Citations 1
Development and Calibration of a Nanometer Manipulation and Measurement System for Molecular Biomechanical Testing
Luo, Zong-Ping, An, Kai , Luo, Zong-Ping
Advances in Bioengineering | January 31, 2022 | Volume: No volume available | Issue: No issue available | Pages: 221-222
Abstract An optical tweezers system has been adopted for molecular biomechanical testing. To achieve nanometer manipulation and measurement, the system was modified with a piezo-stage and an interferometer. A systematic calibration was then performed on the displacement resolution. The results revealed that the system has a nanometer resolution which is sufficient for the measurement of deformation and stiffness of single macro-molecules.