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Mir, Mikael

Mayo Clinic

University of Minnesota

Citations 2

Cardiovascular Complications of Obstructive Sleep Apnea in the Intensive Care Unit and Beyond
Jain, Nitesh , Surani, Salim , Mushtaq, Hisham, Mir, Mikael, Jama, Abbas B, Rauf, Ibtisam , Jain, Shikha , Korsapati, Aishwarya Reddy, Chandramouli, Mantravadi Srinivasa, Boike, Sydney , Attallah, Noura , Hassan, Esraa, Chand, Mool, Bawaadam, Hasnain , Khan, Syed Anjum , Jain, Nitesh Kumar , Surani, Salim , Jama, Abbas Bashir, Boike, Sydney , Khan, Syed Anjum , Wahab, Abdul , Chowdhury, Arnab Roy , Khedr, Anwar

Medicina | October 9, 2022 | Volume: 58 | Issue: 10 | Pages: 1390

10.3390/medicina58101390 Get It

Obstructive sleep apnea (OSA) is a common disease with a high degree of association with and possible etiological factor for several cardiovascular diseases. Patients who are admitted to the Intensive Care Unit (ICU) are incredibly sick, have multiple co-morbidities, and are at substantial risk for mortality. A study of cardiovascular manifestations and disease processes in patients with OSA admitted to the ICU is very intriguing, and its impact is likely significant. Although much is known about these cardiovascular complications associated with OSA, there is still a paucity of high-quality evidence trying to establish causality between the two. Studies exploring the potential impact of therapeutic interventions, such as positive airway pressure therapy (PAP), on cardiovascular complications in ICU patients are also needed and should be encouraged. This study reviewed the literature currently available on this topic and potential future research directions of this clinically significant relationship between OSA and cardiovascular disease processes in the ICU and beyond.
A Case of Adult Multisystem Inflammatory Syndrome Following COVID-19 Vaccine
Brown, Meghan, Garbajs, Nika Zorko , Mushtaq, Hisham, Jama, Abbas B, Rauf, Ibtisam , Mir, Mikael, Korsapati, Aishwarya Reddy, Jain, Shikha , Adhikari, Ramesh , Lal, Amos , Domecq, Juan Pablo , Goksoy, Sarah, Bartlett, Brian, Jain, Nitesh , Khan, Syed Anjum , Garbajs, Nika Z, Zec, Simon , Khedr, Anwar , Koritala, Thoyaja , Jain, Nitesh Kumar, Lal, Amos , Domecq Graces, Juan Pablo , Mir, Mikael, Gajic, Ognjen , Sharma, Amit

Journal of Community Hospital Internal Medicine Perspectives | July 9, 2022 | Volume: 12 | Issue: 4 | Pages: 7-13

10.55729/2000-9666.1087 Get It

Multisystem inflammatory syndrome is a life-threatening condition associated with elevated inflammatory markers and multiple organ injury. A diagnosis of exclusion, it has been reported after severe acute respiratory syndrome coronavirus 2 infection (SARS-CoV-2) in children and adults; recently it has been described in some post-COVID-19 vaccinated individuals. The prognosis with supportive care and immunomodulatory therapy is good, although some individuals may require treatment in the intensive care unit (ICU). Here we report a case of a 58-year-old man who developed multi-organ failure after receiving the second dose of the Moderna mRNA-1273 COVID-19 vaccine. He required critical organ support in the ICU. An extensive workup was done to rule out alternative infectious and inflammatory processes. Following a period of gradual in-hospital convalescence, our patient made a full recovery. To our knowledge, this is the first comprehensively described case of multisystem inflammatory syndrome associated with Moderna mRNA-1273 COVID-19 vaccine in an adult over 50 years of age.