Citations 1
TSC1 loss increases risk for tauopathy by inducing tau acetylation and preventing tau clearance via chaperone-mediated autophagy
Alquezar, Carolina , Schoch, Kathleen M. , Geier, Ethan G., Ramos, Eliana Marisa , Scrivo, Aurora , Li, Kathy H., Argouarch, Andrea R. , Mlynarski, Elisabeth E. , Dombroski, Beth A. , DeTure, Michael , Yokoyama, Jennifer S. , Burlingame, Alma L. , Schellenberg, Gerard D. , Miller, Timothy M. , Miller, Bruce L. , Dombroski, Beth , Dickson, Dennis W , Cuervo, Ana M , Burlingame, Alma L , Schellenberg, Gerard D , Miller, Timothy M , Miller, Bruce L , Kao, Aimee W. , DeTure, Michael , Yokoyama, Jennifer , Alquezar, Carolina , Dickson, Dennis W.
Science Advances | November 5, 2021 | Volume: 7 | Issue: 45 | Pages: No page available
TSC1/hamartin haploinsufficiency increases risk for tauopathy by promoting tau acetylation and accumulation.