPRTs.
Surgical Stabilization for Recurrent Patellar Instability in Competitive Wrestlers: Outcomes, Reoperations, and Return to Play at 6-Year Mean Follow-up
Feroe, Aliya G. , Smith, John-Rudolph H. , Stuart, Michael J. , Camp, Christopher L. , Krych, Aaron J. , Smith, John R. , Marigi, Erick M. , Stuart, Michael J , Camp, Christopher L. , Krych, Aaron J , Smith, John-Rudolph , Hevesi, Mario

The American Journal of Sports Medicine | June 29, 2023 | Volume: 51 | Issue: 10 | Pages: 2608-2616

10.1177/03635465231182143 Get It

Background: The extent to which recurrent patellar instability (RPI) affects wrestlers has not been thoroughly examined. Purpose: To assess return to wrestling (RTW), patient-reported outcomes, and reoperation rates after patellofemoral stabilization surgery (PFSS) for RPI in a cohort of competitive wrestlers. Study Design: Cohort study; Level of evidence, 3. Methods: All competitive wrestlers with a history of RPI and subsequent PFSS performed at a single institution between 2000 and 2020 were identified. Primary PFSS procedures included medial patellofemoral (MPFL) reconstruction (n = 31; 50%); MPFL repair (n = 22; 35.5%); or other PFSS (n = 9; 14.5%), such as tibial tubercle osteotomy, lateral retinacular release, and/or medial retinacular reefing. Exclusion criteria included revision PFSS or concomitant anterior cruciate ligament reconstruction or multiligament knee injury. Surgical failure was defined as subsequent patellar dislocation despite operative management or need for secondary PFSS. Results: Ultimately, 62 knees in 56 wrestlers with a mean age of 17.0 years (range, 14.0-22.8 years) were included at a mean follow-up of 6.6 years (range, 2.0-18.8 years). RTW occurred in 55.3% of wrestlers at a mean ± SD 8.8 ± 6.7 months. Among PFSS types, no differences were observed in rates of RTW ( P = .676), postoperative pain ( P = .176), Tegner activity level ( P = .801), International Knee Documentation Committee ( P = .378), Lysholm ( P = .402), or Kujala scores ( P = .370). RPI was the most common postoperative complication (n = 13; 21.0%). MPFL reconstruction had the lowest rate of RPI (6.5% vs 27.3% [repair] vs 55.6% [other]; P = .005) and surgical failure (9.7% vs 31.8% [repair] vs 55.6% [other]; P = .008). Kaplan-Meier survivorship free from surgical failure of the entire cohort was 91.9% at 1 year, 77.7% at 5 years, and 65.7% at 15 years. MPFL reconstruction had the highest survivorship when compared with MPFL repair and other PFSS up to 10 years after the index surgery (90.3% vs 64.1% vs 27.8%; P = .048). Conclusion: RPI remains a concern for competitive wrestlers after PFSS. MPFL reconstruction may serve as a more durable surgical treatment option with lower rates of RPI and failure when compared with other PFSS procedures at up to 10 years after surgery.
Patients Aged >50 Years With Anterior Shoulder Instability Have a Decreased Risk of Recurrent Dislocation After Operative Treatment Compared With Non‐Operative Treatment
Smartt, Anne A. , Wilbur, Ryan R. , Song, Bryant M. , Krych, Aaron J. , Okoroha, Kelechi R. , Camp, Christopher L. , Okoroha, Kelechi, Camp, Christopher L. , Krych, Aaron J , Barlow, Jonathan D.

Arthroscopy, Sports Medicine, and Rehabilitation | May 6, 2023 | Volume: 5 | Issue: 3 | Pages: No page available

10.1016/j.asmr.2023.03.014 Get It

Purpose To compare the clinical outcomes of operative and nonoperative management, identify risk factors for recurrent instability, and identify risk factors for progression to surgery after failed nonoperative management for patients with first‐time anterior shoulder dislocation after the age of 50 years. Methods An established geographic medical record system was used to identify patients who experienced a first‐time anterior shoulder dislocation after the age of 50 years. Patient medical records were reviewed to identify treatment decisions and outcomes of interest, including rates of frozen shoulder and nerve palsy, progression to osteoarthritis, recurrent instability, and progression to surgery. Outcomes were evaluated using Chi‐square tests and survivorship curves were generated using Kaplan‐Meier methods. A Cox model was developed to evaluate for potential risk factors of recurrent instability and progression to surgery after an initial trail of at least 3 months of nonoperative treatment. Results 179 patients were included with a mean follow‐up of 11 years. 14% ( n = 26) underwent early surgery within 3 months and 86% ( n = 153) were initially treated nonoperatively. Mean age (59 years), was similar for both groups, but those that underwent early surgery had an increased rate of full‐thickness rotator cuff tears (82% vs 55%; P = .01), labral tears (24% vs 8.0%; P = .01), and humeral head fracture (23% vs 8.5%; P = .03). When comparing the early surgery group to the nonoperative group, there were similar rates of persistent moderate‐severe pain (19% vs 17%; P = .78) and frozen shoulder (8 vs 9%, respectively; P = .87) at final follow‐up. Although nerve palsy (19% vs 8%; P = .08) and progression to osteoarthritis (20% vs 14%; P = .40) were more common in surgical patients, they experienced lower rates of recurrent instability after surgical intervention (0% vs 15%; P = .03) compared to nonoperatively treated patients. Increasing number of instability events prior to presentation was the greatest risk factor for recurrent instability (HR 232; P < .01). Fourteen percent ( n = 21) failed initial nonoperative treatment and proceeded to surgical intervention at an average of 4.6 years after the initial instability event, and the greatest risk factors for progression to surgery were recurrent instability (HR 3.41; P < .01). Conclusions Although the majority of patients >50 years that experience ASI are treated nonoperatively, those that require surgery tend to have more significant injury pathology, a lower risk of recurrent instability after surgery, but a higher progression to osteoarthritis compared to patients that do not require surgical intervention. There was no difference in pain severity at final follow‐up, rates of frozen shoulder or nerve palsy between patients who underwent initial nonoperative treatment after instability and those who underwent surgery. A history of multiple instability episodes prior to presentation was the greatest predictor of recurrent instability and failure of nonoperative treatment and progression to surgery. Level of Evidence Level III, retrospective cohort study.
Improved Yet Varied Clinical Outcomes Observed With Comparison of Arthroscopic Superior Capsular Reconstruction Versus Arthroscopy‐Assisted Lower Trapezius Transfer for Patients With Irreparable Rotator Cuff Tears
Marigi, Erick M. , Jackowski, Jacob R., Barlow, Jonathan D. , Morrey, Mark E. , Camp, Christopher L. , Sánchez‐Sotelo, Joaquín , Elahi, Muhammad A , Barlow, Jonathan, Sanchez-Sotelo, Joaquin, Sanchez-Sotelo, J. , Camp, Christopher L. , Marigi, Erick , Barlow, Jonathan D , Morrey, Mark E , Elahi, Muhammad A.

Arthroscopy | May 2, 2023 | Volume: 39 | Issue: 10 | Pages: 2133-2141

10.1016/j.arthro.2023.04.012 Get It

Purpose To evaluate the outcomes of arthroscopic superior capsular reconstruction (SCR) and arthroscopy‐assisted lower trapezius tendon transfer (LTT) for posterosuperior irreparable rotator cuff tears (IRCTs). Methods Over an almost 6‐year period (October 2015 to March 2021), all patients who underwent IRCT surgery with a minimum 12‐month follow‐up period were identified. For patients with a substantial active external rotation (ER) deficit or lag sign, LTT was preferentially selected. Patient‐reported outcome scores included the visual analog scale (VAS) pain score, strength score, American Shoulder and Elbow Surgeons Standardized Shoulder Assessment Form (ASES) score, Single Assessment Numeric Evaluation (SANE) score, and Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH) score. Results We included 32 SCR patients and 72 LTT patients. Preoperatively, LTT patients had more advanced teres minor fatty infiltration (0.3 vs 1.1, P = .009), a higher global fatty infiltration index (1.5 vs 1.9, P = .035), and a higher presence of the ER lag sign (15.6% vs 48.6%, P < .001). At a mean follow‐up of 2.9 ± 1.3 years (range, 1.0‐6.3 years), no differences in patient‐reported outcome scores were observed. Postoperatively, SCR patients had a lower VAS score (0.3 vs 1.1, P = .017), higher forward elevation (FE) (156° vs 143°, P = .004), and higher FE strength (4.8 vs 4.5, P = .005) and showed greater improvements in the VAS score (6.8 vs 5.1, P = .009), FE (56° vs 31°, P = .004), and FE strength (1.0 vs 0.4, P < .001). LTT patients showed greater improvement in ER (17° vs 29°, P = .026). There was no statistically significant between‐cohort difference in complication rate (9.4% vs 12.5%, P = .645) or reoperation rate (3.1% vs 10%, P = .231). Conclusions With adequate selection criteria, both SCR and LTT provided improved clinical outcomes for posterosuperior IRCTs. Additionally, SCR led to better pain relief and restoration of FE whereas LTT provided more reliable improvement in ER. Level of Evidence Level III, treatment study with retrospective cohort comparison.
Cumulative group metrics: a new and efficient method to measure the scientific impact of research groups
Moll, Uta, Camp, Christopher L. , Bedi, Asheesh , Khoury, Anthony , Villinger, Sarah M., Higgins, Laurence D. , Wijdicks, Coen A. , Khoury, Anthony N , Camp, Christopher L. , Wijdicks, Coen A

Annals of Medicine & Surgery | March 2, 2023 | Volume: 85 | Issue: 2 | Pages: 124-129

10.1097/ms9.0000000000000086 Get It

Background: Various metrics have emerged for assessing scientific impact, most of which are based on complex calculations and, in many cases, are not freely available. Moreover, most of these metrics are not intended for assessing the scientific impact of research groups. Cumulative group metrics are proposed as an efficient and cost-effective strategy for measuring group scientific impact. Materials and methods: The authors collected peer-reviewed output in 2020 from two academic orthopedic surgery departments [University of Michigan (UM) and Mayo Clinic Rochester (MC)] and one medical device research department [Arthrex Inc. (AI)]. The sites evaluated the Cumulative Group Number of Publications (CGNP), Cumulative Journal Impact Factor (CJIF), Cumulative CiteScore (CCS), Cumulative SCImago Journal Rank (CSJR), and Cumulative Source Normalized Impact per Paper (CSNIP) for the three institutions. Results: In 2020, UM published 159 peer-reviewed studies, MC published 347 peer-reviewed studies, and AI supported 141 publications. The UM publications achieved a CJIF of 513, a CCS of 891, a CSJR of 255, and a CSNIP of 247. The MC publications achieved a CJIF of 956, a CCS of 1568, a CSJR of 485, and a CSNIP of 508. AI-supported publications achieved a CJIF of 314, a CCS of 598, a CSJR of 189, and a CSNIP of 189. Conclusion: The presented cumulative group metrics are an effective tool to assess the scientific impact of a research group. The cumulative submetrics can further evaluate research groups compared with other departments due to field normalization. Department leadership and funding agencies can utilize these metrics to evaluate research output quantitatively and qualitatively.
Platelet‐Rich Plasma and Marrow Venting May Serve as Cost‐Effective Augmentation Techniques for Isolated Meniscal Repair: A Decision‐Analytical Markov Model–Based Analysis
Oeding, Jacob F. , Berlinberg, Elyse J. , Marigi, Erick M. , Okoroha, Kelechi R. , Camp, Christopher L. , Barlow, Jonathan D. , Krych, Aaron J. , Camp, Christopher L. , Krych, Aaron J , Marigi, Erick , Barlow, Jonathan D , Oeding, Jacob F , Lu, Yining

Arthroscopy | March 1, 2023 | Volume: 39 | Issue: 9 | Pages: 2058-2068

10.1016/j.arthro.2023.02.018 Get It

Purpose To evaluate the cost‐effectiveness of 3 isolated meniscal repair (IMR) treatment strategies: platelet‐rich plasma (PRP)–augmented IMR, IMR with a marrow venting procedure (MVP), and IMR without biological augmentation. Methods A Markov model was developed to evaluate the baseline case: a young adult patient meeting the indications for IMR. Health utility values, failure rates, and transition probabilities were derived from the published literature. Costs were determined based on the typical patient undergoing IMR at an outpatient surgery center. Outcome measures included costs, quality‐adjusted life‐years (QALYs), and the incremental cost‐effectiveness ratio (ICER). Results Total costs of IMR with an MVP were $8,250; PRP‐augmented IMR, $12,031; and IMR without PRP or an MVP, $13,326. PRP‐augmented IMR resulted in an additional 2.16 QALYs, whereas IMR with an MVP produced slightly fewer QALYs, at 2.13. Non‐augmented repair produced a modeled gain of 2.02 QALYs. The ICER comparing PRP‐augmented IMR versus MVP‐augmented IMR was $161,742/QALY, which fell well above the $50,000 willingness‐to‐pay threshold. Conclusions IMR with biological augmentation (MVP or PRP) resulted in a higher number of QALYs and lower costs than non‐augmented IMR, suggesting that biological augmentation is cost‐effective. Total costs of IMR with an MVP were significantly lower than those of PRP‐augmented IMR, whereas the number of additional QALYs produced by PRP‐augmented IMR was only slightly higher than that produced by IMR with an MVP. As a result, neither treatment dominated over the other. However, because the ICER of PRP‐augmented IMR fell well above the $50,000 willingness‐to‐pay threshold, IMR with an MVP was determined to be the overall cost‐effective treatment strategy in the setting of young adult patients with isolated meniscal tears. Level of Evidence Level III, economic and decision analysis.
Osteochondritis Dissecans of the Capitellum of the Elbow: Improved Outcomes in Surgically Treated Versus Nonoperatively Treated Patients at Long‐Term Follow‐up
Braig, Zachary V. , Uvodich, Mason E. , Till, Sara E., Reinholz, Anna K., Morrey, Mark E. , Sánchez‐Sotelo, Joaquín , O’Driscoll, Shawn W. , Camp, Christopher L. , Sanchez-Sotelo, J. , Camp, Christopher L. , Fitzsimmons, James S , Morrey, Mark E

Arthroscopy, Sports Medicine, and Rehabilitation | February 24, 2023 | Volume: 5 | Issue: 2 | Pages: No page available

10.1016/j.asmr.2023.01.011 Get It

Purpose To (1) report the long‐term outcomes associated with both operative and nonoperative management of capitellar osteochondritis dissecans (OCD), (2) identify factors associated with failure of nonoperative management, and (3) determine whether delay in surgery affects final outcomes. Methods All patients who received a diagnosis of capitellar OCD from 1995‐2020 within a geographic cohort were included. Medical records, imaging studies, and operative reports were manually reviewed to record demographic data, treatment strategies, and outcomes. The cohort was divided into 3 groups: (1) nonoperative management, (2) early surgery, and (3) delayed surgery. Delayed surgery (surgery ≥6 months after symptom onset) was considered failure of nonoperative management. Results Fifty elbows with a mean follow‐up period of 10.5 years (median, 10.3 years; range, 1‐25 years) were studied. Of these, 7 (14%) were definitively treated nonoperatively, 16 (32%) underwent delayed surgery after at least 6 months of failed nonoperative treatment, and 27 (54%) underwent early surgical intervention. When compared with nonoperative management, surgical management resulted in superior Mayo Elbow Performance Index pain scores (40.1 vs 33, P = .04), fewer mechanical symptoms (9% vs 50%, P < .01), and better elbow flexion (141° vs 131°, P = .01) at long‐term follow‐up. Older patients trended toward increased failure of nonoperative management ( P = .06). The presence of an intra‐articular loose body predicted failure of nonoperative management ( P = .01; odds ratio, 13). Plain radiography and magnetic resonance imaging had poor sensitivities for identifying loose bodies (27% and 40%, respectively). Differences in outcomes after early versus delayed surgical management were not observed. Conclusions Nonoperative management of capitellar OCD failed 70% of the time. Elbows that did not undergo surgery had slightly more symptoms and decreased functional outcomes compared with those treated surgically. The greatest predictors of failure of nonoperative treatment were older age and presence of a loose body; however, an initial trial of nonoperative treatment did not adversely impact the success of future surgery. Level of Evidence Level III, retrospective cohort study.
Lateral Epicondylitis
Marigi, Erick M. , Dancy, Malik, Alexander, Andrew , Marigi, Ian , Clark, Julian , Camp, Christopher L. , Okoroha, Kelechi R. , Marigi, Ian M , Camp, Christopher L. , Okoroha, Kelechi R , Marigi, Erick , Alexander, Andrew S , Clark, Clarence Julian , Krych, Aaron J.

JBJS Reviews | February 17, 2023 | Volume: 11 | Issue: 2 | Pages: No page available

10.2106/jbjs.rvw.22.00170 Get It

» Lateral epicondylitis (LE) or tennis elbow is a common cause of elbow pain in the general population, especially women in the fourth and fifth decades of life who participate in repetitive forceful movements involving the wrist and forearm. » The pathogenesis of this overuse injury is believed to start from an overload event leading to a microtear in or near the origin of the extensor carpi radialis brevis that is subsequently prone to additional injury and structural weakness over time. » Treatment of LE often begins with a wide variety of nonoperative modalities including rest, nonsteroidal anti-inflammatory drugs, bracing, and physical therapy. For recalcitrant symptoms, additional nonoperative therapies are implemented; however, there remains a lack of comparative efficacy between these adjunct treatments. » In this article, we examine the available literature regarding nonoperative management of LE and provide supplementary insight into the effectiveness of current modalities.
A Number of Modifiable and Nonmodifiable Factors Increase the Risk for Elbow Medial Ulnar Collateral Ligament Injury in Baseball Players: A Systematic Review
Labott, Joshua R. , Leland, Devin P. , Till, Sara E., Diamond, Adam , Hintz, Christian, Camp, Christopher L. , Camp, Christopher L. , Hintz, Christian, Dines, Joshua S.

Arthroscopy | January 14, 2023 | Volume: 39 | Issue: 8 | Pages: 1938

10.1016/j.arthro.2022.12.036 Get It

Purpose To analyze the current literature regarding risk factors associated with medial ulnar collateral ligament (MUCL) injury in baseball players and to serve as a robust source for identifying modifiable risk factors that once optimized, have the potential to reduce injury risk. Methods Comprehensive search of the available literature was performed according to the Preferred Reporting Items for Systematic Reviews and Meta‐Analysis guidelines. Studies were included if they evaluated risk factors for MUCL injuries in the elbow of baseball players. Risk of bias assessment was performed via Methodological Index for Non‐randomized Studies (MINORS) scoring system. The Oxford Centre for Evidence‐Based Medicine was used to determine level of evidence. Variables of interest; player age, position, shoulder motion, humeral retrotorsion, joint laxity, strength, balance, geography, velocity, pitch count, pitch types, throwing volumes, and throwing mechanics were recorded. Results Twenty‐one studies were included in this systematic review. MINORS scores ranged from 75 to 87%, and variables demonstrated significant heterogeneity. Performance‐based risk factors for MUCL injury included: increased pitch count (both annual and per game), higher percentage of fastballs thrown, smaller pitch repertoire, and/or a loss of pitching velocity. Biomechanical studies demonstrated the relationship between decreased shoulder range of motion (total ROM, ER, IR, and abduction), increased humeral retrotorsion, increased elbow valgus opening in the throwing arm, lower Y‐Balance score, and increased lateral release position to increased MUCL injury. Conclusions Risk factors for MUCL injury can generally be categorized into 4 primary groups: 1) various player demographics and characteristics, 2) throwing too hard (high velocity), 3) throwing too much (pitch count/volume), and 4) throwing with poor mechanics. In this systematic review, the most significant nonmodifiable risk factors for MUCL injuries included: increased glenohumeral retrotorsion and elbow valgus opening. The most consistent modifiable risk factors included: total shoulder range of motion, pitch count, pitch selection, Y balance score, and lateral release position. Pitch velocity was inconsistent in literature, but most studies found this as a risk for injury. These risk factors may serve as appropriate targets for future evidence‐based injury mitigation strategies. Level of Evidence Level IV, systematic review of Level II‐IV studies.