Citations 4
Multiple Sclerosis Disease Activity is Uncommon in Individuals With Pre-existing Multiple Sclerosis Exposed to Immune Checkpoint Inhibitor Therapy (P4-19.002)
Gill, Alexander, Krett, Jonathan, Quinn, Carson, Babcock, Lyndsey, Kaiser, Anna, Morrison, Andrew , Pisano, Thomas, Paracha, Atika, Dodson, Cory, Kopinsky, Hannah, Moninuola, Iwalewa , Alhassan, Said, Stewart, Wendy, Aguilera-Pena, Maria, Guerrero, Sofia Ramierz, Jean, Maxime, Lamb, Jessica, Piura, Yoav, CARRIER, Jordan, Arvas, Muhammed Ikbal, Camargo, Celeste, Bhise, Vikram, Linnoila, Jenny, Chaudhry, Vinay , Bhattacharyya, Shamik, Alvarez, E, Kantor, Daniel , Nelsion, Flavia, Rammohan, Kottil, Coyle, Patricia, Hemminger, Lauryn, Baldwin, Nicole, Hutton, George, Simpson, Alexandra, Barreras, Paula, Basuroski, Irena Dujmovic, Harrington, Cole, Douglas, Anne, Day, Gregory, Galetta, Kristin, Conway, Sarah, Gadani, Sachin, Wolf, Andrew, Probasco, John, Gill, Alexander J. , Krett, Jonathan D. , Rajarajan, Prashanth , Babcock, Lyndsey R., Pisano, Thomas John , Stewart, Wendy A. , Aguilera-Pena, María Paula , Modak, Nikhil, Jean, Maxime Junior , Piura, Yoav , Bhise, Vikram V. , Linnoila, Jenny, Bhattacharyya, Shamik , Coyle, Patricia, Hemminger, Lauryn, Hutton, George J., Barreras, Paula , Day, Gregory S. , Kister, Ilya , Galetta, Kristin , Roy, Shuvro , Probasco, John C.
Neurology | June 10, 2026 | Volume: 106 | Issue: 11_Supplement_1 | Pages: No page available
High Rates of Myasthenia Gravis Exacerbations in Individuals With Pre-existing Myasthenia Gravis Exposed to Immune Checkpoint Inhibitors (P11-9.021)
Gill, Alexander, Krett, Jonathan, Li, Carrie, Babcock, Lyndsey, Piura, Yoav, Morrison, Andrew , Pisano, Thomas, Dodson, Cory, Paracha, Atika, Kaiser, Anna, Alhassan, Said, Modak, Nikhil, Moninuola, Iwalewa , Jean, Maxime, CARRIER, Jordan, Arvas, Muhammed Ikbal, Stewart, Wendy, Lamb, Jessica, Aguilera-Pena, Maria, Camargo, Celeste, Bhise, Vikram, Chaudhry, Vinay , Linnoila, Jenny, Rammohan, Kottil, Nelsion, Flavia, O’Hare, Meabh, Roda, Ricardo, Baldwin, Nicole, Coyle, Patricia, Hemminger, Lauryn, Simpson, Alexandra, Barreras, Paula, Basuroski, Irena Dujmovic, Douglas, Anne, Harrington, Cole, Hutton, George, Galetta, Kristin, Day, Gregory, Conway, Sarah, Gadani, Sachin, Wolf, Andrew, Probasco, John, Krett, Jonathan D. , Babcock, Lyndsey R., Piura, Yoav , Pisano, Thomas John , Modak, Nikhil, Jean, Maxime Junior , CARRIER, Jordan, Stewart, Wendy A. , Aguilera-Pena, María Paula , Bhise, Vikram V. , Linnoila, Jenny, Bhattacharyya, Shamik , Roda, Ricardo H. , Coyle, Patricia, Hemminger, Lauryn, Barreras, Paula , Hutton, George J., Galetta, Kristin , Day, Gregory S. , Roy, Shuvro , Probasco, John C.
Neurology | June 10, 2026 | Volume: 106 | Issue: 11_Supplement_1 | Pages: No page available
Colistin neurotoxicity mimicking Guillain-Barré syndrome in a patient with cystic fibrosis: case report and review
Camargo, Celeste, Narula, Tathagat , Jackson, Daniel A., Padro, Teresa , Freeman, W David, Freeman, William D.
Oxford Medical Case Reports | September 13, 2021 | Volume: 2021 | Issue: 9 | Pages: No page available
ABSTRACT Guillain-Barré syndrome (GBS) is an immune-mediated polyneuropathy, which is characterized by areflexia and ascending paresthesia which can progress to a respiratory failure. Certain conditions, such as vasculitis and heavy metal and drug toxicity, may have misleadingly similar clinical presentation to GBS. We describe a case of a patient with cystic fibrosis and intravenous colistin-induced neurotoxicity mimicking GBS. The patient had used inhaled colistin on five occasions with no adverse effects, however, developed symptoms on the second day of intravenous treatment. Overlapping findings between immune-mediated polyneuropathy and drug-induced neurotoxicity include limb paresthesia and decreased reflexes. Perioral tingling, however, is a common presentation of colistin-induced neurotoxicity, and therefore, is an important differentiating factor. Early diagnosis prevents further neurologic decline, extensive unnecessary workup and potentially harmful incorrect management.
Comprehensive Perioperative Approach to Complex Spine Deformity Management
Camargo, Celeste, Bechtle, Perry S., Abode-Iyamah, Kingsley , Shah, Jaimin S., Freeman, William D.
Clinical Spine Surgery | August 2, 2021 | Volume: 35 | Issue: 7 | Pages: 310-318
Objective: Study perioperative strategies for optimizing neuroprotection in complex spine deformity correction surgery. Methods: We report the case of a patient with severe lumbar dextroscoliosis, thoracolumbar junction hyperkyphosis with a 40-degree Cobb angle levoconvex scoliosis who underwent spinal deformity correction with loss of neuromonitoring during surgery. We performed a literature review on perioperative management of complex spine deformity. Results: A 50-year-old man presented with lumbar pain and right L4 radiculopathy. Surgical intervention for deformity correction and decompression was indicated with T4−L4 posterior instrumentation L2/L3 and L3/L4 transforaminal lumbar interbody fusion. Surgery was aborted due to the loss of neuromonitoring. Postsurgery, the patient had left sensory deficit and the neurocritical care team clinically suspected and deduced the anatomic location of the spinal cord compression. Magnetic resonance imaging confirmed a T10−T11 hyperintensity suggestive of cord ischemia due to osteophyte compressing the spinal cord. The patient underwent a second corrective surgery with no intraoperative events and has no long-term neurological sequela. Conclusions: This case illustrates that a comprehensive perioperative approach and individualized risk factor assessment is useful in complex spine deformity surgery. Further research is needed to determine how this individualized comprehensive approach can lead to intraoperative and postoperative countermeasures that improved spine surgery outcomes. Level of Evidence: Level V.